IMP scientists publish 60 to 90 scientific papers in international peer-review journals every year. This evidence for the productivity and high scientific standard of the IMP is listed here in full – a directory of all scientific publications by IMP scientists since the establishment of the institute, organised by years and research groups.
Lineage tracing of Shh+ floor plate cells and dynamics of dorsal-ventral gene expression in the regenerating axolotl spinal cord.
Dev Growth Differ. 66(8):414-425Evolutionary adaptation of an HP1-protein chromodomain integrates chromatin and DNA sequence signals.
Elife. 13Rational correction of pathogenic conformational defects in HTRA1.
Nat Commun. 15(1):5944Suppression of toxic transgene expression by optimized artificial miRNAs increases AAV vector yields in HEK-293 cells.
Mol Ther Methods Clin Dev. 32(3):101280A polarized FGF8 source specifies frontotemporal signatures in spatially oriented cell populations of cortical assembloids.
Nat Methods.Quantitative imaging of loop extruders rebuilding interphase genome architecture after mitosis.
bioRxiv.Convergence of orphan quality control pathways at a ubiquitin chain-elongating ligase
bioRxiv . 10.1101/2024.08.07.607117Increase in ER-mitochondria contacts and mitochondrial fusion are hallmarks of mitochondrial activation during embryogenesis
bioRxiv . 10.1101/2024.06.11.598492v1Gpcpd1-GPC metabolic pathway is dysfunctional in aging and its deficiency severely perturbs glucose metabolism.
Nat Aging. 4(1):80-94Cancer Evolution: A Multifaceted Affair.
Cancer Discov. 14(1):36-48Targeted design of synthetic enhancers for selected tissues in the Drosophila embryo.
Nature. 626(7997):207-211A conserved fertilization complex bridges sperm and egg in vertebrates.
Show Preprint Cell.Transcriptional function of E2A, Ebf1, Pax5, Ikaros and Aiolos analyzed by in vivo acute protein degradation in early B cell development.
Nat Immunol. 25(9):1663-1677Genomic surveillance of SARS-CoV-2 evolution by a centralised pipeline and weekly focused sequencing, Austria, January 2021 to March 2023.
Euro Surveill. 29(23)Tumor necrosis factor α promotes clonal dominance of KIT D816V+ cells in mastocytosis: role of survivin and impact on prognosis.
Blood. 143(11):1006-1017Label-Free Sample Preparation for Single-Cell Proteomics.
Methods Mol Biol. 2817:1-7A molecular switch orchestrates the nuclear export of human messenger RNA
BioRxiv.mTOR activity paces human blastocyst stage developmental progression.
Cell.Homo-BacPROTAC-induced degradation of ClpC1 as a strategy against drug-resistant mycobacteria.
Nat Commun. 15(1):2005Alkylamine-tethered molecules recruit FBXO22 for targeted protein degradation.
Nat Commun. 15(1):5409A chromatin code for limb segment identity in axolotl limb regeneration.
Dev Cell. 59(16):2239-2253.e9Mouse neural tube organoids self-organize floorplate through BMP-mediated cluster competition.
Dev Cell. 59(15):1940-1953.e10The molecular mechanisms underpinning maternal mRNA dormancy.
Biochem Soc Trans.eIF4E1b is a non-canonical eIF4E protecting maternal dormant mRNAs.
Show Preprint EMBO Rep. 25(1):404-427Mime-seq 2.0: a method to sequence microRNAs from specific mouse cell types.
EMBO J. 43(12):2506-2525ARID1B controls transcriptional programs of axon projection in an organoid model of the human corpus callosum.
Cell Stem Cell. 31(6):866-885.e14A lyophilized open-source RT-LAMP assay for molecular diagnostics in resource-limited settings
medRxiv. 10.1101/2024.11.19.24317525Micropillar arrays, wide window acquisition and AI-based data analysis improve comprehensiveness in multiple proteomic applications.
Nat Commun. 15(1):1019Proteome-scale tagging and functional screening in mammalian cells by ORFtag.
Nat Methods.Identification of Pathogenic Pathways for Recurrence of Focal Segmental Glomerulosclerosis after Kidney Transplantation.
Diagnostics (Basel). 14(15)Pulling the strings on solid-to-liquid phase transitions in cell collectives.
Curr Opin Cell Biol. 86:102310Sororin is an evolutionary conserved antagonist of WAPL.
Nat Commun. 15(1):4729tRNA expression and modification landscapes, and their dynamics during zebrafish embryo development.
Show Preprint Nucleic Acids Res.Structural basis of human U5 snRNP late biogenesis and recycling.
Nat Struct Mol Biol.Murine neonatal cardiac regeneration depends on Insulin-like growth factor 1 receptor signaling.
Sci Rep. 14(1):22661Multiple ubiquitin ligases protect human genome integrity by targeting cancer-associated APOBEC3 deaminases for degradation
bioRxiv . 10.1101/2024.04.23.590688A dual ribosomal system in the zebrafish soma and germline
bioRxiv. doi:10.1101/2024.08.29.610041TRIM52 is a primate-specific player in the DNA repair process under tight proteolytic control by a triad of giant E3 ligases
bioRxiv . 10.1101/2024.05.16.594269UNC-45 assisted myosin folding depends on a conserved FX3HY motif implicated in Freeman Sheldon Syndrome.
Nat Commun. 15(1):6272Mechanism for the initiation of spliceosome disassembly.
Nature. 632(8024):443-450Red2Flpe-SCON: a versatile, multicolor strategy for generating mosaic conditional knockout mice.
Nat Commun. 15(1):4963Egr1 regulates regenerative senescence and cardiac repair.
Nat Cardiovasc Res. 3(8):915-932Frozen in time: analyzing molecular dynamics with time-resolved cryo-EM.
Structure. 31(1):4-19SPOC domain proteins in health and disease.
Genes Dev. 37(5-6):140-170Transcription shapes 3D chromatin organization by interacting with loop extrusion.
Show Preprint Proc Natl Acad Sci U S A. 120(11):e2210480120Testing pseudotopological and nontopological models for SMC-driven DNA loop extrusion against roadblock-traversal experiments.
Sci Rep. 13(1):8100Cohesin-mediated DNA loop extrusion resolves sister chromatids in G2 phase.
EMBO J. :e113475Tumor-derived prostaglandin E2 programs cDC1 dysfunction to impair intratumoral orchestration of anti-cancer T cell responses.
Immunity. 56(6):1341-1358.e11SLAMseq resolves the kinetics of maternal and zygotic gene expression during early zebrafish embryogenesis.
Show Preprint Cell Rep. 42(2):112070MS Annika 2.0 Identifies Cross-Linked Peptides in MS2-MS3-Based Workflows at High Sensitivity and Specificity.
J Proteome Res.Time-resolved cryo-EM (TR-EM) analysis of substrate polyubiquitination by the RING E3 anaphase-promoting complex/cyclosome (APC/C).
Nat Struct Mol Biol. 30(11):1663-1674SBNO2 is a critical mediator of STAT3-driven hematological malignancies.
Blood.X-linked inhibitor of apoptosis protein represents a promising therapeutic target for relapsed/refractory ALL.
EMBO Mol Med. 15(1):e14557An unbiased AAV-STARR-seq screen revealing the enhancer activity map of genomic regions in the mouse brain in vivo.
Sci Rep. 13(1):6745Author Correction: PCYT2-regulated lipid biosynthesis is critical to muscle health and ageing.
Nat Metab.PCYT2-regulated lipid biosynthesis is critical to muscle health and ageing.
Nat Metab. 5(3):495-515A de novo transcription-dependent TAD boundary underpins critical multiway interactions during antibody class switch recombination.
Show Preprint Mol Cell. 83(5):681-697.e7An automated nanowell-array workflow for quantitative multiplexed single-cell proteomics sample preparation at high sensitivity.
Mol Cell Proteomics. :100665MYC determines lineage commitment in kras driven primary liver cancer development.
J Hepatol.CTCF is a DNA-tension-dependent barrier to cohesin-mediated loop extrusion.
Show Preprint Nature. 616(7958):822-827How do molecular motors fold the genome?
Science. 382(6671):646-648Developmental cell fate choice in neural tube progenitors employs two distinct cis-regulatory strategies.
Dev Cell. 58(1):3-17.e8Low-density lipoprotein receptor-related protein 1 (LRP1) as an auxiliary host factor for RNA viruses.
Life Sci Alliance. 6(7)A phylogenetic profiling approach identifies novel ciliogenesis genes in Drosophila and C. elegans.
EMBO J. :e113616MS Ana: Improving Sensitivity in Peptide Identification with Spectral Library Search.
J Proteome Res. 22(2):462-470ABCC1 and glutathione metabolism limit the efficacy of BCL-2 inhibitors in acute myeloid leukemia.
Nat Commun. 14(1):5709Structural basis for regulation of apoptosis and autophagy by the BIRC6/SMAC complex.
Science. 379(6637):1117-1123Transposon waves at the water-to-land transition.
Curr Opin Genet Dev. 81:102059TurboID-based proteomic profiling of meiotic chromosome axes in Arabidopsis thaliana.
Nat Plants.Divergent molecular signatures in fish Bouncer proteins define cross-fertilization boundaries.
Show Preprint Nat Commun. 14(1):3506Essential role of the Pax5 C-terminal domain in controlling B cell commitment and development.
J Exp Med. 220(12)Reply to: Assessment of 3D MINFLUX data for quantitative structural biology in cells.
Nat Methods. 20(1):52-54Generating human blastoids modeling blastocyst-stage embryos and implantation.
Nat Protoc.Enhancers of the PAIR4 regulatory module promote distal VH gene recombination at the Igh locus.
EMBO J. 42(15):e112741Igh and Igk loci use different folding principles for V gene recombination due to distinct chromosomal architectures of pro-B and pre-B cells.
Nat Commun. 14(1):2316Cryo-EM structure of the chain-elongating E3 ubiquitin ligase UBR5.
EMBO J. 42(16):e113348Precision RNAi using synthetic shRNAmir target sites.
Elife. 12Clp-targeting BacPROTACs impair mycobacterial proteostasis and survival.
Cell. 186(10):2176-2192.e22A hydraulic feedback loop between mesendoderm cell migration and interstitial fluid relocalization promotes embryonic axis formation in zebrafish.
Dev Cell.Topological morphogenesis of neuroepithelial organoids.
Nat Phys. 19(2):177-183Widespread regulatory specificities between transcriptional co-repressors and enhancers in Drosophila.
Science. 381(6654):198-204Cohesin and CTCF do not assemble TADs in Xenopus sperm and male pronuclei.
Genome Res. 33(12):2094-107Correction: Biallelic PAX5 mutations cause hypogammaglobulinemia, sensorimotor deficits, and autism spectrum disorder.
J Exp Med. 220(1)Chromosome Conformation Capture for Large Genomes.
Methods Mol Biol. 2562:291-318Systematic identification and characterization of repressive domains in Drosophila transcription factors.
EMBO J. 42(3):e112100The NCOR-HDAC3 co-repressive complex modulates the leukemogenic potential of the transcription factor ERG.
Nat Commun. 14(1):5871Evolutionary adaptation of the chromodomain of the HP1-protein Rhino allows the integration of chromatin and DNA sequence signals
Show Preprint BioRxiv.A molecular network of conserved factors keeps ribosomes dormant in the egg.
Show Preprint Nature.Human Papillomavirus 42 Drives Digital Papillary Adenocarcinoma and Elicits a Germ Cell-like Program Conserved in HPV-Positive Cancers.
Cancer Discov. 13(1):70-84Single-cell brain organoid screening identifies developmental defects in autism.
Nature. 621(7978):373-380StarMap: a user-friendly workflow for Rosetta-driven molecular structure refinement.
Nat Protoc. 18(1):239-264Morphogenesis and development of human telencephalic organoids in the absence and presence of exogenous extracellular matrix.
EMBO J. 42(22):e113213Ethyl Cinnamate-Based Tissue Clearing Strategies.
Methods Mol Biol. 2562:123-133Label-free single cell proteomics utilizing ultrafast LC and MS instrumentation: A valuable complementary technique to multiplexing.
Proteomics. :e2200162Improving single cell proteomics experiments: how can we best utilize latest-generation data acquisition and MS instrument architecture?
Expert Rev Proteomics. :1-3Robust and Easy-to-Use One-Pot Workflow for Label-Free Single-Cell Proteomics.
Anal Chem. 95(9):4435-4445Immunopeptidomics in the Era of Single-Cell Proteomics.
Biology (Basel). 12(12)Cooperation between bHLH transcription factors and histones for DNA access.
Nature. 619(7969):385-393Baculovirus Production and Infection in Axolotls.
Methods Mol Biol. 2562:369-387Cohesin mediates DNA loop extrusion and sister chromatid cohesion by distinct mechanisms.
Mol Cell.CBFA2T3-GLIS2-dependent pediatric acute megakaryoblastic leukemia is driven by GLIS2 and sensitive to navitoclax.
Cell Rep. 42(9):113084Navigation and Use of Custom Tracks within the Axolotl Genome Browser.
Methods Mol Biol. 2562:273-289mRNA recognition and packaging by the human transcription-export complex.
Nature.Shuffled ATG8 interacting motifs form an ancestral bridge between UFMylation and autophagy.
EMBO J. :e112053Enhancers display constrained sequence flexibility and context-specific modulation of motif function.
Genome Res.In vitro modeling of the human dopaminergic system using spatially arranged ventral midbrain-striatum-cortex assembloids.
Nat Methods. 20(12):2034-2047Evolutionary conservation of embryonic DNA methylome remodelling in distantly related teleost species.
Show Preprint Nucleic Acids Res.Multi-chamber cardioids unravel human heart development and cardiac defects.
Cell. 186(25):5587-5605.e27EVI1 drives leukemogenesis through aberrant ERG activation.
Blood. 141(5):453-466SPOP targets the immune transcription factor IRF1 for proteasomal degradation.
Elife. 12HUWE1 controls tristetraprolin proteasomal degradation by regulating its phosphorylation.
Show Preprint Elife. 12Functionally distinct promoter classes initiate transcription via different mechanisms reflected in focused versus dispersed initiation patterns.
EMBO J. :e113519Integrated transcriptome and proteome analysis reveals posttranscriptional regulation of ribosomal genes in human brain organoids.
Elife. 12Artificial Insemination in Axolotl.
Methods Mol Biol. 2562:417-423Ascl1 and Ngn2 convert mouse embryonic stem cells to neurons via functionally distinct paths.
Nat Commun. 14(1):5341ZFP462 safeguards neural lineage specification by targeting G9A/GLP-mediated heterochromatin to silence enhancers.
Nat Cell Biol.A High-Sensitivity Low-Nanoflow LC-MS Configuration for High-Throughput Sample-Limited Proteomics.
Anal Chem. 95(51):18673-18678Panoramix SUMOylation on chromatin connects the piRNA pathway to the cellular heterochromatin machinery.
Nat Struct Mol Biol. 29(2):130-142The Sperm Protein Spaca6 is Essential for Fertilization in Zebrafish.
Show Preprint Front Cell Dev Biol. 9:806982DNA sequence and chromatin modifiers cooperate to confer epigenetic bistability at imprinting control regions.
Nat Genet.Targeted protein degradation: from small molecules to complex organelles-a Keystone Symposia report.
Ann N Y Acad Sci. 1510(1):79-99DeepSTARR predicts enhancer activity from DNA sequence and enables the de novo design of synthetic enhancers.
Nat Genet. 54(5):613-624MCM complexes are barriers that restrict cohesin-mediated loop extrusion.
Nature.The Axolotl's journey to the modern molecular era.
Curr Top Dev Biol. 147:631-658Amplification of human interneuron progenitors promotes brain tumors and neurological defects.
Science. 375(6579):eabf5546Canonical Wnt signaling and the regulation of divergent mesenchymal Fgf8 expression in axolotl limb development and regeneration.
Elife. 11The HUSH complex controls brain architecture and protocadherin fidelity.
Sci Adv. 8(44):eabo7247Potent Bactericidal Antimycobacterials Targeting the Chaperone ClpC1 Based on the Depsipeptide Natural Products Ecumicin and Ohmyungsamycin A.
J Med Chem. 65(6):4893-4908Developmental and housekeeping transcriptional programs in Drosophila require distinct chromatin remodelers.
Mol Cell. 82(19):3598-3612.e7Muscles are barely required for the patterning and cell dynamics in axolotl limb regeneration.
Front Genet. 13:1036641NMD is required for timely cell fate transitions by fine-tuning gene expression and regulating translation.
Show Preprint Genes Dev. 36(5-6):348-367Moyamoya disease: diagnosis and interventions.
Lancet Neurol.Dysregulated RNA polyadenylation contributes to metabolic impairment in non-alcoholic fatty liver disease.
Nucleic Acids Res. 50(6):3379-3393The PAX5-JAK2 translocation acts as dual-hit mutation that promotes aggressive B-cell leukemia via nuclear STAT5 activation.
EMBO J. 41(7):e108397Protocol for Human Blastoids Modeling Blastocyst Development and Implantation.
J Vis Exp. (186)Biallelic PAX5 mutations cause hypogammaglobulinemia, sensorimotor deficits, and autism spectrum disorder.
J Exp Med. 219(9)Cryo-EM structure of the plant 26S proteasome.
Plant Commun. 3(3):100310Altered developmental programs and oriented cell divisions lead to bulky bones during salamander limb regeneration.
Nat Commun. 13(1):6949A Rapid, Highly Sensitive and Open-Access SARS-CoV-2 Detection Assay for Laboratory and Home Testing.
Show Preprint Front Mol Biosci. 9:801309Different Gene Sets Are Associated With Azacitidine Response In Vitro Versus in Myelodysplastic Syndrome Patients.
Hemasphere. 6(11):e792Inducible and tissue-specific cell labeling in Cre-ERT2 transgenic Xenopus lines.
Dev Growth Differ. 64(5):243-253Single-cell analyses of axolotl telencephalon organization, neurogenesis, and regeneration.
Science. 377(6610):eabp9262Mimicked synthetic ribosomal protein complex for benchmarking crosslinking mass spectrometry workflows.
Nat Commun. 13(1):3975BacPROTACs mediate targeted protein degradation in bacteria.
Show Preprint Cell. 185(13):2338-2353.e18Nucleome programming is required for the foundation of totipotency in mammalian germline development.
EMBO J. :e110600Cohesin mediates DNA loop extrusion and sister chromatid cohesion by distinct mechanisms
bioRxiv . 2022.09.23.509019Proteome-scale identification of transcriptional activators in human cells.
Mol Cell. 82(3):497-499Differential cofactor dependencies define distinct types of human enhancers.
Nature. 606(7913):406-413Sperm membrane proteins DCST1 and DCST2 are required for sperm-egg interaction in mice and fish.
Show Preprint Commun Biol. 5(1):332Gene and transgenics nomenclature for the laboratory axolotl-Ambystoma mexicanum.
Dev Dyn. 251(6):913-921Mechanism-based combination therapies for metastatic cancer.
Sci Transl Med. 14(655):eadd0887Tig1 regulates proximo-distal identity during salamander limb regeneration.
Nat Commun. 13(1):1141Positional Memory in Vertebrate Regeneration: A Century's Insights from the Salamander Limb.
Cold Spring Harb Perspect Biol. 14(6)Urinary Collectrin (TMEM27) as Novel Marker for Acute Kidney Injury.
Life (Basel). 12(9)Cornelia de Lange syndrome mutations in NIPBL can impair cohesin-mediated DNA loop extrusion.
Proc Natl Acad Sci U S A. 119(18):e2201029119Lysosomal enzyme trafficking factor LYSET enables nutritional usage of extracellular proteins.
Science. 378(6615):eabn5637BRD4 degradation blocks expression of MYC and multiple forms of stem cell resistance in Ph+ chronic myeloid leukemia.
Am J Hematol. 97(9):1215-1225DNA replication timing directly regulates the frequency of oncogenic chromosomal translocations.
Science. 377(6612):eabj5502Comprehensive CRISPR-Cas9 screen identifies factors which are important for plasmablast development.
Front Immunol. 13:979606Interferons reshape the 3D conformation and accessibility of macrophage chromatin.
iScience. 25(3):103840The specialist in regeneration-the Axolotl-a suitable model to study bone healing?
NPJ Regen Med. 7(1):35SMC complexes can traverse physical roadblocks bigger than their ring size.
Show Preprint Cell Rep. 41(3):111491Visualizing maturation factor extraction from the nascent ribosome by the AAA-ATPase Drg1.
Nat Struct Mol Biol. 29(9):942-953Sororin is an evolutionary conserved antagonist of WAPL
bioRxiv . 2022.10.24.513534Bhlhe40 function in activated B and TFH cells restrains the GC reaction and prevents lymphomagenesis.
J Exp Med. 219(2)An allosteric HTRA1-calpain 2 complex with restricted activation profile.
Proc Natl Acad Sci U S A. 119(14):e2113520119Somatic hypermutation spectra are independent of the local transcriptional and epigenetic landscape
bioRxiv . 2022.05.21.492925Deep Proteome Profiling with Reduced Carryover Using Superficially Porous Microfabricated nanoLC Columns.
Anal Chem.A self-generated Toddler gradient guides mesodermal cell migration.
Show Preprint Sci Adv. 8(37):eadd2488Gruffi: an algorithm for computational removal of stressed cells from brain organoid transcriptomic datasets.
EMBO J. :e111118Structural basis of mRNA maturation: Time to put it together.
Curr Opin Struct Biol. 75:102431Discovery of potent and selective HER2 inhibitors with efficacy against HER2 exon 20 insertion-driven tumors, which preserve wild-type EGFR signaling.
Nat Cancer. 3(7):821-836The Xbp1-regulated transcription factor Mist1 restricts antibody secretion by restraining Blimp1 expression in plasma cells.
Front Immunol. 13:859598SCON-a Short Conditional intrON for conditional knockout with one-step zygote injection.
Show Preprint Exp Mol Med.Deep Single-Shot NanoLC-MS Proteome Profiling with a 1500 Bar UHPLC System, Long Fully Porous Columns, and HRAM MS.
J Proteome Res. 21(10):2545-2551Hierarchical regulation of the resting and activated T cell epigenome by major transcription factor families.
Nat Immunol. 23(1):122-134E3 ubiquitin ligase RNF213 employs a non-canonical zinc finger active site and is allosterically regulated by ATP
bioRxiv. 2021.05.10.443411Gaze mechanisms enabling the detection of faint stars in the night sky.
Eur J Neurosci. 54(4):5357-5367PHF3 regulates neuronal gene expression through the Pol II CTD reader domain SPOC.
Nat Commun. 12(1):6078The oxidoreductase PYROXD1 uses NAD(P)+ as an antioxidant to sustain tRNA ligase activity in pre-tRNA splicing and unfolded protein response.
Mol Cell. 81(12):2520-2532.e16The expression, localisation and interactome of pigeon CRY2.
Sci Rep. 11(1):20293The cellular and signaling dynamics of salamander limb regeneration.
Curr Opin Cell Biol. 73:117-123Cohesin mediates DNA loop extrusion by a "swing and clamp" mechanism.
Cell. 184(21):5448-5464.e22Functional Analysis of Non-Genetic Resistance to Platinum in Epithelial Ovarian Cancer Reveals a Role for the MBD3-NuRD Complex in Resistance Development.
Cancers (Basel). 13(15)Visualization of loop extrusion by DNA nanoscale tracing in single human cells
bioRxiv . 2021.04.12.439407Systematic refinement of gene annotations by parsing mRNA 3' end sequencing datasets.
Methods Enzymol. 655:205-223Cdc4 phospho-degrons allow differential regulation of Ame1CENP-U protein stability across the cell cycle.
Elife. 10Down-regulation of A20 promotes immune escape of lung adenocarcinomas.
Sci Transl Med. 13(601)Zebrafish Ski7 tunes RNA levels during the oocyte-to-embryo transition.
PLoS Genet. 17(2):e1009390Pax5 regulates B cell immunity by promoting PI3K signaling via PTEN down-regulation.
Sci Immunol. 6(61)Quality standards in proteomics research facilities: Common standards and quality procedures are essential for proteomics facilities and their users.
EMBO Rep. 22(6):e52626Comparative proteome signatures of trace samples by multiplexed Data-Independent Acquisition.
Mol Cell Proteomics. :100177Quantitative Accuracy and Precision in Multiplexed Single-Cell Proteomics.
Anal Chem.Spatiotemporal control of cell cycle acceleration during axolotl spinal cord regeneration.
Elife. 10Genome folding through loop extrusion by SMC complexes.
Nat Rev Mol Cell Biol. 22(7):445-464AKIRIN2 controls the nuclear import of proteasomes in vertebrates.
Nature. 599(7885):491-496The Fertilization Enigma: How Sperm and Egg Fuse.
Annu Rev Cell Dev Biol.Inhibition of CBP synergizes with the RNA-dependent mechanisms of Azacitidine by limiting protein synthesis.
Nat Commun. 12(1):6060MS Amanda 2.0: Advancements in the standalone implementation.
Rapid Commun Mass Spectrom. 35(11):e9088Ubiquitylation of MYC couples transcription elongation with double-strand break repair at active promoters.
Mol Cell. 81(4):830-844.e13Metabolic regulation by PPARγ is required for IL-33-mediated activation of ILC2s in lung and adipose tissue.
Mucosal Immunol. 14(3):585-593The conserved fertility factor SPACA4/Bouncer has divergent modes of action in vertebrate fertilization.
Show Preprint Proc Natl Acad Sci U S A. 118(39)Reciprocal zebrafish-medaka hybrids reveal maternal control of zygotic genome activation timing
bioRxiv . 2021.11.03.467109Limited access to antigen drives generation of early B cell memory while restraining the plasmablast response.
Immunity. 54(9):2005-2023.e10HUWE1 employs a giant substrate-binding ring to feed and regulate its HECT E3 domain.
Nat Chem Biol.Central amygdala circuit dynamics underlying the benzodiazepine anxiolytic effect.
Mol Psychiatry. 26(2):534-544Maternally-inherited anti-sense piRNAs antagonize transposon expression in teleost embryos
bioRxiv . 2021.11.03.467172miR-1 sustains muscle physiology by controlling V-ATPase complex assembly.
Sci Adv. 7(42):eabh1434Acquired resistance to anti-MAPK targeted therapy confers an immune-evasive tumor microenvironment and cross-resistance to immunotherapy in melanoma
Nature Cancer . 2:693–708Acquired resistance to anti-MAPK targeted therapy confers an immune-evasive tumor microenvironment and cross-resistance to immunotherapy in melanoma.
Nat Cancer. 2(7):693-708A crucial role for Jagunal homolog 1 in humoral immunity and antibody glycosylation in mice and humans.
J Exp Med. 218(1)McsB forms a gated kinase chamber to mark aberrant bacterial proteins for degradation.
Show Preprint Elife. 10Cardioids reveal self-organizing principles of human cardiogenesis.
Cell. 184(12):3299-3317.e22Identification of lectin receptors for conserved SARS-CoV-2 glycosylation sites.
EMBO J. :e108375MSX2 safeguards syncytiotrophoblast fate of human trophoblast stem cells.
Proc Natl Acad Sci U S A. 118(37)Human blastoids model blastocyst development and implantation.
Nature.Head-to-head comparison of direct-input RT-PCR and RT-LAMP against RT-qPCR on extracted RNA for rapid SARS-CoV-2 diagnostics.
medRxiv. 2021.01.19.21250079Concepts and functions of small RNA pathways in C. elegans.
Curr Top Dev Biol. 144:45-89Results of WICOVIR Gargle Pool PCR Testing in German Schools Based on the First 100,000 Tests.
Front Pediatr. 9:721518Organoid modeling of Zika and herpes simplex virus 1 infections reveals virus-specific responses leading to microcephaly.
Cell Stem Cell. 28(8):1362-1379.e7Targeting CD56 with an antibody-drug conjugate in Merkel cell carcinoma.
Br J Dermatol.Fibroblast dedifferentiation as a determinant of successful regeneration.
Dev Cell. 56(10):1541-1551.e6A genome-wide CRISPR/Cas9 screen to identify phagocytosis modulators in monocytic THP-1 cells.
Sci Rep. 11(1):12973Toward whole tissue imaging of axolotl regeneration.
Dev Dyn. 250(6):800-806Cleavable Cross-Linkers and Mass Spectrometry for the Ultimate Task of Profiling Protein-Protein Interaction Networks in Vivo.
J Proteome Res. 20(1):78-93Giant lungfish genome elucidates the conquest of land by vertebrates.
Nature. 590(7845):284-289Substrate-engaged type III secretion system structures reveal gating mechanism for unfolded protein translocation.
Nat Commun. 12(1):1546RANK links thymic regulatory T cells to fetal loss and gestational diabetes in pregnancy.
Nature. 589(7842):442-447Rapid nucleus-scale reorganization of chromatin in neurons enables transcriptional adaptation for memory consolidation.
PLoS One. 16(5):e0244038How DNA loop extrusion mediated by cohesin enables V(D)J recombination.
Curr Opin Cell Biol. 70:75-83DNA replication timing directly regulates the frequency of oncogenic chromosomal translocations
bioRxiv . 2021.05.29.446276A functional LSD1 coregulator screen reveals a novel transcriptional regulatory cascade connecting R-loop homeostasis with epigenetic regulation.
Nucleic Acids Res. 49(8):4350-4370MS Annika: A New Cross-Linking Search Engine.
J Proteome Res. 20(5):2560-2569Structural basis for inhibition of the AAA-ATPase Drg1 by diazaborine.
Nat Commun. 12(1):3483The linear ubiquitin chain assembly complex (LUBAC) generates heterotypic ubiquitin chains.
Show Preprint Elife. 10Structure of the peripheral arm of a minimalistic respiratory complex I.
Structure.The giant axolotl genome uncovers the evolution, scaling, and transcriptional control of complex gene loci.
Proc Natl Acad Sci U S A. 118(15)Molecular principles of Piwi-mediated cotranscriptional silencing through the dimeric SFiNX complex.
Genes Dev. 35(5-6):392-409Insights into gene regulation: From regulatory genomic elements to DNA-protein and protein-protein interactions.
Curr Opin Cell Biol. 70:58-66Selective Requirement of MYB for Oncogenic Hyperactivation of a Translocated Enhancer in Leukemia.
Cancer Discov. 11(11):2868-2883Ultrasensitive NanoLC-MS of Subnanogram Protein Samples Using Second Generation Micropillar Array LC Technology with Orbitrap Exploris 480 and FAIMS PRO.
Anal Chem. 93(25):8704-8710Self-organized cell migration across scales - from single cell movement to tissue formation.
Development. 148(7)Isolating live cell clones from barcoded populations using CRISPRa-inducible reporters.
Nat Biotechnol. 39(2):174-178Precision Medicine in Hematology 2021: Definitions, Tools, Perspectives, and Open Questions.
Hemasphere. 5(3):e536Core-binding factor leukemia hijacks the T-cell-prone PU.1 antisense promoter.
Blood. 138(15):1345-1358Caenorhabditis elegans RMI2 functional homolog-2 (RMIF-2) and RMI1 (RMH-1) have both overlapping and distinct meiotic functions within the BTR complex.
PLoS Genet. 17(7):e1009663GSK3-mediated phosphorylation of DEK3 regulates chromatin accessibility and stress tolerance in Arabidopsis.
FEBS J.Central amygdala circuitry modulates nociceptive processing through differential hierarchical interaction with affective network dynamics.
Commun Biol. 4(1):732Sensitivity and specificity of the antigen-based anterior nasal self-testing programme for detecting SARS-CoV-2 infection in schools, Austria, March 2021.
Euro Surveill. 26(34)Prevalence of RT-qPCR-detected SARS-CoV-2 infection at schools: First results from the Austrian School-SARS-CoV-2 prospective cohort study.
Lancet Reg Health Eur. 5:100086Cellular Control of Protein Turnover via the Modification of the Amino Terminus.
Int J Mol Sci. 22(7)Multiplexed detection of SARS-CoV-2 and other respiratory infections in high throughput by SARSeq.
Nat Commun. 12(1):3132Moyamoya disease factor RNF213 is a giant E3 ligase with a dynein-like core and a distinct ubiquitin-transfer mechanism.
Elife. 9MERTK-Dependent Ensheathment of Photoreceptor Outer Segments by Human Pluripotent Stem Cell-Derived Retinal Pigment Epithelium.
Stem Cell Reports. 14(3):374-389Correction: The Airn lncRNA does not require any DNA elements within its locus to silence distant imprinted genes.
PLoS Genet. 16(10):e1009151Native Mass Spectrometry Can Effectively Predict PROTAC Efficacy.
ACS Cent Sci. 6(7):1223-1230A synthetic peptide library for benchmarking crosslinking-mass spectrometry search engines for proteins and protein complexes.
Nat Commun. 11(1):742Proline-rich protein PRR19 functions with cyclin-like CNTD1 to promote meiotic crossing over in mouse.
Nat Commun. 11(1):3101Leukemia Cell of Origin Influences Apoptotic Priming and Sensitivity to LSD1 Inhibition.
Cancer Discov. 10(10):1500-1513The EMT modulator SNAI1 contributes to AML pathogenesis via its interaction with LSD1.
Blood. 136(8):957-973Combinatorial Action of Temporally Segregated Transcription Factors.
Dev Cell. 55(4):483-499.e7MicroRNAs: From Mechanism to Organism.
Front Cell Dev Biol. 8:409Two MicroRNAs Are Sufficient for Embryonic Patterning in C. elegans.
Curr Biol. 30(24):5058-5065.e5A human tissue screen identifies a regulator of ER secretion as a brain-size determinant.
Science. 370(6519):935-941Site-specific ubiquitination of the E3 ligase HOIP regulates apoptosis and immune signaling.
EMBO J. 39(24):e103303Unsupervised learning of control signals and their encodings in Caenorhabditis elegans whole-brain recordings.
J R Soc Interface. 17(173):20200459Author Correction: Olfaction regulates organismal proteostasis and longevity via microRNA-dependent signalling.
Nat Metab. 2(1):126Spt5-mediated enhancer transcription directly couples enhancer activation with physical promoter interaction.
Nat Genet. 52(5):505-515A Data Structure for Real-Time Aggregation Queries of Big Brain Networks.
Neuroinformatics. 18(1):131-149Reduced replication origin licensing selectively kills KRAS-mutant colorectal cancer cells via mitotic catastrophe.
Cell Death Dis. 11(7):499Species-specific mechanisms during fertilization.
Curr Top Dev Biol. 140:121-144Wapl repression by Pax5 promotes V gene recombination by Igh loop extrusion.
Nature. 584(7819):142-147The biophysical, molecular, and anatomical landscape of pigeon CRY4: A candidate light-based quantal magnetosensor.
Sci Adv. 6(33):eabb9110Nested Neuronal Dynamics Orchestrate a Behavioral Hierarchy across Timescales.
Neuron. 105(3):562-576.e9Brain-wide representations of ongoing behavior: a universal principle?
Curr Opin Neurobiol. 64:60-69The amygdala instructs insular feedback for affective learning.
Elife. 9SFPQ Depletion Is Synthetically Lethal with BRAFV600E in Colorectal Cancer Cells.
Cell Rep. 32(12):108184HACE1 Prevents Lung Carcinogenesis via Inhibition of RAC-Family GTPases.
Cancer Res. 80(14):3009-3022DigiTAG-a RNA Sequencing Approach to Analyze Transcriptomes of Rare Cell Populations in Drosophila melanogaster.
Bio Protoc. 10(21):e3809The H3 histone chaperone NASPSIM3 escorts CenH3 in Arabidopsis.
Plant J. 101(1):71-86A proteomic survey of microtubule-associated proteins in a R402H TUBA1A mutant mouse.
PLoS Genet. 16(11):e1009104LSD1 inhibition induces differentiation and cell death in Merkel cell carcinoma.
EMBO Mol Med. 12(11):e12525Cerebellar Neurodynamics Predict Decision Timing and Outcome on the Single-Trial Level.
Cell. 180(3):536-551.e17Repression of the B cell identity factor Pax5 is not required for plasma cell development.
J Exp Med. 217(11)Neuronal circuits and the magnetic sense: central questions.
J Exp Biol. 223(Pt 21)Ubiquitin chain-elongating enzyme UBE2S activates the RING E3 ligase APC/C for substrate priming.
Nat Struct Mol Biol. 27(6):550-560AMPK leads to phosphorylation of the transcription factor Nrf2, tuning transactivation of selected target genes.
Redox Biol. 29:101393Fast and Highly Efficient Affinity Enrichment of Azide-A-DSBSO Cross-Linked Peptides.
J Proteome Res. 19(5):2071-2079Activation by substoichiometric inhibition.
Proc Natl Acad Sci U S A. 117(3):1414-1418Bile canaliculi remodeling activates YAP via the actin cytoskeleton during liver regeneration.
Mol Syst Biol. 16(2):e8985Multilayered VBC score predicts sgRNAs that efficiently generate loss-of-function alleles.
Nat Methods. 17(7):708-716Conformation of sister chromatids in the replicated human genome.
Nature. 586(7827):139-144PDS5 proteins are required for proper cohesin dynamics and participate in replication fork protection.
J Biol Chem. 295(1):146-157A high sensitivity ZENK monoclonal antibody to map neuronal activity in Aves.
Sci Rep. 10(1):915Introducing www.axolotl-omics.org - an integrated -omics data portal for the axolotl research community.
Exp Cell Res. 394(1):112143Identification of ALK in Thinness.
Cell. 181(6):1246-1262.e22A versatile depigmentation, clearing, and labeling method for exploring nervous system diversity.
Sci Adv. 6(22):eaba0365Calcium modulates the domain flexibility and function of an α-actinin similar to the ancestral α-actinin.
Proc Natl Acad Sci U S A. 117(36):22101-22112ANGEL2 is a member of the CCR4 family of deadenylases with 2',3'-cyclic phosphatase activity.
Science. 369(6503):524-530Stress peptides sensitize fear circuitry to promote passive coping.
Mol Psychiatry. 25(2):428-441Structure of the human core transcription-export complex reveals a hub for multivalent interactions.
Elife. 9Inducible knock-out of BCL6 in lymphoma cells results in tumor stasis.
Oncotarget. 11(9):875-890CDK6 is an essential direct target of NUP98 fusion proteins in acute myeloid leukemia.
Blood. 136(4):387-400A Human Retinal Pigment Epithelium-Based Screening Platform Reveals Inducers of Photoreceptor Outer Segments Phagocytosis.
Stem Cell Reports. 15(6):1347-1361Wapl releases Scc1-cohesin and regulates chromosome structure and segregation in mouse oocytes.
J Cell Biol. 219(4)Quantifying the heterogeneity of macromolecular machines by mass photometry.
Nat Commun. 11(1):1772Oral and Palatal Dentition of Axolotl Arises From a Common Tooth-Competent Zone Along the Ecto-Endodermal Boundary.
Front Cell Dev Biol. 8:622308A cross-kingdom conserved ER-phagy receptor maintains endoplasmic reticulum homeostasis during stress.
Elife. 9Cohesin-Dependent and -Independent Mechanisms Mediate Chromosomal Contacts between Promoters and Enhancers.
Cell Rep. 32(3):107929STAG1 vulnerabilities for exploiting cohesin synthetic lethality in STAG2-deficient cancers.
Life Sci Alliance. 3(7)ESCO1 and CTCF enable formation of long chromatin loops by protecting cohesinSTAG1 from WAPL.
Elife. 9Structure-function analysis of microRNA 3'-end trimming by Nibbler.
Proc Natl Acad Sci U S A. 117(48):30370-30379Parallel PRC2/cPRC1 and vPRC1 pathways silence lineage-specific genes and maintain self-renewal in mouse embryonic stem cells.
Sci Adv. 6(14):eaax5692The transcription factor odd-paired regulates temporal identity in transit-amplifying neural progenitors via an incoherent feed-forward loop.
Elife. 8The Airn lncRNA does not require any DNA elements within its locus to silence distant imprinted genes.
PLoS Genet. 15(7):e1008268The nascent RNA binding complex SFiNX licenses piRNA-guided heterochromatin formation.
Nat Struct Mol Biol. 26(8):720-731Precocious expression of Blimp1 in B cells causes autoimmune disease with increased self-reactive plasma cells.
EMBO J. 38(2)Topoisomerase II-Induced Chromosome Breakage and Translocation Is Determined by Chromosome Architecture and Transcriptional Activity.
Mol Cell. 75(2):252-266.e8Publisher Correction: The metabolite BH4 controls T cell proliferation in autoimmunity and cancer.
Nature. 572(7769):E18The Prrx1 limb enhancer marks an adult subpopulation of injury-responsive dermal fibroblasts.
Biol Open. 8(7)DNA loop extrusion by human cohesin.
Science. 366(6471):1338-1345apQuant: Accurate Label-Free Quantification by Quality Filtering.
J Proteome Res. 18(1):535-541Cryptic activation of an Irf8 enhancer governs cDC1 fate specification.
Nat Immunol. 20(9):1161-1173Publisher Correction: Application and optimization of CRISPR-Cas9-mediated genome engineering in axolotl (Ambystoma mexicanum).
Nat Protoc. 14(8):2597Olfaction regulates organismal proteostasis and longevity via microRNA-dependent signalling
Nature Metabolism. 1:350–359BrainTrawler: A visual analytics framework for iterative exploration of heterogeneous big brain data
Computer & Graphics. 82:304-320Spectral Clustering Improves Label-Free Quantification of Low-Abundant Proteins.
J Proteome Res. 18(4):1477-1485Allies or Enemies-The Multifaceted Role of Myeloid Cells in the Tumor Microenvironment.
Front Immunol. 10:2746Transcriptional cofactors display specificity for distinct types of core promoters.
Nature. 570(7759):122-126Estrogen Signaling Drives Ciliogenesis in Human Endometrial Organoids.
Endocrinology. 160(10):2282-2297Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin.
Nat Commun. 10(1):4781Functional-genetic approaches to understanding drug response and resistance.
Curr Opin Genet Dev. 54:41-47Shaping Striated Muscles with Ubiquitin Proteasome System in Health and Disease.
Trends Mol Med. 25(9):760-774Absolute quantification of cohesin, CTCF and their regulators in human cells.
Elife. 8Evolution of neuronal anatomy and circuitry in two highly divergent nematode species.
Elife. 8First Community-Wide, Comparative Cross-Linking Mass Spectrometry Study.
Anal Chem. 91(11):6953-6961Selective Roles of Vertebrate PCF11 in Premature and Full-Length Transcript Termination.
Mol Cell. 74(1):158-172.e9Werner syndrome helicase is a selective vulnerability of microsatellite instability-high tumor cells.
Elife. 8A Comparative Perspective on Brain Regeneration in Amphibians and Teleost Fish.
Dev Neurobiol. 79(5):424-436No evidence for a magnetite-based magnetoreceptor in the lagena of pigeons.
Curr Biol. 29(1):R14-R15Broad applicability of a streamlined ethyl cinnamate-based clearing procedure.
Development. 146(3)Sequencing cell-type-specific transcriptomes with SLAM-ITseq.
Nat Protoc. 14(8):2261-2278Publisher Correction: Sequencing cell-type-specific transcriptomes with SLAM-ITseq.
Nat Protoc. 14(8):2597Interconversion between Tumorigenic and Differentiated States in Acute Myeloid Leukemia.
Cell Stem Cell. 25(2):258-272.e9A kinase-independent role for CDK8 in BCR-ABL1+ leukemia.
Nat Commun. 10(1):4741Quantification of experimentally induced nucleotide conversions in high-throughput sequencing datasets.
BMC Bioinformatics. 20(1):258STARR-seq and UMI-STARR-seq: Assessing Enhancer Activities for Genome-Wide-, High-, and Low-Complexity Candidate Libraries.
Curr Protoc Mol Biol. 128(1):e105The histone chaperone CAF-1 cooperates with the DNA methyltransferases to maintain Cd4 silencing in cytotoxic T cells.
Genes Dev. 33(11-12):669-683All-trans retinoic acid enhances, and a pan-RAR antagonist counteracts, the stem cell promoting activity of EVI1 in acute myeloid leukemia.
Cell Death Dis. 10(12):944A Putative Mechanism for Magnetoreception by Electromagnetic Induction in the Pigeon Inner Ear.
Curr Biol. 29(23):4052-4059.e4SGLT2 inhibition and renal urate excretion: role of luminal glucose, GLUT9, and URAT1.
Am J Physiol Renal Physiol. 316(1):F173-F185Mouse ANKRD31 Regulates Spatiotemporal Patterning of Meiotic Recombination Initiation and Ensures Recombination between X and Y Sex Chromosomes.
Mol Cell. 74(5):1069-1085.e11Tinbergen's challenge for the neuroscience of behavior.
Proc Natl Acad Sci U S A. 116(20):9704-9710Structural Basis of Nuclear pre-mRNA Splicing: Lessons from Yeast.
Cold Spring Harb Perspect Biol. 11(5)A molecular switch from STAT2-IRF9 to ISGF3 underlies interferon-induced gene transcription.
Nat Commun. 10(1):2921Structural and Functional Analyses of the Human PDH Complex Suggest a "Division-of-Labor" Mechanism by Local E1 and E3 Clusters.
Structure. 27(7):1124-1136.e4Bhlhe40 and Bhlhe41 transcription factors regulate alveolar macrophage self-renewal and identity.
EMBO J. 38(19):e101233Structural analysis of urinary light chains and proteomic analysis of hyaline tubular casts in light chain associated kidney disorders.
PeerJ. 7:e7819A role for miR-132 in learned safety.
Sci Rep. 9(1):528Endosome and Golgi-associated degradation (EGAD) of membrane proteins regulates sphingolipid metabolism.
EMBO J. 38(15):e101433Ikaros prevents autoimmunity by controlling anergy and Toll-like receptor signaling in B cells.
Nat Immunol. 20(11):1517-1529MTHFD1 interaction with BRD4 links folate metabolism to transcriptional regulation.
Nat Genet. 51(6):990-998Self-organization of parS centromeres by the ParB CTP hydrolase.
Science. 366(6469):1129-1133Improved Sensitivity in Low-Input Proteomics Using Micropillar Array-Based Chromatography.
Anal Chem. 91(22):14203-14207Optimized Fragmentation Improves the Identification of Peptides Cross-Linked by MS-Cleavable Reagents.
J Proteome Res. 18(3):1363-1370Structure of McsB, a protein kinase for regulated arginine phosphorylation.
Nat Chem Biol. 15(5):510-518Spectral recording of gene expression history by fluorescent timer protein.
Biotechniques. 67(4):154-164Apelin inhibition prevents resistance and metastasis associated with anti-angiogenic therapy.
EMBO Mol Med. 11(8):e9266Integrative analysis of pooled CRISPR genetic screens using MAGeCKFlute.
Nat Protoc. 14(3):756-780Posing the APC/C E3 Ubiquitin Ligase to Orchestrate Cell Division.
Trends Cell Biol. 29(2):117-134Protein engineering of a ubiquitin-variant inhibitor of APC/C identifies a cryptic K48 ubiquitin chain binding site.
Proc Natl Acad Sci U S A. 116(35):17280-17289Volumetric Ca2+ Imaging in the Mouse Brain Using Hybrid Multiplexed Sculpted Light Microscopy.
Cell. 177(4):1050-1066.e14Human blood vessel organoids as a model of diabetic vasculopathy.
Nature. 565(7740):505-510A novel approach to immunoapheresis of C3a/C3 and proteomic identification of associates.
PeerJ. 7:e8218N-terminal β-strand underpins biochemical specialization of an ATG8 isoform.
PLoS Biol. 17(7):e3000373Pooled Generation of Lentiviral Tetracycline-Regulated microRNA Embedded Short Hairpin RNA Libraries.
Hum Gene Ther Methods. 29(1):16-29Cell-type specific sequencing of microRNAs from complex animal tissues.
Nat Methods. 15(4):283-289A high-throughput method to identify trans-activation domains within transcription factor sequences.
EMBO J. 37(16)Epigenetic regulation of brain region-specific microglia clearance activity.
Nat Neurosci. 21(8):1049-1060CDK6 Antagonizes p53-Induced Responses during Tumorigenesis.
Cancer Discov. 8(7):884-897Human tripartite motif protein 52 is required for cell context-dependent proliferation.
Oncotarget. 9(17):13565-13581Experimental and computational framework for a dynamic protein atlas of human cell division.
Nature. 561(7723):411-415Assessing sufficiency and necessity of enhancer activities for gene expression and the mechanisms of transcription activation.
Genes Dev. 32(3-4):202-223Coordinated Control of mRNA and rRNA Processing Controls Embryonic Stem Cell Pluripotency and Differentiation.
Cell Stem Cell. 22(4):543-558.e12The metabolite BH4 controls T cell proliferation in autoimmunity and cancer.
Nature. 563(7732):564-568CharmeRT: Boosting Peptide Identifications by Chimeric Spectra Identification and Retention Time Prediction.
J Proteome Res. 17(8):2581-2589PhoStar: Identifying Tandem Mass Spectra of Phosphorylated Peptides before Database Search.
J Proteome Res. 17(1):290-295The IAP family member BRUCE regulates autophagosome-lysosome fusion.
Nat Commun. 9(1):599Lidocaine is a nocebo treatment for trigeminally mediated magnetic orientation in birds.
J R Soc Interface. 15(145)Application and optimization of CRISPR-Cas9-mediated genome engineering in axolotl (Ambystoma mexicanum).
Nat Protoc. 13(12):2908-2943Regulation of RNA polymerase II processivity by Spt5 is restricted to a narrow window during elongation.
EMBO J. 37(8)Polycomb repression complex 2 is required for the maintenance of retinal progenitor cells and balanced retinal differentiation.
Dev Biol. 433(1):47-60Predicting functional neuroanatomical maps from fusing brain networks with genetic information.
Neuroimage. 170:113-120Single-cell analysis uncovers convergence of cell identities during axolotl limb regeneration.
Science. 362(6413)The novel BET bromodomain inhibitor BI 894999 represses super-enhancer-associated transcription and synergizes with CDK9 inhibition in AML.
Oncogene. 37(20):2687-2701Dorsal tegmental dopamine neurons gate associative learning of fear.
Nat Neurosci. 21(7):952-962Mutations in Vps15 perturb neuronal migration in mice and are associated with neurodevelopmental disease in humans.
Nat Neurosci. 21(2):207-217Publisher Correction: Mutations in Vps15 perturb neuronal migration in mice and are associated with neurodevelopmental disease in humans.
Nat Neurosci. 21(8):1139A new era of proactive melanoma therapy: hit hard, hit early.
Br J Dermatol. 178(4):817-820Eukaryotic core promoters and the functional basis of transcription initiation.
Nat Rev Mol Cell Biol. 19(10):621-637Self-Renewing Trophoblast Organoids Recapitulate the Developmental Program of the Early Human Placenta.
Stem Cell Reports. 11(2):537-551Structure and Conformational Dynamics of the Human Spliceosomal Bact Complex.
Cell. 172(3):454-464.e11UFD-2 is an adaptor-assisted E3 ligase targeting unfolded proteins.
Nat Commun. 9(1):484The Ly6/uPAR protein Bouncer is necessary and sufficient for species-specific fertilization.
Science. 361(6406):1029-1033Improved Genome Assembly and Annotation for the Rock Pigeon (Columba livia).
G3 (Bethesda). 8(5):1391-1398The replicative helicase MCM recruits cohesin acetyltransferase ESCO2 to mediate centromeric sister chromatid cohesion.
EMBO J. 37(15)Sensorimotor integration in Caenorhabditis elegans: a reappraisal towards dynamic and distributed computations.
Philos Trans R Soc Lond B Biol Sci. 373(1758)Sensorimotor Integration for Decision Making: How the Worm Steers.
Neuron. 97(2):258-260Control of B-1a cell development by instructive BCR signaling.
Curr Opin Immunol. 51:24-31Cryptochrome: The magnetosensor with a sinister side?
PLoS Biol. 16(10):e3000018Comment on "Magnetosensitive neurons mediate geomagnetic orientation in Caenorhabditis elegans".
Elife. 7Ectopic otoconial formation in the lagena of the pigeon inner ear.
Biol Open. 7(8)SLAM-ITseq: sequencing cell type-specific transcriptomes without cell sorting.
Development. 145(13)Signaling-Dependent Control of Apical Membrane Size and Self-Renewal in Rosette-Stage Human Neuroepithelial Stem Cells.
Stem Cell Reports. 10(6):1751-1765Senescence-associated reprogramming promotes cancer stemness.
Nature. 553(7686):96-100CD44 is a RAS/STAT5-regulated invasion receptor that triggers disease expansion in advanced mastocytosis.
Blood. 132(18):1936-1950Resolving systematic errors in widely used enhancer activity assays in human cells.
Nat Methods. 15(2):141-149SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis.
Science. 360(6390):800-805The axolotl genome and the evolution of key tissue formation regulators.
Nature. 554(7690):50-55Author Correction: The axolotl genome and the evolution of key tissue formation regulators.
Nature. 559(7712):E2Pseudotyped baculovirus is an effective gene expression tool for studying molecular function during axolotl limb regeneration.
Dev Biol. 433(2):262-275Structural prediction of protein models using distance restraints derived from cross-linking mass spectrometry data.
Nat Protoc. 13(3):478-494Reply to 'Defining distance restraints in HADDOCK'.
Nat Protoc. 13(7):1503-1505Author Correction: Structural prediction of protein models using distance restraints derived from cross-linking mass spectrometry data.
Nat Protoc. 13(7):1724Affinity proteomics reveals extensive phosphorylation of the Brassica chromosome axis protein ASY1 and a network of associated proteins at prophase I of meiosis.
Plant J. 93(1):17-33Drug-induced inhibition of phosphorylation of STAT5 overrides drug resistance in neoplastic mast cells.
Leukemia. 32(4):1016-1022Prespliceosome structure provides insights into spliceosome assembly and regulation.
Nature. 559(7714):419-422Behavioral Assays to Study Oxygen and Carbon Dioxide Sensing in Caenorhabditis elegans.
Bio Protoc. 8(1)A programmable platform for sub-second multichemical dynamic stimulation and neuronal functional imaging in C. elegans.
Lab Chip. 18(3):505-513Mutations that prevent methylation of cohesin render sensitivity to DNA damage in S. pombe.
J Cell Sci. 131(13)Necroptosis microenvironment directs lineage commitment in liver cancer.
Nature. 562(7725):69-75Analysis of chromosomes from mouse oocytes and mammalian cultured cells by light microscopy.
Methods Cell Biol. 144:287-305High-speed volumetric imaging of neuronal activity in freely moving rodents.
Nat Methods. 15(6):429-432Author Correction: High-speed volumetric imaging of neuronal activity in freely moving rodents.
Nat Methods. 15(6):469Energy Scarcity Promotes a Brain-wide Sleep State Modulated by Insulin Signaling in C. elegans.
Cell Rep. 22(4):953-966MLL-fusion-driven leukemia requires SETD2 to safeguard genomic integrity.
Nat Commun. 9(1):1983An extracellular network of Arabidopsis leucine-rich repeat receptor kinases.
Nature. 553(7688):342-346Analysis of PNGase F-Resistant N-Glycopeptides Using SugarQb for Proteome Discoverer 2.1 Reveals Cryptic Substrate Specificities.
Proteomics. 18(13):e1700436Dynamics of sister chromatid resolution during cell cycle progression.
J Cell Biol. 217(6):1985-2004The RNA helicase DDX3X is an essential mediator of innate antimicrobial immunity.
PLoS Pathog. 14(11):e1007397Mutations in MAST1 Cause Mega-Corpus-Callosum Syndrome with Cerebellar Hypoplasia and Cortical Malformations.
Neuron. 100(6):1354-1368.e5A Guide to Emerging Technologies for Large-Scale and Whole-Brain Optical Imaging of Neuronal Activity.
Annu Rev Neurosci. 41:431-452Expressing Multi-subunit Complexes Using biGBac.
Methods Mol Biol. 1764:329-343Time-resolved transcriptomics in neural stem cells identifies a v-ATPase/Notch regulatory loop.
J Cell Biol. 217(9):3285-3300TCEA1 regulates the proliferative potential of mouse myeloid cells.
Exp Cell Res. 370(2):551-560Coupling shRNA screens with single-cell RNA-seq identifies a dual role for mTOR in reprogramming-induced senescence.
Genes Dev. 31(20):2085-2098An optimized lentiviral vector system for conditional RNAi and efficient cloning of microRNA embedded short hairpin RNA libraries.
Biomaterials. 139:102-115A framework for understanding the roles of miRNAs in animal development.
Development. 144(14):2548-2559Mapping the mouse Allelome reveals tissue-specific regulation of allelic expression.
Elife. 6Genome-wide assessment of sequence-intrinsic enhancer responsiveness at single-base-pair resolution.
Nat Biotechnol. 35(2):136-144Structure of the mycobacterial ESX-5 type VII secretion system membrane complex by single-particle analysis.
Nat Microbiol. 2:17047Brain-specific knockin of the pathogenic Tubb5 E401K allele causes defects in motor coordination and prepulse inhibition.
Behav Brain Res. 323:47-55Tubulins and brain development - The origins of functional specification.
Mol Cell Neurosci. 84:58-67Uner Tan syndrome caused by a homozygous TUBB2B mutation affecting microtubule stability.
Hum Mol Genet. 26(2):258-269Cohesin is positioned in mammalian genomes by transcription, CTCF and Wapl.
Nature. 544(7651):503-507Promoting transcription over long distances.
Nat Genet. 49(7):972-973A Novel Strategy Combining Array-CGH, Whole-exome Sequencing and In Utero Electroporation in Rodents to Identify Causative Genes for Brain Malformations.
J Vis Exp. (130)Root diffusion barrier control by a vasculature-derived peptide binding to the SGN3 receptor.
Science. 355(6322):280-284A reversible haploid mouse embryonic stem cell biobank resource for functional genomics.
Nature. 550(7674):114-118Efficient gene knockin in axolotl and its use to test the role of satellite cells in limb regeneration.
Proc Natl Acad Sci U S A. 114(47):12501-12506Probing the canonicity of the Wnt/Wingless signaling pathway.
PLoS Genet. 13(4):e1006700Loss of Apela Peptide in Mice Causes Low Penetrance Embryonic Lethality and Defects in Early Mesodermal Derivatives.
Cell Rep. 20(9):2116-2130A mechanism of cohesin-dependent loop extrusion organizes zygotic genome architecture.
EMBO J. 36(24):3600-3618CCL2 is a KIT D816V-dependent modulator of the bone marrow microenvironment in systemic mastocytosis.
Blood. 129(3):371-382Modeling Renal Cell Carcinoma in Mice: Bap1 and Pbrm1 Inactivation Drive Tumor Grade.
Cancer Discov. 7(8):900-917Inhibition of Pol I transcription treats murine and human AML by targeting the leukemia-initiating cell population.
Blood. 129(21):2882-2895Thiol-linked alkylation of RNA to assess expression dynamics.
Nat Methods. 14(12):1198-1204BET-Bromodomain Inhibitors Engage the Host Immune System and Regulate Expression of the Immune Checkpoint Ligand PD-L1.
Cell Rep. 18(9):2162-2174Loss-of-function genetic tools for animal models: cross-species and cross-platform differences.
Nat Rev Genet. 18(1):24-40Reconstitution of a Patterned Neural Tube from Single Mouse Embryonic Stem Cells.
Methods Mol Biol. 1597:43-55Tumor Trp53 status and genotype affect the bone marrow microenvironment in acute myeloid leukemia.
Oncotarget. 8(48):83354-83369Dissection of neuronal gap junction circuits that regulate social behavior in Caenorhabditis elegans.
Proc Natl Acad Sci U S A. 114(7):E1263-E1272Essential role for the transcription factor Bhlhe41 in regulating the development, self-renewal and BCR repertoire of B-1a cells.
Nat Immunol. 18(4):442-455STAT3 Regulation of Citrate Synthase Is Essential during the Initiation of Lymphocyte Cell Growth.
Cell Rep. 19(5):910-918CRISPR-UMI: single-cell lineage tracing of pooled CRISPR-Cas9 screens.
Nat Methods. 14(12):1191-1197Transcription elongation factors represent in vivo cancer dependencies in glioblastoma.
Nature. 547(7663):355-359A global brain state underlies C. elegans sleep behavior.
Science. 356(6344)Subcellular analysis of pigeon hair cells implicates vesicular trafficking in cuticulosome formation and maintenance.
Elife. 6Video rate volumetric Ca2+ imaging across cortex using seeded iterative demixing (SID) microscopy.
Nat Methods. 14(8):811-818Magnetoreception-A sense without a receptor.
PLoS Biol. 15(10):e2003234Toddler signaling regulates mesodermal cell migration downstream of Nodal signaling.
Elife. 6A right-handed signalling pathway drives heart looping in vertebrates.
Nature. 549(7670):86-90The crystal structure of Deg9 reveals a novel octameric-type HtrA protease.
Nat Plants. 3(12):973-982BubR1 Promotes Bub3-Dependent APC/C Inhibition during Spindle Assembly Checkpoint Signaling.
Curr Biol. 27(19):2915-2927.e7Urinary neprilysin in the critically ill patient.
BMC Nephrol. 18(1):172Polycomb protein RING1A limits hematopoietic differentiation in myelodysplastic syndromes.
Oncotarget. 8(70):115002-115017Prediction of potent shRNAs with a sequential classification algorithm.
Nat Biotechnol. 35(4):350-353RANK rewires energy homeostasis in lung cancer cells and drives primary lung cancer.
Genes Dev. 31(20):2099-2112Combinatorial function of transcription factors and cofactors.
Curr Opin Genet Dev. 43:73-81Phosphoproteomics with Activated Ion Electron Transfer Dissociation.
Anal Chem. 89(12):6367-6376Nodal patterning without Lefty inhibitory feedback is functional but fragile.
Elife. 6Non-model model organisms.
BMC Biol. 15(1):55DNA Cross-Bridging Shapes a Single Nucleus from a Set of Mitotic Chromosomes.
Cell. 170(5):956-972.e23A Zip3-like protein plays a role in crossover formation in the SC-less meiosis of the protist Tetrahymena.
Mol Biol Cell. 28(6):825-833BIME2, a novel gene required for interhomolog meiotic recombination in the protist model organism Tetrahymena.
Chromosome Res. 25(3-4):291-298Molecular role of the PAX5-ETV6 oncoprotein in promoting B-cell acute lymphoblastic leukemia.
EMBO J. 36(6):718-735Control of type III protein secretion using a minimal genetic system.
Nat Commun. 8:14737Comparative glycoproteomics of stem cells identifies new players in ricin toxicity.
Nature. 549(7673):538-542Virtual reality for freely moving animals.
Nat Methods. 14(10):995-1002A vital sugar code for ricin toxicity.
Cell Res. 27(11):1351-1364Salamander spinal cord regeneration: The ultimate positive control in vertebrate spinal cord regeneration.
Dev Biol. 432(1):63-71Histone Acetyltransferase Activity of MOF Is Required for MLL-AF9 Leukemogenesis.
Cancer Res. 77(7):1753-1762Synthetic lethality between the cohesin subunits STAG1 and STAG2 in diverse cancer contexts.
Elife. 6Proceedings of the EuBIC Winter School 2017.
J Proteomics. 161:78-80Topologically associating domains and chromatin loops depend on cohesin and are regulated by CTCF, WAPL, and PDS5 proteins.
EMBO J. 36(24):3573-3599Anabolism-Associated Mitochondrial Stasis Driving Lymphocyte Differentiation over Self-Renewal.
Cell Rep. 17(12):3142-3152NK Cell-Specific Gata3 Ablation Identifies the Maturation Program Required for Bone Marrow Exit and Control of Proliferation.
J Immunol. 196(4):1753-67Linear ubiquitination by LUBEL has a role in Drosophila heat stress response.
EMBO Rep. 17(11):1624-1640The CDK9 Inhibitor Dinaciclib Exerts Potent Apoptotic and Antitumor Effects in Preclinical Models of MLL-Rearranged Acute Myeloid Leukemia.
Cancer Res. 76(5):1158-69An Inducible Retroviral Expression System for Tandem Affinity Purification Mass-Spectrometry-Based Proteomics Identifies Mixed Lineage Kinase Domain-like Protein (MLKL) as an Heat Shock Protein 90 (HSP90) Client.
Mol Cell Proteomics. 15(3):1139-50Mutations in the murine homologue of TUBB5 cause microcephaly by perturbing cell cycle progression and inducing p53-associated apoptosis.
Development. 143(7):1126-33Mutations in the HECT domain of NEDD4L lead to AKT-mTOR pathway deregulation and cause periventricular nodular heterotopia.
Nat Genet. 48(11):1349-1358Dual RING E3 Architectures Regulate Multiubiquitination and Ubiquitin Chain Elongation by APC/C.
Cell. 165(6):1440-1453Decoding sORF translation - from small proteins to gene regulation.
RNA Biol. 13(11):1051-1059MuSK Kinase Activity is Modulated By A Serine Phosphorylation Site in The Kinase Loop.
Sci Rep. 6:33583Rapid movement and transcriptional re-localization of human cohesin on DNA.
EMBO J. 35(24):2671-2685The Helix-Loop-Helix Protein ID2 Governs NK Cell Fate by Tuning Their Sensitivity to Interleukin-15.
Immunity. 44(1):103-115Structural and Functional Characterization of the Bacterial Type III Secretion Export Apparatus.
PLoS Pathog. 12(12):e1006071Neuron type-specific miRNA represses two broadly expressed genes to modulate an avoidance behavior in C. elegans.
Genes Dev. 30(18):2042-2047Structural mechanism for the recognition and ubiquitination of a single nucleosome residue by Rad6-Bre1.
Proc Natl Acad Sci U S A. 113(38):10553-8Id2 and E Proteins Orchestrate the Initiation and Maintenance of MLL-Rearranged Acute Myeloid Leukemia.
Cancer Cell. 30(1):59-74De Novo Mutations in DENR Disrupt Neuronal Development and Link Congenital Neurological Disorders to Faulty mRNA Translation Re-initiation.
Cell Rep. 15(10):2251-2265Deletions and de novo mutations of SOX11 are associated with a neurodevelopmental disorder with features of Coffin-Siris syndrome.
J Med Genet. 53(3):152-62Structural basis for the disaggregase activity and regulation of Hsp104.
Elife. 5Topology and structure of an engineered human cohesin complex bound to Pds5B.
Nat Commun. 7:12523β-catenin activity in late hypertrophic chondrocytes locally orchestrates osteoblastogenesis and osteoclastogenesis.
Development. 143(20):3826-3838Molecular basis of outer kinetochore assembly on CENP-T.
Elife. 5Regulation of two motor patterns enables the gradual adjustment of locomotion strategy in Caenorhabditis elegans.
Elife. 5ARHGEF17 is an essential spindle assembly checkpoint factor that targets Mps1 to kinetochores.
J Cell Biol. 212(6):647-59Measuring APC/C-Dependent Ubiquitylation In Vitro.
Methods Mol Biol. 1342:287-303SIRT2 regulates nuclear envelope reassembly through ANKLE2 deacetylation.
J Cell Sci. 129(24):4607-4621Polysialylation controls dendritic cell trafficking by regulating chemokine recognition.
Science. 351(6269):186-90Intact Cohesion, Anaphase, and Chromosome Segregation in Human Cells Harboring Tumor-Derived Mutations in STAG2.
PLoS Genet. 12(2):e1005865A Kinase-Independent Function of CDK6 Links the Cell Cycle to Tumor Angiogenesis.
Cancer Cell. 30(2):359-360Sororin actively maintains sister chromatid cohesion.
EMBO J. 35(6):635-53A de novo frameshift in HNRNPK causing a Kabuki-like syndrome with nodular heterotopia.
Clin Genet. 90(3):258-62CXCR5(+) follicular cytotoxic T cells control viral infection in B cell follicles.
Nat Immunol. 17(10):1187-96Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes.
Science. 352(6284):459-63Exploring the role of sphingolipid machinery during the epithelial to mesenchymal transition program using an integrative approach.
Oncotarget. 7(16):22295-323Multifunctional role of the transcription factor Blimp-1 in coordinating plasma cell differentiation.
Nat Immunol. 17(3):331-43The tumor microenvironment and Immunoscore are critical determinants of dissemination to distant metastasis.
Sci Transl Med. 8(327):327ra26A Force-Induced Directional Switch of a Molecular Motor Enables Parallel Microtubule Bundle Formation.
Cell. 167(2):539-552.e14Oxygen-induced social behaviours in Pristionchus pacificus have a distinct evolutionary history and genetic regulation from Caenorhabditis elegans.
Proc Biol Sci. 283(1825):20152263Gene Regulation: Activation through Space.
Curr Biol. 26(19):R895-R898MEK1 is required for the development of NRAS-driven leukemia.
Oncotarget. 7(49):80113-80130Activation of an exonic splice-donor site in exon 30 of CDK5RAP2 in a patient with severe microcephaly and pigmentary abnormalities.
Clin Case Rep. 4(10):952-956PU.1 cooperates with IRF4 and IRF8 to suppress pre-B-cell leukemia.
Leukemia. 30(6):1375-87Automatic Segmentation of Drosophila Neural Compartments Using GAL4 Expression Data Reveals Novel Visual Pathways.
Curr Biol. 26(15):1943-1954Retrotransposon derepression leads to activation of the unfolded protein response and apoptosis in pro-B cells.
Development. 143(10):1788-99CCAN Assembly Configures Composite Binding Interfaces to Promote Cross-Linking of Ndc80 Complexes at the Kinetochore.
Curr Biol. 26(17):2370-8Dbl2 Regulates Rad51 and DNA Joint Molecule Metabolism to Ensure Proper Meiotic Chromosome Segregation.
PLoS Genet. 12(6):e1006102Fast volumetric calcium imaging across multiple cortical layers using sculpted light.
Nat Methods. 13(12):1021-1028Mechanism of APC/CCDC20 activation by mitotic phosphorylation.
Proc Natl Acad Sci U S A. 113(19):E2570-8Correction to "Comprehensive Cross-Linking Mass Spectrometry Reveals Parallel Orientation and Flexible Conformations of Plant HOP2-MND1".
J Proteome Res. 15(5):1732Editorial overview: Cell reprogramming, regeneration and repair.
Curr Opin Genet Dev. 40:iv-viMolecular basis for cytoplasmic RNA surveillance by uridylation-triggered decay in Drosophila.
EMBO J. 35(22):2417-2434An Evolutionary Conserved Epigenetic Mark of Polycomb Response Elements Implemented by Trx/MLL/COMPASS.
Mol Cell. 63(2):318-328Mapping the chemical chromatin reactivation landscape identifies BRD4-TAF1 cross-talk.
Nat Chem Biol. 12(7):504-10Genome-Wide Ultrabithorax Binding Analysis Reveals Highly Targeted Genomic Loci at Developmental Regulators and a Potential Connection to Polycomb-Mediated Regulation.
PLoS One. 11(8):e0161997RANKL/RANK control Brca1 mutation- .
Cell Res. 26(7):761-74The BTB domains of the potassium channel tetramerization domain proteins prevalently assume pentameric states.
FEBS Lett. 590(11):1663-71RNA-binding profiles of Drosophila CPEB proteins Orb and Orb2.
Proc Natl Acad Sci U S A. 113(45):E7030-E7038Chemical Biology Interrogates Protein Arginine Phosphorylation.
Cell Chem Biol. 23(8):888-90Blimp-1 controls plasma cell function through the regulation of immunoglobulin secretion and the unfolded protein response.
Nat Immunol. 17(3):323-30Direct detection of a single photon by humans.
Nat Commun. 7:12172SWI/SNF regulates a transcriptional program that induces senescence to prevent liver cancer.
Genes Dev. 30(19):2187-2198Adaptive and Background-Aware GAL4 Expression Enhancement of Co-registered Confocal Microscopy Images.
Neuroinformatics. 14(2):221-33Arginine phosphorylation marks proteins for degradation by a Clp protease.
Nature. 539(7627):48-53Paul Ehrlich (1854-1915) and His Contributions to the Foundation and Birth of Translational Medicine.
J Innate Immun. 8(2):111-20biGBac enables rapid gene assembly for the expression of large multisubunit protein complexes.
Proc Natl Acad Sci U S A. 113(19):E2564-9DNA Replication Origins in Immunoglobulin Switch Regions Regulate Class Switch Recombination in an R-Loop-Dependent Manner.
Cell Rep. 17(11):2927-2942A Combination of CRISPR/Cas9 and Standardized RNAi as a Versatile Platform for the Characterization of Gene Function.
G3 (Bethesda). 6(8):2467-78C. elegans Body Cavity Neurons Are Homeostatic Sensors that Integrate Fluctuations in Oxygen Availability and Internal Nutrient Reserves.
Cell Rep. 14(7):1641-1654Molecular functions of the transcription factors E2A and E2-2 in controlling germinal center B cell and plasma cell development.
J Exp Med. 213(7):1201-21Cryo-EM of Mitotic Checkpoint Complex-Bound APC/C Reveals Reciprocal and Conformational Regulation of Ubiquitin Ligation.
Mol Cell. 63(4):593-607Regulatory Enhancer-Core-Promoter Communication via Transcription Factors and Cofactors.
Trends Genet. 32(12):801-814Anion-exchange chromatography of phosphopeptides: weak anion exchange versus strong anion exchange and anion-exchange chromatography versus electrostatic repulsion-hydrophilic interaction chromatography.
Anal Chem. 87(9):4704-11An inducible retroviral expression system for tandem affinity purification mass-spectrometry-based proteomics identifies MLKL as an HSP90 client.
Mol Cell Proteomics.The Expression of Tubb2b Undergoes a Developmental Transition in Murine Cortical Neurons.
J Comp Neurol. 523(15):2161-86Direct and indirect targeting of MYC to treat acute myeloid leukemia.
Cancer Chemother Pharmacol. 76(1):35-46RING E3 mechanism for ubiquitin ligation to a disordered substrate visualized for human anaphase-promoting complex.
Proc Natl Acad Sci U S A. 112(17):5272-9ProteoPlex: stability optimization of macromolecular complexes by sparse-matrix screening of chemical space.
Nat Methods. 12(9):859-65The histone chaperone CAF-1 safeguards somatic cell identity.
Nature. 528(7581):218-24Conserved piRNA Expression from a Distinct Set of piRNA Cluster Loci in Eutherian Mammals.
PLoS Genet. 11(11):e1005652Atomic-accuracy models from 4.5-Å cryo-electron microscopy data with density-guided iterative local refinement.
Nat Methods. 12(4):361-365Spatial Regulation of V-(D)J Recombination at Antigen Receptor Loci.
Adv Immunol. 128:93-121No evidence for intracellular magnetite in putative vertebrate magnetoreceptors identified by magnetic screening.
Proc Natl Acad Sci U S A. 112(1):262-7Caffeine-induced diuresis and natriuresis is independent of renal tubular NHE3.
Am J Physiol Renal Physiol. 308(12):F1409-20Disruption of STAT3 signalling promotes KRAS-induced lung tumorigenesis.
Nat Commun. 6:6285Erratum: Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia.
Nat Chem Biol. 11(10):815G0/G1 Switch Gene 2 Regulates Cardiac Lipolysis.
J Biol Chem. 290(43):26141-50Rio1 promotes rDNA stability and downregulates RNA polymerase I to ensure rDNA segregation.
Nat Commun. 6:6643Mutations in PIGY: expanding the phenotype of inherited glycosylphosphatidylinositol deficiencies.
Hum Mol Genet. 24(21):6146-59Mutations in Either TUBB or MAPRE2 Cause Circumferential Skin Creases Kunze Type.
Am J Hum Genet. 97(6):790-800Global brain dynamics embed the motor command sequence of Caenorhabditis elegans.
Cell. 163(3):656-69Transgenesis in axolotl (Ambystoma mexicanum).
Methods Mol Biol. 1290:269-77Synaptic Orb2A Bridges Memory Acquisition and Late Memory Consolidation in Drosophila.
Cell Rep. 11(12):1953-65Imprinted expression in cystic embryoid bodies shows an embryonic and not an extra-embryonic pattern.
Dev Biol. 402(2):291-305Arabidopsis PCH2 Mediates Meiotic Chromosome Remodeling and Maturation of Crossovers.
PLoS Genet. 11(7):e1005372Predicting the Dynamics of Network Connectivity in the Neocortex.
J Neurosci. 35(36):12535-44Functional-genetic dissection of HDAC dependencies in mouse lymphoid and myeloid malignancies.
Blood. 126(21):2392-403Non-catalytic motor domains enable processive movement and functional diversification of the kinesin-14 Kar3.
Elife. 4STARR-seq - principles and applications.
Genomics. 106(3):145-150Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt.
Genes Dev. 29(5):501-12The evolutionarily conserved transcription factor PRDM12 controls sensory neuron development and pain perception.
Cell Cycle. 14(12):1799-8083DSpectra: A 3-dimensional quantification algorithm for LC-MS labeled profile data.
J Proteomics. 112:156-65Pillars Article: Commitment to the B-lymphoid lineage depends on the transcription factor Pax5. Nature. 1999. 401: 556-562.
J Immunol. 195(3):766-72MUCOSAL IMMUNOLOGY. The microbiota regulates type 2 immunity through RORγt⁺ T cells.
Science. 349(6251):989-93Germline recessive mutations in PI4KA are associated with perisylvian polymicrogyria, cerebellar hypoplasia and arthrogryposis.
Hum Mol Genet. 24(13):3732-41Antisense Oligonucleotide-Mediated Transcript Knockdown in Zebrafish.
PLoS One. 10(10):e0139504Casein Kinase 1 and Phosphorylation of Cohesin Subunit Rec11 (SA3) Promote Meiotic Recombination through Linear Element Formation.
PLoS Genet. 11(5):e1005225Determinants of amyloid fibril degradation by the PDZ protease HTRA1.
Nat Chem Biol. 11(11):862-9Comprehensive Cross-Linking Mass Spectrometry Reveals Parallel Orientation and Flexible Conformations of Plant HOP2-MND1.
J Proteome Res. 14(12):5048-62Transcriptional plasticity promotes primary and acquired resistance to BET inhibition.
Nature. 525(7570):543-547High-efficiency electroporation of the spinal cord in larval axolotl.
Methods Mol Biol. 1290:115-25Planar cell polarity-mediated induction of neural stem cell expansion during axolotl spinal cord regeneration.
Elife. 4:e10230Quantitative phosphoproteomics of the ataxia telangiectasia-mutated (ATM) and ataxia telangiectasia-mutated and rad3-related (ATR) dependent DNA damage response in Arabidopsis thaliana.
Mol Cell Proteomics. 14(3):556-71Efficacy and mechanism of action of volasertib, a potent and selective inhibitor of Polo-like kinases, in preclinical models of acute myeloid leukemia.
J Pharmacol Exp Ther. 352(3):579-89Optimizing and extending light-sculpting microscopy for fast functional imaging in neuroscience.
Biomed Opt Express. 6(2):353-68Combining the differentiating effect of panobinostat with the apoptotic effect of arsenic trioxide leads to significant survival benefit in a model of t(8;21) acute myeloid leukemia.
Clin Epigenetics. 7:2CDK6 as a key regulator of hematopoietic and leukemic stem cell activation.
Blood. 125(1):90-101The Nuclear Pore-Associated TREX-2 Complex Employs Mediator to Regulate Gene Expression.
Cell. 162(5):1016-28Hyperactivation of mTORC1 and mTORC2 by multiple oncogenic events causes addiction to eIF4E-dependent mRNA translation in T-cell leukemia.
Oncogene. 34(27):3593-604Burst muscle performance predicts the speed, acceleration, and turning performance of Anna's hummingbirds.
Elife. 4:e11159Laser-induced acoustic desorption of natural and functionalized biochromophores.
Anal Chem. 87(11):5614-9The RNA-binding protein Arrest (Bruno) regulates alternative splicing to enable myofibril maturation in Drosophila flight muscle.
EMBO Rep. 16(2):178-91Transcriptional regulators form diverse groups with context-dependent regulatory functions.
Nature. 528(7580):147-51Visualizing KcsA conformational changes upon ion binding by infrared spectroscopy and atomistic modeling.
J Phys Chem B. 119(18):5824-31Identification of bromodomain-containing protein-4 as a novel marker and epigenetic target in mast cell leukemia.
Leukemia. 29(11):2230-7Activated Notch counteracts Ikaros tumor suppression in mouse and human T-cell acute lymphoblastic leukemia.
Leukemia. 29(6):1301-11Structure of an APC3-APC16 complex: insights into assembly of the anaphase-promoting complex/cyclosome.
J Mol Biol. 427(8):1748-64Thymic B Cells Are Licensed to Present Self Antigens for Central T Cell Tolerance Induction.
Immunity. 42(6):1048-61The Deubiquitinase USP37 Regulates Chromosome Cohesion and Mitotic Progression.
Curr Biol. 25(17):2290-9Enhancer-core-promoter specificity separates developmental and housekeeping gene regulation.
Nature. 518(7540):556-9Cooperative loss of RAS feedback regulation drives myeloid leukemogenesis.
Nat Genet. 47(5):539-43Quantitative genome-wide enhancer activity maps for five Drosophila species show functional enhancer conservation and turnover during cis-regulatory evolution.
Nat Genet. 46(7):685-92Measuring the functional organization of the neocortex at large and small scales.
Neuron. 83(4):756-8FlyMAD: rapid thermogenetic control of neuronal activity in freely walking Drosophila.
Nat Methods. 11(7):756-62Neuronal control of Drosophila walking direction.
Science. 344(6179):97-101Differentiation therapy for the treatment of t(8;21) acute myeloid leukemia using histone deacetylase inhibitors.
Blood. 123(9):1341-52Microtubules and neurodevelopmental disease: the movers and the makers.
Adv Exp Med Biol. 800:75-96Mechanism of polyubiquitination by human anaphase-promoting complex: RING repurposing for ubiquitin chain assembly.
Mol Cell. 56(2):246-260Preclinical efficacy of MEK inhibition in Nras-mutant AML.
Blood. 124(26):3947-55Epigenetic control of immunity.
Cold Spring Harb Perspect Biol. 6(6)Central amygdala PKC-δ(+) neurons mediate the influence of multiple anorexigenic signals.
Nat Neurosci. 17(9):1240-8Characterization of a mouse model with complete RPE loss and its use for RPE cell transplantation.
Invest Ophthalmol Vis Sci. 55(8):5431-44Mathematical modeling of regenerative processes.
Curr Top Dev Biol. 108:283-317MLL3 is a haploinsufficient 7q tumor suppressor in acute myeloid leukemia.
Cancer Cell. 25(5):652-65Diversity and wiring variability of visual local neurons in the Drosophila medulla M6 stratum.
J Comp Neurol. 522(17):3795-816Two distinct types of neuronal asymmetries are controlled by the Caenorhabditis elegans zinc finger transcription factor die-1.
Genes Dev. 28(1):34-43Automated image-based tracking and its application in ecology.
Trends Ecol Evol. 29(7):417-28ZRF1 controls the retinoic acid pathway and regulates leukemogenic potential in acute myeloid leukemia.
Oncogene. 33(48):5501-10RNA specificity and regulation of catalysis in the eukaryotic polynucleotide kinase Clp1.
Mol Cell. 54(6):975-86Is salamander hindlimb regeneration similar to that of the forelimb? Anatomical and morphogenetic analysis of hindlimb muscle regeneration in GFP-transgenic axolotls as a basis for regenerative and developmental studies.
J Anat. 224(4):459-68Is salamander limb regeneration really perfect? Anatomical and morphogenetic analysis of forelimb muscle regeneration in GFP-transgenic axolotls as a basis for regenerative, developmental, and evolutionary studies.
Anat Rec (Hoboken). 297(6):1076-89Development of fore- and hindlimb muscles in GFP-transgenic axolotls: morphogenesis, the tetrapod bauplan, and new insights on the forelimb-hindlimb enigma.
J Exp Zool B Mol Dev Evol. 322(2):106-27MS Amanda, a universal identification algorithm optimized for high accuracy tandem mass spectra.
J Proteome Res. 13(8):3679-84Global analysis of muscle-specific kinase signaling by quantitative phosphoproteomics.
Mol Cell Proteomics. 13(8):1993-2003CRISPR-mediated genomic deletion of Sox2 in the axolotl shows a requirement in spinal cord neural stem cell amplification during tail regeneration.
Stem Cell Reports. 3(3):444-59Ascending SAG neurons control sexual receptivity of Drosophila females.
Neuron. 83(1):135-48Asymmetric processing of visual motion for simultaneous object and background responses.
Curr Biol. 24(24):2913-9Flying Drosophila stabilize their vision-based velocity controller by sensing wind with their antennae.
Proc Natl Acad Sci U S A. 111(13):E1182-91Bacterial type III secretion systems: specialized nanomachines for protein delivery into target cells.
Annu Rev Microbiol. 68:415-38Regulation of gene expression through a transcriptional repressor that senses acyl-chain length in membrane phospholipids.
Dev Cell. 29(6):729-39A cooperative mechanism drives budding yeast kinetochore assembly downstream of CENP-A.
J Cell Biol. 206(4):509-24Mutations in PGAP3 impair GPI-anchor maturation, causing a subtype of hyperphosphatasia with mental retardation.
Am J Hum Genet. 94(2):278-87CDK9-mediated transcription elongation is required for MYC addiction in hepatocellular carcinoma.
Genes Dev. 28(16):1800-14Characterization of a DNA exit gate in the human cohesin ring.
Science. 346(6212):968-72The mammalian tRNA ligase complex mediates splicing of XBP1 mRNA and controls antibody secretion in plasma cells.
EMBO J. 33(24):2922-36Human CLP1 mutations alter tRNA biogenesis, affecting both peripheral and central nervous system function.
Cell. 157(3):636-50Optimized axolotl (Ambystoma mexicanum) husbandry, breeding, metamorphosis, transgenesis and tamoxifen-mediated recombination.
Nat Protoc. 9(3):529-40Germline Transgenic Methods for Tracking Cells and Testing Gene Function during Regeneration in the Axolotl.
Stem Cell Reports. 2(2):243Differentiation of type 1 ILCs from a common progenitor to all helper-like innate lymphoid cell lineages.
Cell. 157(2):340-356Development and performance evaluation of an ultralow flow nanoliquid chromatography-tandem mass spectrometry set-up.
Proteomics. 14(17-18):1999-2007Genome-scale functional characterization of Drosophila developmental enhancers in vivo.
Nature. 512(7512):91-5Cohesin's ATPase activity couples cohesin loading onto DNA with Smc3 acetylation.
Curr Biol. 24(19):2228-37Pax5 loss imposes a reversible differentiation block in B-progenitor acute lymphoblastic leukemia.
Genes Dev. 28(12):1337-50"Uno, nessuno e centomila": the different faces of the budding yeast kinetochore.
Chromosoma. 123(5):447-57Neural circuit components of the Drosophila OFF motion vision pathway.
Curr Biol. 24(4):385-923D reconstitution of the patterned neural tube from embryonic stem cells.
Stem Cell Reports. 3(6):987-99cis-regulatory requirements for tissue-specific programs of the circadian clock.
Curr Biol. 24(1):1-10The AAA-ATPase molecular chaperone Cdc48/p97 disassembles sumoylated centromeres, decondenses heterochromatin, and activates ribosomal RNA genes.
Proc Natl Acad Sci U S A. 111(45):16166-71Alternative 3' UTR selection controls PAR-5 homeostasis and cell polarity in C. elegans embryos.
Cell Rep. 8(5):1380-90Deep and precise quantification of the mouse synaptosomal proteome reveals substantial remodeling during postnatal maturation.
J Proteome Res. 13(10):4310-24Electron tomography and simulation of baculovirus actin comet tails support a tethered filament model of pathogen propulsion.
PLoS Biol. 12(1):e1001765TUBB5 and its disease-associated mutations influence the terminal differentiation and dendritic spine densities of cerebral cortical neurons.
Hum Mol Genet. 23(19):5147-58Versatile in vitro system to study translocation and functional integration of bacterial outer membrane proteins.
Nat Commun. 5:5396Analysis of orthologous groups reveals archease and DDX1 as tRNA splicing factors.
Nature. 511(7507):104-7Simultaneous whole-animal 3D imaging of neuronal activity using light-field microscopy.
Nat Methods. 11(7):727-730B cell super-enhancers and regulatory clusters recruit AID tumorigenic activity.
Cell. 159(7):1524-37Structure of a pathogenic type 3 secretion system in action.
Nat Struct Mol Biol. 21(1):82-7A dual role for autophagy in a murine model of lung cancer.
Nat Commun. 5:3056A conserved role for Snail as a potentiator of active transcription.
Genes Dev. 28(2):167-81NDST1 missense mutations in autosomal recessive intellectual disability.
Am J Med Genet A. 164A(11):2753-63In vivo RNAi screening identifies a mechanism of sorafenib resistance in liver cancer.
Nat Med. 20(10):1138-46Fundamental differences in dedifferentiation and stem cell recruitment during skeletal muscle regeneration in two salamander species.
Cell Stem Cell. 14(2):174-87H3S28 phosphorylation is a hallmark of the transcriptional response to cellular stress.
Genome Res. 24(11):1808-20Quantitative phosphoproteomics reveals the role of protein arginine phosphorylation in the bacterial stress response.
Mol Cell Proteomics. 13(2):537-50Stage-specific control of early B cell development by the transcription factor Ikaros.
Nat Immunol. 15(3):283-93Differential requirement for Nfil3 during NK cell development.
J Immunol. 192(6):2667-76Transcriptional enhancers: from properties to genome-wide predictions.
Nat Rev Genet. 15(4):272-86Hormone-responsive enhancer-activity maps reveal predictive motifs, indirect repression, and targeting of closed chromatin.
Mol Cell. 54(1):180-192Msh4 and Msh5 function in SC-independent chiasma formation during the streamlined meiosis of Tetrahymena.
Genetics. 198(3):983-93Reverse Engineering Animal Vision with Virtual Reality and Genetics.
Computer. 14(190):38–45Arabidopsis PIAL1 and 2 promote SUMO chain formation as E4-type SUMO ligases and are involved in stress responses and sulfur metabolism.
Plant Cell. 26(11):4547-60Chasing Phosphoarginine Proteins: Development of a Selective Enrichment Method Using a Phosphatase Trap.
Mol Cell Proteomics. 13(8):1953-64BRD4: a BET(ter) target for the treatment of AML?
Cell Cycle. 13(5):689-90SNW1 enables sister chromatid cohesion by mediating the splicing of sororin and APC2 pre-mRNAs.
EMBO J. 33(22):2643-58Cellular and behavioral functions of fruitless isoforms in Drosophila courtship.
Curr Biol. 24(3):242-51A DEK domain-containing protein modulates chromatin structure and function in Arabidopsis.
Plant Cell. 26(11):4328-44qcML: an exchange format for quality control metrics from mass spectrometry experiments.
Mol Cell Proteomics. 13(8):1905-13Epigenetic targeting of activation-induced cytidine deaminase.
Proc Natl Acad Sci U S A. 111(52):18667-72Regulation of NO synthesis, local inflammation, and innate immunity to pathogens by BET family proteins.
Mol Cell Biol. 34(3):415-27Jagunal homolog 1 is a critical regulator of neutrophil function in fungal host defense.
Nat Genet. 46(9):1028-33Dissection of thousands of cell type-specific enhancers identifies dinucleotide repeat motifs as general enhancer features.
Genome Res. 24(7):1147-56Cellular and molecular basis of decision-making.
EMBO Rep. 15(10):1023-35Development of siRNA payloads to target KRAS-mutant cancer.
Cancer Discov. 4(10):1182-1197Downregulation of RUNX1/CBFβ by MLL fusion proteins enhances hematopoietic stem cell self-renewal.
Blood. 123(11):1729-38Genome-wide quantitative enhancer activity maps identified by STARR-seq.
Science. 339(6123):1074-7Analysis of transduction efficiency, tropism and axonal transport of AAV serotypes 1, 2, 5, 6, 8 and 9 in the mouse brain.
PLoS One. 8(9):e76310Identification of transcription factor binding sites from ChIP-seq data at high resolution.
Bioinformatics. 29(21):2705-13A multiplicative reinforcement learning model capturing learning dynamics and interindividual variability in mice.
Proc Natl Acad Sci U S A. 110(49):19950-5Multiple mechanisms contribute to centriole separation in C. elegans.
Curr Biol. 23(14):1380-7Discriminating external and internal causes for heading changes in freely flying Drosophila.
PLoS Comput Biol. 9(2):e1002891Periventricular heterotopia in 6q terminal deletion syndrome: role of the C6orf70 gene.
Brain. 136(Pt 11):3378-94Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant.
Chromosome Res. 21(2):101-6Control of antigen receptor diversity through spatial regulation of V(D)J recombination.
Cold Spring Harb Symp Quant Biol. 78:11-21Spectrally coded optical nanosectioning (SpecON) with biocompatible metal-dielectric-coated substrates.
Proc Natl Acad Sci U S A. 110(50):20069-74Erythropoiesis and globin switching in compound Klf1::Bcl11a mutant mice.
Blood. 121(13):2553-62An optimized microRNA backbone for effective single-copy RNAi.
Cell Rep. 5(6):1704-13Co-expression of VAL- and TMT-opsins uncovers ancient photosensory interneurons and motorneurons in the vertebrate brain.
PLoS Biol. 11(6):e1001585GATA-3 regulates the self-renewal of long-term hematopoietic stem cells.
Nat Immunol. 14(10):1037-44Unambiguous phosphosite localization using electron-transfer/higher-energy collision dissociation (EThcD).
J Proteome Res. 12(3):1520-5Electron microscopy structure of human APC/C(CDH1)-EMI1 reveals multimodal mechanism of E3 ligase shutdown.
Nat Struct Mol Biol. 20(7):827-35Structural basis for recognizing phosphoarginine and evolving residue-specific protein phosphatases in gram-positive bacteria.
Cell Rep. 3(6):1832-9The myosin chaperone UNC-45 is organized in tandem modules to support myofilament formation in C. elegans.
Cell. 152(1-2):183-95EGL-13/SoxD specifies distinct O2 and CO2 sensory neuron fates in Caenorhabditis elegans.
PLoS Genet. 9(5):e1003511CLP1 links tRNA metabolism to progressive motor-neuron loss.
Nature. 495(7442):474-80Transcription factor YY1 is essential for regulation of the Th2 cytokine locus and for Th2 cell differentiation.
Proc Natl Acad Sci U S A. 110(1):276-81Interlaboratory studies and initiatives developing standards for proteomics.
Proteomics. 13(6):904-9Spatial distribution of prominin-1 (CD133)-positive cells within germinative zones of the vertebrate brain.
PLoS One. 8(5):e63457Transcriptome and proteome quantification of a tumor model provides novel insights into post-transcriptional gene regulation.
Genome Biol. 14(11):r133Drosophila Embryo Stage Annotation using Label Propagation
International Conference on Computer Vision (ICCV). Springer. Dec:1089–1096Foamy virus for efficient gene transfer in regeneration studies.
BMC Dev Biol. 13:17Comparative transcriptional profiling of the axolotl limb identifies a tripartite regeneration-specific gene program.
PLoS One. 8(5):e61352A kinase-independent function of CDK6 links the cell cycle to tumor angiogenesis.
Cancer Cell. 24(2):167-81Muscle and connective tissue progenitor populations show distinct Twist1 and Twist3 expression profiles during axolotl limb regeneration.
Dev Biol. 373(1):196-204Molecular requirements for the formation of a kinetochore-microtubule interface by Dam1 and Ndc80 complexes.
J Cell Biol. 200(1):21-30An iron-rich organelle in the cuticular plate of avian hair cells.
Curr Biol. 23(10):924-9A comprehensive wiring diagram of the protocerebral bridge for visual information processing in the Drosophila brain.
Cell Rep. 3(5):1739-53Parallel neural pathways mediate CO2 avoidance responses in Drosophila.
Science. 340(6138):1338-41Intron excision from precursor tRNA molecules in mammalian cells requires ATP hydrolysis and phosphorylation of tRNA-splicing endonuclease components.
Biochem Soc Trans. 41(4):831-7A directional tuning map of Drosophila elementary motion detectors.
Nature. 500(7461):212-6A structural basis for kinetochore recruitment of the Ndc80 complex via two distinct centromere receptors.
EMBO J. 32(3):409-23Id2-mediated inhibition of E2A represses memory CD8+ T cell differentiation.
J Immunol. 190(9):4585-94CtpB assembles a gated protease tunnel regulating cell-cell signaling during spore formation in Bacillus subtilis.
Cell. 155(3):647-58Flexible long-range loops in the VH gene region of the Igh locus facilitate the generation of a diverse antibody repertoire.
Immunity. 39(2):229-44Dynamics of dendritic spines in the mouse auditory cortex during memory formation and memory recall.
Proc Natl Acad Sci U S A. 110(45):18315-20Optimized nonlinear gradients for reversed-phase liquid chromatography in shotgun proteomics.
Anal Chem. 85(16):7777-85Connective tissue cells, but not muscle cells, are involved in establishing the proximo-distal outcome of limb regeneration in the axolotl.
Development. 140(3):513-8Aurora B and Cdk1 mediate Wapl activation and release of acetylated cohesin from chromosomes by phosphorylating Sororin.
Proc Natl Acad Sci U S A. 110(33):13404-9GABAergic neurons regulate lateral ventricular development via transcription factor Pax5.
Genesis. 51(4):234-45Analysis of meiotic protein complexes from Arabidopsis and Brassica using affinity-based proteomics.
Methods Mol Biol. 990:215-26Transgenic mouse models enabling photolabeling of individual neurons in vivo.
PLoS One. 8(4):e62132Yeast protein phosphatase 2A-Cdc55 regulates the transcriptional response to hyperosmolarity stress by regulating Msn2 and Msn4 chromatin recruitment.
Mol Cell Biol. 33(5):1057-72Progressive specification rather than intercalation of segments during limb regeneration.
Science. 342(6164):1375-9Studying the fragmentation behavior of peptides with arginine phosphorylation and its influence on phospho-site localization.
Proteomics. 13(6):945-54Brain-wide 3D imaging of neuronal activity in Caenorhabditis elegans with sculpted light.
Nat Methods. 10(10):1013-20The Polycomb complex PRC2 supports aberrant self-renewal in a mouse model of MLL-AF9;Nras(G12D) acute myeloid leukemia.
Oncogene. 32(7):930-8Role of SWI/SNF in acute leukemia maintenance and enhancer-mediated Myc regulation.
Genes Dev. 27(24):2648-62Protein-mediated transformation of lipid vesicles into tubular networks.
Biophys J. 105(3):711-9Life(span) in balance: oxygen fuels a sophisticated neural network for lifespan homeostasis in C. elegans.
EMBO J. 32(11):1499-501Regulatory Genomics - Decoding Drosophila Regulatory Sequences.
Biomed Tech (Berl). 58 Suppl 1Comparative RNA-seq analysis in the unsequenced axolotl: the oncogene burst highlights early gene expression in the blastema.
PLoS Comput Biol. 9(3):e1002936Wapl is an essential regulator of chromatin structure and chromosome segregation.
Nature. 501(7468):564-8High resolution anatomical mapping confirms the absence of a magnetic sense system in the rostral upper beak of pigeons.
Commun Integr Biol. 6(4):e24859Mutation of the diamond-blackfan anemia gene Rps7 in mouse results in morphological and neuroanatomical phenotypes.
PLoS Genet. 9(1):e1003094Family matters: structural and functional conservation of centromere-associated proteins from yeast to humans.
Trends Cell Biol. 23(6):260-9Deciphering the transcriptional cis-regulatory code.
Trends Genet. 29(1):11-22Circadian and circalunar clock interactions in a marine annelid.
Cell Rep. 5(1):99-113Three-dimensional neuroepithelial culture from human embryonic stem cells and its use for quantitative conversion to retinal pigment epithelium.
PLoS One. 8(1):e54552Discrete neocortical dynamics predict behavioral categorization of sounds.
Neuron. 76(2):435-49FACS purification and transcriptome analysis of drosophila neural stem cells reveals a role for Klumpfuss in self-renewal.
Cell Rep. 2(2):407-18An insertional mutagenesis screen identifies genes that cooperate with Mll-AF9 in a murine leukemogenesis model.
Blood. 119(19):4512-23Centrosomes can initiate a polarity axis from any position within one-cell C. elegans embryos.
Curr Biol. 22(7):583-9Methods in cell biology: analysis of cell polarity in C. elegans embryos.
Methods Cell Biol. 107:207-38Mutations in the β-tubulin gene TUBB5 cause microcephaly with structural brain abnormalities.
Cell Rep. 2(6):1554-62The Arabidopsis HEI10 is a new ZMM protein related to Zip3.
PLoS Genet. 8(7):e1002799Stress-induced GSK3 regulates the redox stress response by phosphorylating glucose-6-phosphate dehydrogenase in Arabidopsis.
Plant Cell. 24(8):3380-92Regulation of DNA replication within the immunoglobulin heavy-chain locus during B cell commitment.
PLoS Biol. 10(7):e1001360Anatomy of the pectoral and forelimb muscles of wildtype and green fluorescent protein-transgenic axolotls and comparison with other tetrapods including humans: a basis for regenerative, evolutionary and developmental studies.
J Anat. 221(6):622-35A pipeline for the generation of shRNA transgenic mice.
Nat Protoc. 7(2):374-93Neural crest does not contribute to the neck and shoulder in the axolotl (Ambystoma mexicanum).
PLoS One. 7(12):e52244Inter-homolog crossing-over and synapsis in Arabidopsis meiosis are dependent on the chromosome axis protein AtASY3.
PLoS Genet. 8(2):e1002507Induced heterodimerization and purification of two target proteins by a synthetic coiled-coil tag.
Protein Sci. 21(4):511-9Anti-apoptotic Mcl-1 is essential for the development and sustained growth of acute myeloid leukemia.
Genes Dev. 26(2):120-5Small-molecule inhibition of BRD4 as a new potent approach to eliminate leukemic stem- and progenitor cells in acute myeloid leukemia AML.
Oncotarget. 3(12):1588-99A histone deacetylase adjusts transcription kinetics at coding sequences during Candida albicans morphogenesis.
PLoS Genet. 8(12):e1003118The transcription factor GATA-3 controls cell fate and maintenance of type 2 innate lymphoid cells.
Immunity. 37(4):634-48Combinatorial activation and repression by seven transcription factors specify Drosophila odorant receptor expression.
PLoS Biol. 10(3):e1001280Dopamine neurons modulate pheromone responses in Drosophila courtship learning.
Nature. 489(7414):145-9Analysis of protein mixtures from whole-cell extracts by single-run nanoLC-MS/MS using ultralong gradients.
Nat Protoc. 7(5):882-90The blueprint of the type-3 injectisome.
Philos Trans R Soc Lond B Biol Sci. 367(1592):1140-54Drosophila CPEB Orb2A mediates memory independent of Its RNA-binding domain.
Neuron. 76(2):383-95HOT regions function as patterned developmental enhancers and have a distinct cis-regulatory signature.
Genes Dev. 26(9):908-13Auditory circuit in the Drosophila brain.
Proc Natl Acad Sci U S A. 109(7):2607-12Airn transcriptional overlap, but not its lncRNA products, induces imprinted Igf2r silencing.
Science. 338(6113):1469-72Newly folded substrates inside the molecular cage of the HtrA chaperone DegQ.
Nat Struct Mol Biol. 19(2):152-7NKT cell adjuvant-based tumor vaccine for treatment of myc oncogene-driven mouse B-cell lymphoma.
Blood. 120(15):3019-29Reconstitution of the central and peripheral nervous system during salamander tail regeneration.
Proc Natl Acad Sci U S A. 109(34):E2258-66Reconstitution of the central nervous system during salamander tail regeneration from the implanted neurospheres.
Methods Mol Biol. 916:197-202Construction of a global pain systems network highlights phospholipid signaling as a regulator of heat nociception.
PLoS Genet. 8(12):e1003071Update on sumoylation: defining core components of the plant SUMO conjugation system by phylogenetic comparison.
New Phytol. 195(1):23-31Exome sequencing can detect pathogenic mosaic mutations present at low allele frequencies.
J Hum Genet. 57(1):70-2A novel nonsense CDK5RAP2 mutation in a Somali child with primary microcephaly and sensorineural hearing loss.
Am J Med Genet A. 158A(10):2577-82Induction of immediate early genes in the mouse auditory cortex after auditory cued fear conditioning to complex sounds.
Genes Brain Behav. 11(3):314-24The many functions of cohesin--different rings to rule them all?
EMBO J. 31(9):2061-3SIMPATIQCO: a server-based software suite which facilitates monitoring the time course of LC-MS performance metrics on Orbitrap instruments.
J Proteome Res. 11(11):5540-7Stem cells in the land of the rising sun: ISSCR 2012.
Cell Stem Cell. 11(5):607-14Diversity and roles of (t)RNA ligases.
Cell Mol Life Sci. 69(16):2657-70A new approach to transcription factor screening for reprogramming of fibroblasts to cardiomyocyte-like cells.
J Mol Cell Cardiol. 53(3):323-32The B-cell identity factor Pax5 regulates distinct transcriptional programmes in early and late B lymphopoiesis.
EMBO J. 31(14):3130-46CENP-T proteins are conserved centromere receptors of the Ndc80 complex.
Nat Cell Biol. 14(6):604-13Reprogramming to pluripotency is an ancient trait of vertebrate Oct4 and Pou2 proteins.
Nat Commun. 3:1279Human high temperature requirement serine protease A1 (HTRA1) degrades tau protein aggregates.
J Biol Chem. 287(25):20931-41The Drosophila female aphrodisiac pheromone activates ppk23(+) sensory neurons to elicit male courtship behavior.
Cell Rep. 1(6):599-607Clusters of iron-rich cells in the upper beak of pigeons are macrophages not magnetosensitive neurons.
Nature. 484(7394):367-70APC15 mediates CDC20 autoubiquitylation by APC/C(MCC) and disassembly of the mitotic checkpoint complex.
Nat Struct Mol Biol. 19(11):1116-23Cancer stem cell definitions and terminology: the devil is in the details.
Nat Rev Cancer. 12(11):767-75Seventy-five genetic loci influencing the human red blood cell.
Nature. 492(7429):369-75Reshaping the optical dimension in optogenetics.
Curr Opin Neurobiol. 22(1):128-37Essential role of EBF1 in the generation and function of distinct mature B cell types.
J Exp Med. 209(4):775-92Actin branching in the initiation and maintenance of lamellipodia.
J Cell Sci. 125(Pt 11):2775-85The non-redundant function of cohesin acetyltransferase Esco2: some answers and new questions.
Nucleus. 3(4):330-4Cohesin acetyltransferase Esco2 is a cell viability factor and is required for cohesion in pericentric heterochromatin.
EMBO J. 31(1):71-82A cluster of cooperating tumor-suppressor gene candidates in chromosomal deletions.
Proc Natl Acad Sci U S A. 109(21):8212-7Uncovering cis-regulatory sequence requirements for context-specific transcription factor binding.
Genome Res. 22(10):2018-30Spatiotemporal regulation of Ipl1/Aurora activity by direct Cdk1 phosphorylation.
Curr Biol. 22(9):787-93Spatial exclusivity combined with positive and negative selection of phosphorylation motifs is the basis for context-dependent mitotic signaling.
Sci Signal. 4(179):ra42Functions of Fos phosphorylation in bone homeostasis, cytokine response and tumourigenesis.
Oncogene. 30(13):1506-17A computational pipeline for comparative ChIP-seq analyses.
Nat Protoc. 7(1):45-61GMI1, a structural-maintenance-of-chromosomes-hinge domain-containing protein, is involved in somatic homologous recombination in Arabidopsis.
Plant J. 67(3):420-33General statistical modeling of data from protein relative expression isobaric tags.
J Proteome Res. 10(6):2758-66Substrate binding on the APC/C occurs between the coactivator Cdh1 and the processivity factor Doc1.
Nat Struct Mol Biol. 18(1):6-13Gene expression profile of the regeneration epithelium during axolotl limb regeneration.
Dev Dyn. 240(7):1826-40HTRA proteases: regulated proteolysis in protein quality control.
Nat Rev Mol Cell Biol. 12(3):152-62The transcription factors Blimp-1 and IRF4 jointly control the differentiation and function of effector regulatory T cells.
Nat Immunol. 12(4):304-11The distal V(H) gene cluster of the Igh locus contains distinct regulatory elements with Pax5 transcription factor-dependent activity in pro-B cells.
Immunity. 34(2):175-87Cytoarchitectural disruption of the superior colliculus and an enlarged acoustic startle response in the Tuba1a mutant mouse.
Neuroscience. 195:191-200Forward and reverse genetics through derivation of haploid mouse embryonic stem cells.
Cell Stem Cell. 9(6):563-74Using MATLAB to Achieve Nanoscale Optical Sectioning in the Vicinity of Metamaterial Substrates by Simulating Emitter-Substrate Interactions
Engineering Education and Research Using MATLAB.Functional identification of optimized RNAi triggers using a massively parallel sensor assay.
Mol Cell. 41(6):733-46Essential role of the keratinocyte-specific endonuclease DNase1L2 in the removal of nuclear DNA from hair and nails.
J Invest Dermatol. 131(6):1208-15Vibrational excitons in ionophores: experimental probes for quantum coherence-assisted ion transport and selectivity in ion channels
New J. Phys.. 13Regulation of GATA-3 expression during CD4 lineage differentiation.
J Immunol. 186(7):3892-8Targeting the SH2-kinase interface in Bcr-Abl inhibits leukemogenesis.
Cell. 147(2):306-19Quantitative phospho-proteomics to investigate the polo-like kinase 1-dependent phospho-proteome.
Mol Cell Proteomics. 10(11):M111.008540CTCF-binding elements mediate control of V(D)J recombination.
Nature. 477(7365):424-30Ectodysplasin and Wnt pathways are required for salivary gland branching morphogenesis.
Development. 138(13):2681-91Flybow: genetic multicolor cell labeling for neural circuit analysis in Drosophila melanogaster.
Nat Methods. 8(3):260-6A systematic analysis of Drosophila TUDOR domain-containing proteins identifies Vreteno and the Tdrd12 family as essential primary piRNA pathway factors.
EMBO J. 30(19):3977-93Modification of the conformational skin structure by treatment with liposomal formulations and its correlation to the penetration depth of aciclovir.
Eur J Pharm Biopharm. 79(1):76-81High conservation of transcription factor binding and evidence for combinatorial regulation across six Drosophila species.
Nat Genet. 43(5):414-20Systematic phosphorylation analysis of human mitotic protein complexes.
Sci Signal. 4(198):rs12Augmenting β-augmentation: structural basis of how BamB binds BamA and may support folding of outer membrane proteins.
J Mol Biol. 406(5):659-66Neural-specific elongation of 3' UTRs during Drosophila development.
Proc Natl Acad Sci U S A. 108(38):15864-9Lesson from the stoichiometry determination of the cohesin complex: a short protease mediated elution increases the recovery from cross-linked antibody-conjugated beads.
J Proteome Res. 10(2):780-9Molecular architecture and connectivity of the budding yeast Mtw1 kinetochore complex.
J Mol Biol. 405(2):548-59An RNA-Seq strategy to detect the complete coding and non-coding transcriptome including full-length imprinted macro ncRNAs.
PLoS One. 6(11):e27288Distinct and conserved prominin-1/CD133-positive retinal cell populations identified across species.
PLoS One. 6(3):e17590Entry of a heparan sulphate-binding HRV8 variant strictly depends on dynamin but not on clathrin, caveolin, and flotillin.
Virology. 412(1):55-67Structural adaptation of the plant protease Deg1 to repair photosystem II during light exposure.
Nat Struct Mol Biol. 18(6):728-31Altered Mascot search results by changing the m/z range of MS/MS spectra: analysis and potential applications.
Anal Bioanal Chem. 400(8):2339-47Quality control in LC-MS/MS.
Proteomics. 11(6):1026-30Ultra-high-pressure RPLC hyphenated to an LTQ-Orbitrap Velos reveals a linear relation between peak capacity and number of identified peptides.
Anal Chem. 83(7):2699-704Epigenetic regulation of learning and memory by Drosophila EHMT/G9a.
PLoS Biol. 9(1):e1000569A blueprint for kinetochores - new insights into the molecular mechanics of cell division.
Nat Rev Mol Cell Biol. 12(7):407-12A high-resolution map of human evolutionary constraint using 29 mammals.
Nature. 478(7370):476-82Multiplicative dynamics underlie the emergence of the log-normal distribution of spine sizes in the neocortex in vivo.
J Neurosci. 31(26):9481-8Differential requirement for the dual functions of β-catenin in embryonic stem cell self-renewal and germ layer formation.
Nat Cell Biol. 13(7):753-61Random mutagenesis of the prokaryotic peptide transporter YdgR identifies potential periplasmic gating residues.
J Biol Chem. 286(26):23121-31The transcription factor Pax5 regulates its target genes by recruiting chromatin-modifying proteins in committed B cells.
EMBO J. 30(12):2388-404Activation-induced cytidine deaminase (AID)-associated multigene signature to assess impact of AID in etiology of diseases with inflammatory component.
PLoS One. 6(10):e25611Pax5: a master regulator of B cell development and leukemogenesis.
Adv Immunol. 111:179-206Protein quality control in the bacterial periplasm.
Annu Rev Microbiol. 65:149-68Limb regeneration: a new development?
Annu Rev Cell Dev Biol. 27:409-40Genome-wide analysis of self-renewal in Drosophila neural stem cells by transgenic RNAi.
Cell Stem Cell. 8(5):580-93A system for imaging the regulatory noncoding Xist RNA in living mouse embryonic stem cells.
Mol Biol Cell. 22(14):2634-45Robo-3--mediated repulsive interactions guide R8 axons during Drosophila visual system development.
Proc Natl Acad Sci U S A. 108(18):7571-6Improved precision of iTRAQ and TMT quantification by an axial extraction field in an Orbitrap HCD cell.
Anal Chem. 83(4):1469-74HSPC117 is the essential subunit of a human tRNA splicing ligase complex.
Science. 331(6018):760-4Activation-induced cytidine deaminase expression in CD4+ T cells is associated with a unique IL-10-producing subset that increases with age.
PLoS One. 6(12):e29141Immersion freezing of biological specimens: rationale, principles, and instrumentation.
Cold Spring Harb Protoc. 2011(7):778-82Membrane lipidome of an epithelial cell line.
Proc Natl Acad Sci U S A. 108(5):1903-7Molecular adaptation of the DegQ protease to exert protein quality control in the bacterial cell envelope.
J Biol Chem. 286(35):30680-30690Spalt mediates an evolutionarily conserved switch to fibrillar muscle fate in insects.
Nature. 479(7373):406-9Three-dimensional model of Salmonella's needle complex at subnanometer resolution.
Science. 331(6021):1192-5EMCD real space maps of Magnetospirillum magnetotacticum.
Micron. 42(5):456-60Interstitial lung disease induced by gefitinib and toll-like receptor ligands is mediated by Fra-1.
Oncogene. 30(36):3821-32Monoglyceride lipase deficiency in mice impairs lipolysis and attenuates diet-induced insulin resistance.
J Biol Chem. 286(20):17467-77Universal and confident phosphorylation site localization using phosphoRS.
J Proteome Res. 10(12):5354-62Substrate-induced remodeling of the active site regulates human HTRA1 activity.
Nat Struct Mol Biol. 18(3):386-8Neuronal control of Drosophila courtship song.
Neuron. 69(3):509-22Confined activation and subdiffractive localization enables whole-cell PALM with genetically expressed probes.
Nat Methods. 8(4):327-33An integrated approach to dissecting oncogene addiction implicates a Myb-coordinated self-renewal program as essential for leukemia maintenance.
Genes Dev. 25(15):1628-40RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia.
Nature. 478(7370):524-8Peptide orientation affects selectivity in ion-exchange chromatography.
Anal Chem. 82(12):5253-9Vertebrates that regenerate as models for guiding stem cels.
Adv Exp Med Biol. 695:184-214Leptotene/zygotene chromosome movement via the SUN/KASH protein bridge in Caenorhabditis elegans.
PLoS Genet. 6(11):e1001219CD14 is a coreceptor of Toll-like receptors 7 and 9.
J Exp Med. 207(12):2689-701Efficient regeneration by activation of neurogenesis in homeostatically quiescent regions of the adult vertebrate brain.
Development. 137(24):4127-34Pax2 and Pax8 cooperate in mouse inner ear morphogenesis and innervation.
BMC Dev Biol. 10:89Role of the RNA/DNA kinase Grc3 in transcription termination by RNA polymerase I.
EMBO Rep. 11(10):758-64Tuba8 is expressed at low levels in the developing mouse and human brain.
Am J Hum Genet. 86(5):819-22; author reply 822-3Sexual dimorphism in the fly brain.
Curr Biol. 20(18):1589-601A novel conserved phosphotyrosine motif in the Drosophila fibroblast growth factor signaling adaptor Dof with a redundant role in signal transmission.
Mol Cell Biol. 30(8):2017-27Navigating intermediate targets: the nervous system midline.
Cold Spring Harb Perspect Biol. 2(8):a002055Mutations in the carboxyl-terminal SEC24 binding motif of the serotonin transporter impair folding of the transporter.
J Biol Chem. 285(50):39201-10Multifrequency parallelized near-field optical imaging with anistropic metal-dielectric stacks
Physical Review A. 81(5)Temperature dependence of the near-field superlensing effect for single metal layers and stacked metal-dielectric films
Proc. SPIE. 7757:77573LFast near-field imaging of spectrally broad sources using layered metallic structures
Proc. SPIE. 7757:77573MRing1B compacts chromatin structure and represses gene expression independent of histone ubiquitination.
Mol Cell. 38(3):452-64PHF8 activates transcription of rRNA genes through H3K4me3 binding and H3K9me1/2 demethylation.
Nat Struct Mol Biol. 17(4):445-50Stat5a serine 725 and 779 phosphorylation is a prerequisite for hematopoietic transformation.
Blood. 116(9):1548-58Regulation of Tbx22 during facial and palatal development.
Dev Dyn. 239(11):2860-74Wnt/β-catenin signaling in the dental mesenchyme regulates incisor development by regulating Bmp4.
Dev Biol. 348(1):97-106The structure of the Salmonella typhimurium type III secretion system needle shows divergence from the flagellar system.
J Mol Biol. 396(5):1392-7A model for cyst lumen expansion and size regulation via fluid secretion.
J Theor Biol. 264(3):1077-88Conditional deletion of histone deacetylase 1 in T cells leads to enhanced airway inflammation and increased Th2 cytokine production.
J Immunol. 185(6):3489-97Raman microspectroscopy reveals long-term extracellular activity of Chlamydiae.
Mol Microbiol. 77(3):687-700Conversion of a regulatory into a degradative protease.
J Mol Biol. 397(4):957-66PI3Kgamma protects from myocardial ischemia and reperfusion injury through a kinase-independent pathway.
PLoS One. 5(2):e9350Proteomic analysis of the outer membrane of Protochlamydia amoebophila elementary bodies.
Proteomics. 10(24):4363-76Expression and regulation of ANTXR1 in the chick embryo.
Dev Dyn. 239(2):680-7The Set3/Hos2 histone deacetylase complex attenuates cAMP/PKA signaling to regulate morphogenesis and virulence of Candida albicans.
PLoS Pathog. 6(5):e1000889Stat5 is indispensable for the maintenance of bcr/abl-positive leukaemia.
EMBO Mol Med. 2(3):98-110G9a and Glp methylate lysine 373 in the tumor suppressor p53.
J Biol Chem. 285(13):9636-9641BI 5700, a Selective Chemical Inhibitor of IκB Kinase 2, Specifically Suppresses Epithelial-Mesenchymal Transition and Metastasis in Mouse Models of Tumor Progression.
Genes Cancer. 1(2):101-14Systematic analysis of human protein complexes identifies chromosome segregation proteins.
Science. 328(5978):593-9Morphologic, functional, and occlusal characterization of mandibular lateral displacement malocclusion.
Am J Orthod Dentofacial Orthop. 137(4):454.e1-9; discussion 454-5B-lymphoid cells with attributes of dendritic cells regulate T cells via indoleamine 2,3-dioxygenase.
Proc Natl Acad Sci U S A. 107(23):10644-8Diverse endonucleolytic cleavage sites in the mammalian transcriptome depend upon microRNAs, Drosha, and additional nucleases.
Mol Cell. 38(6):781-8Rec8 phosphorylation by casein kinase 1 and Cdc7-Dbf4 kinase regulates cohesin cleavage by separase during meiosis.
Dev Cell. 18(3):397-409The role of Tuba1a in adult hippocampal neurogenesis and the formation of the dentate gyrus.
Dev Neurosci. 32(4):268-77Human rhinovirus 14 enters rhabdomyosarcoma cells expressing icam-1 by a clathrin-, caveolin-, and flotillin-independent pathway.
J Virol. 84(8):3984-92MIPs are ancestral ligands for the sex peptide receptor.
Proc Natl Acad Sci U S A. 107(14):6520-5HtrA proteases have a conserved activation mechanism that can be triggered by distinct molecular cues.
Nat Struct Mol Biol. 17(7):844-52CD271 antigen defines a subset of multipotent stromal cells with immunosuppressive and lymphohematopoietic engraftment-promoting properties.
Haematologica. 95(4):651-9The Dam1 complex confers microtubule plus end-tracking activity to the Ndc80 kinetochore complex.
J Cell Biol. 189(4):641-9Polycomb complexes act redundantly to repress genomic repeats and genes.
Genes Dev. 24(3):265-76Mechanistic concepts in X inactivation underlying dosage compensation in mammals.
Heredity (Edinb). 105(1):64-70Probing the phosphoproteome of HeLa cells using nanocast metal oxide microspheres for phosphopeptide enrichment.
Anal Chem. 82(7):2726-33MRE11 and COM1/SAE2 are required for double-strand break repair and efficient chromosome pairing during meiosis of the protist Tetrahymena.
Chromosoma. 119(5):505-18Mice lacking the orphan receptor ror1 have distinct skeletal abnormalities and are growth retarded.
Dev Dyn. 239(8):2266-77From an electrophoretic mobility shift assay to isolated transcription factors: a fast genomic-proteomic approach.
BMC Genomics. 11:644Epithelial-Mesenchymal Transition in Pancreatic Carcinoma
Cancers . 2(4):2058-2083NF-kappaB promotes epithelial-mesenchymal transition, migration and invasion of pancreatic carcinoma cells.
Cancer Lett. 295(2):214-28Opposing roles of polycomb repressive complexes in hematopoietic stem and progenitor cells.
Blood. 116(5):731-9STAT5 in B cell development and leukemia.
Curr Opin Immunol. 22(2):168-76Role of STAT5 in controlling cell survival and immunoglobulin gene recombination during pro-B cell development.
Nat Immunol. 11(2):171-9Type III secretion systems shape up as they ship out.
Curr Opin Microbiol. 13(1):47-52Tracing antigen signatures in the human IgE repertoire.
Mol Immunol. 47(14):2323-9Annexin A1 attenuates EMT and metastatic potential in breast cancer.
EMBO Mol Med. 2(10):401-14A new acid mix enhances phosphopeptide enrichment on titanium- and zirconium dioxide for mapping of phosphorylation sites on protein complexes.
J Chromatogr B Analyt Technol Biomed Life Sci. 878(5-6):515-24Characterization of a naturally-occurring p27 mutation predisposing to multiple endocrine tumors.
Mol Cancer. 9:116QIKS--Quantitative identification of kinase substrates.
Proteomics. 10(10):2015-25Reducing the haystack to find the needle: improved protein identification after fast elimination of non-interpretable peptide MS/MS spectra and noise reduction.
BMC Genomics. 11 Suppl 1:S13The Tasmanian devil transcriptome reveals Schwann cell origins of a clonally transmissible cancer.
Science. 327(5961):84-7A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene.
Cell. 143(4):628-38A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function.
Cell. 141(1):142-53Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes.
Nature. 464(7289):721-7Photounbinding of calmodulin from a family of CaM binding peptides.
PLoS One. 5(11):e14050Sororin mediates sister chromatid cohesion by antagonizing Wapl.
Cell. 143(5):737-49An in vivo RNAi assay identifies major genetic and cellular requirements for primary piRNA biogenesis in Drosophila.
EMBO J. 29(19):3301-17A Syd-1 homologue regulates pre- and postsynaptic maturation in Drosophila.
J Cell Biol. 188(4):565-79Characterization of an antagonistic switch between histone H3 lysine 27 methylation and acetylation in the transcriptional regulation of Polycomb group target genes.
Nucleic Acids Res. 38(15):4958-69Peptide labeling with isobaric tags yields higher identification rates using iTRAQ 4-plex compared to TMT 6-plex and iTRAQ 8-plex on LTQ Orbitrap.
Anal Chem. 82(15):6549-58Drosophila genome-wide obesity screen reveals hedgehog as a determinant of brown versus white adipose cell fate.
Cell. 140(1):148-60The Trithorax group protein Ash2l and Saf-A are recruited to the inactive X chromosome at the onset of stable X inactivation.
Development. 137(6):935-43Growth retardation, impaired triacylglycerol catabolism, hepatic steatosis, and lethal skin barrier defect in mice lacking comparative gene identification-58 (CGI-58).
J Biol Chem. 285(10):7300-11Tumor stroma-derived TGF-beta limits myc-driven lymphomagenesis via Suv39h1-dependent senescence.
Cancer Cell. 17(3):262-72The actin cytoskeleton in whole mount preparations and sections.
Methods Cell Biol. 96:529-64Mitogen-inducible gene-6 is a negative regulator of epidermal growth factor receptor signaling in hepatocytes and human hepatocellular carcinoma.
Hepatology. 51(4):1383-90Sex peptide receptor and neuronal TOR/S6K signaling modulate nutrient balancing in Drosophila.
Curr Biol. 20(11):1000-5Transcriptional repression of ceramide kinase in LPS-challenged macrophages.
Biochem Biophys Res Commun. 401(1):164-7Casein kinase 1 is required for efficient removal of Rec8 during meiosis I.
Cell Cycle. 9(13):2657-62High-throughput knockout screen in Schizosaccharomyces pombe identifies a novel gene required for efficient homolog disjunction during meiosis I.
Cell Cycle. 9(9):1802-8Laser microsurgery provides evidence for merotelic kinetochore attachments in fission yeast cells lacking Pcs1 or Clr4.
Cell Cycle. 9(19):3997-4004The zinc-finger protein MAZR is part of the transcription factor network that controls the CD4 versus CD8 lineage fate of double-positive thymocytes.
Nat Immunol. 11(5):442-8Molecular transformers in the cell: lessons learned from the DegP protease-chaperone.
Curr Opin Struct Biol. 20(2):253-8Cortical domain correction repositions the polarity boundary to match the cytokinesis furrow in C. elegans embryos.
Development. 137(10):1743-53Live-cell imaging RNAi screen identifies PP2A-B55alpha and importin-beta1 as key mitotic exit regulators in human cells.
Nat Cell Biol. 12(9):886-93Systematic genetic analysis of muscle morphogenesis and function in Drosophila.
Nature. 464(7286):287-91Topology and organization of the Salmonella typhimurium type III secretion needle complex components.
PLoS Pathog. 6(4):e1000824RhoL controls invasion and Rap1 localization during immune cell transmigration in Drosophila.
Nat Cell Biol. 12(6):605-10Distinct protein domains and expression patterns confer divergent axon guidance functions for Drosophila Robo receptors.
Cell. 140(3):409-20Proteomic analysis of endosomes from genetically modified p14/MP1 mouse embryonic fibroblasts.
Proteomics. 10(22):4117-27Proteomic analysis of endosomes from genetically modified p14/MP1 mouse embryonic fibroblasts.
Proteomics.Disease-associated mutations in TUBA1A result in a spectrum of defects in the tubulin folding and heterodimer assembly pathway.
Hum Mol Genet. 19(18):3599-613Electron tomography reveals unbranched networks of actin filaments in lamellipodia.
Nat Cell Biol. 12(5):429-35Mcl-1 is essential for germinal center formation and B cell memory.
Science. 330(6007):1095-9Organization and coordinated assembly of the type III secretion export apparatus.
Proc Natl Acad Sci U S A. 107(41):17745-50An intrinsic mechanism predisposes Foxp3-expressing regulatory T cells to Th2 conversion in vivo.
J Immunol. 185(10):5983-92Sixteen New Cases Contributing to the Characterization of Patients with Distal 22q11.2 Microduplications.
Mol Syndromol. 1(5):246-254Cellular organization of the neural circuit that drives Drosophila courtship behavior.
Curr Biol. 20(18):1602-14Developmental gene regulation in the era of genomics.
Dev Biol. 339(2):230-9Mouse MOV10L1 associates with Piwi proteins and is an essential component of the Piwi-interacting RNA (piRNA) pathway.
Proc Natl Acad Sci U S A. 107(26):11841-6Nuclear beta-catenin induces an early liver progenitor phenotype in hepatocellular carcinoma and promotes tumor recurrence.
Am J Pathol. 176(1):472-81SATB1 defines the developmental context for gene silencing by Xist in lymphoma and embryonic cells.
Dev Cell. 16(4):507-16Cancer progenitors and epigenetic contexts: an Xisting connection.
Epigenetics. 4(8):568-70Expression of activated STAT5 in neoplastic mast cells in systemic mastocytosis: subcellular distribution and role of the transforming oncoprotein KIT D816V.
Am J Pathol. 175(6):2416-29Breast cancer stem cells: eradication by differentiation therapy?
Cell. 138(4):623-5Charting the molecular network of the drug target Bcr-Abl.
Proc Natl Acad Sci U S A. 106(18):7414-9Structural basis of substrate specificity of plant 12-oxophytodienoate reductases.
J Mol Biol. 392(5):1266-77BrainGazer--visual queries for neurobiology research.
IEEE Trans Vis Comput Graph. 15(6):1497-504Automated monitoring to reduce electron microscope downtime.
Ultramicroscopy. 109(11):1389-92Improving Phosphopeptide/Protein Identification Using a New Data Mining Framework for MS/MS Spectra Preprocessing
J Proteomics Bioinform. 2:150-164FLYSNPdb: a high-density SNP database of Drosophila melanogaster.
Nucleic Acids Res. 37(Database issue):D567-70An improved strategy for tandem affinity purification-tagging of Schizosaccharomyces pombe genes.
Proteomics. 9(20):4825-8Turning meiosis into mitosis.
PLoS Biol. 7(6):e1000124Stepwise activation of enhancer and promoter regions of the B cell commitment gene Pax5 in early lymphopoiesis.
Immunity. 30(4):508-20Reprogramming of Xist against the pluripotent state in fusion hybrids.
J Cell Sci. 122(Pt 22):4122-9The dark and the bright side of Stat3: proto-oncogene and tumor-suppressor.
Front Biosci (Landmark Ed). 14:2944-58Induction of autophagy by spermidine promotes longevity.
Nat Cell Biol. 11(11):1305-14Defining a superlens operating regime for imaging fluorescent molecules.
PLoS One. 4(12):e7963RNA-regulated interaction of transportin-1 and exportin-5 with the double-stranded RNA-binding domain regulates nucleocytoplasmic shuttling of ADAR1.
Mol Cell Biol. 29(6):1487-97McsB is a protein arginine kinase that phosphorylates and inhibits the heat-shock regulator CtsR.
Science. 324(5932):1323-7TNFalpha shedding and epidermal inflammation are controlled by Jun proteins.
Genes Dev. 23(22):2663-74Central control of fever and female body temperature by RANKL/RANK.
Nature. 462(7272):505-9Transcriptional networks controlling skeletal development.
Curr Opin Genet Dev. 19(5):437-43Sensory neurons in the Drosophila genital tract regulate female reproductive behavior.
Neuron. 61(4):511-8Peptidic small molecule activators of the stress sensor DegS.
Mol Biosyst. 5(9):980-5Selectivity profiling of DegP substrates and inhibitors.
Bioorg Med Chem. 17(7):2920-4Beyond photobleaching, laser illumination unbinds fluorescent proteins.
J Phys Chem B. 113(15):5225-33Structure of the anaphase-promoting complex/cyclosome interacting with a mitotic checkpoint complex.
Science. 323(5920):1477-81RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci.
Nat Immunol. 10(6):655-64Stoichiometry determination of the MP1-p14 complex using a novel and cost-efficient method to produce an equimolar mixture of standard peptides.
Anal Chem. 81(24):10254-61Dynamic localisation of Ran GTPase during the cell cycle.
BMC Cell Biol. 10:66Mutations in the beta-tubulin gene TUBB2B result in asymmetrical polymicrogyria.
Nat Genet. 41(6):746-52Generation of transgenic axolotls (Ambystoma mexicanum).
Cold Spring Harb Protoc. 2009(8):pdb.prot5264Axolotl (Ambystoma mexicanum) in vitro fertilization.
Cold Spring Harb Protoc. 2009(8):pdb.prot5263A Dam1-based artificial kinetochore is sufficient to promote chromosome segregation in budding yeast.
Nat Cell Biol. 11(9):1109-15High precision quantitative proteomics using iTRAQ on an LTQ Orbitrap: a new mass spectrometric method combining the benefits of all.
J Proteome Res. 8(10):4743-52Axolotl (Ambystoma mexicanum) limb and tail amputation.
Cold Spring Harb Protoc. 2009(8):pdb.prot5267Grafting axolotl (Ambystoma mexicanum) limb skin and cartilage from GFP+ donors to normal hosts.
Cold Spring Harb Protoc. 2009(8):pdb.prot5266Role of cleavage by separase of the Rec8 kleisin subunit of cohesin during mammalian meiosis I.
J Cell Sci. 122(Pt 15):2686-98ILEI requires oncogenic Ras for the epithelial to mesenchymal transition of hepatocytes and liver carcinoma progression.
Oncogene. 28(5):638-50HAUS, the 8-subunit human Augmin complex, regulates centrosome and spindle integrity.
Curr Biol. 19(10):816-26X chromosome inactivation sparked by non-coding RNAs.
RNA Biol. 6(2):94-9Optimizing the performance of tin dioxide microspheres for phosphopeptide enrichment.
Anal Chim Acta. 638(1):51-7Regulation of APC/C activity in oocytes by a Bub1-dependent spindle assembly checkpoint.
Curr Biol. 19(5):369-80Comparative genomics of gene regulation-conservation and divergence of cis-regulatory information.
Curr Opin Genet Dev. 19(6):565-70Structure, function and regulation of the conserved serine proteases DegP and DegS of Escherichia coli.
Res Microbiol. 160(9):660-6Weak but uniform enrichment of the histone variant macroH2A1 along the inactive X chromosome.
Mol Cell Biol. 29(1):150-6Preventing carryover of peptides and proteins in nano LC-MS separations.
Anal Chem. 81(14):5955-60Multiscale analysis of dynamics and interactions of heterochromatin protein 1 by fluorescence fluctuation microscopy.
Biophys J. 97(11):2876-85An innovative method to study target protein-drug interactions by mass spectrometry.
J Med Chem. 52(9):2875-9Genome-wide analysis of Notch signalling in Drosophila by transgenic RNAi.
Nature. 458(7241):987-92Axolotl (Ambystoma mexicanum) embryonic transplantation methods.
Cold Spring Harb Protoc. 2009(8):pdb.prot5265Cohesin is required for higher-order chromatin conformation at the imprinted IGF2-H19 locus.
PLoS Genet. 5(11):e1000739ANNIE: integrated de novo protein sequence annotation.
Nucleic Acids Res. 37(Web Server issue):W435-40H3K27me3 forms BLOCs over silent genes and intergenic regions and specifies a histone banding pattern on a mouse autosomal chromosome.
Genome Res. 19(2):221-33Meiotic chromosome homology search involves modifications of the nuclear envelope protein Matefin/SUN-1.
Cell. 139(5):920-33Cohesin acetylation: from antiestablishment to establishment.
Mol Cell. 34(1):1-2Building sister chromatid cohesion: smc3 acetylation counteracts an antiestablishment activity.
Mol Cell. 33(6):763-74The temporomandibular joint in a rheumatoid arthritis patient after orthodontic treatment.
Angle Orthod. 79(4):804-11The protein tyrosine kinase Tec regulates mast cell function.
Eur J Immunol. 39(11):3228-38Induction of RNA-directed DNA methylation upon decondensation of constitutive heterochromatin.
EMBO Rep. 10(9):1015-21Systemic anti-VEGF treatment strongly reduces skin inflammation in a mouse model of psoriasis.
Proc Natl Acad Sci U S A. 106(50):21264-9The TDRD9-MIWI2 complex is essential for piRNA-mediated retrotransposon silencing in the mouse male germline.
Dev Cell. 17(6):775-87Characterization of the interferon-producing cell in mice infected with Listeria monocytogenes.
PLoS Pathog. 5(3):e1000355Wif-1 is expressed at cartilage-mesenchyme interfaces and impedes Wnt3a-mediated inhibition of chondrogenesis.
J Cell Sci. 122(Pt 20):3627-37Considering the evolution of regeneration in the central nervous system.
Nat Rev Neurosci. 10(10):713-23Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins.
J Biol Chem. 284(13):8395-405Hepatic tumor-stroma crosstalk guides epithelial to mesenchymal transition at the tumor edge.
Oncogene. 28(45):4022-33Ambystoma mexicanum, the axolotl: a versatile amphibian model for regeneration, development, and evolution studies.
Cold Spring Harb Protoc. 2009(8):pdb.emo128The cohesin complex is required for the DNA damage-induced G2/M checkpoint in mammalian cells.
EMBO J. 28(17):2625-35How cohesin and CTCF cooperate in regulating gene expression.
Chromosome Res. 17(2):201-14Regulatory T cell differentiation of thymocytes does not require a dedicated antigen-presenting cell but is under T cell-intrinsic developmental control.
Proc Natl Acad Sci U S A. 106(25):10278-83Phosphoregulation of the budding yeast EB1 homologue Bim1p by Aurora/Ipl1p.
J Cell Biol. 186(3):379-91A guide to accurate measurement of diffusion using fluorescence correlation techniques with blinking quantum dot nanoparticle labels.
J Chem Phys. 128(22):225105Identification of an axonal kinesin-3 motor for fast anterograde vesicle transport that facilitates retrograde transport of neuropeptides.
Mol Biol Cell. 19(1):274-83Systematic identification of genes that regulate neuronal wiring in the Drosophila visual system.
PLoS Genet. 4(5):e1000085Comparative analysis of sequence features involved in the recognition of tandem splice sites.
BMC Genomics. 9:202The tumor suppressors Brat and Numb regulate transit-amplifying neuroblast lineages in Drosophila.
Dev Cell. 14(4):535-46Osteoclast size is controlled by Fra-2 through LIF/LIF-receptor signalling and hypoxia.
Nature. 454(7201):221-5Clustering of VASP actively drives processive, WH2 domain-mediated actin filament elongation.
EMBO J. 27(22):2943-54High-resolution, high-throughput SNP mapping in Drosophila melanogaster.
Nat Methods. 5(4):323-9Developmental plasticity of lymphocytes.
Curr Opin Immunol. 20(2):139-48Mutations in AtPS1 (Arabidopsis thaliana parallel spindle 1) lead to the production of diploid pollen grains.
PLoS Genet. 4(11):e1000274The Drosophila pheromone cVA activates a sexually dimorphic neural circuit.
Nature. 452(7186):473-7Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.
J Proteome Res. 7(6):2458-70Wired for sex: the neurobiology of Drosophila mating decisions.
Science. 322(5903):904-9Podoplanin is a novel fos target gene in skin carcinogenesis.
Cancer Res. 68(17):6877-83Development of pulmonary fibrosis through a pathway involving the transcription factor Fra-2/AP-1.
Proc Natl Acad Sci U S A. 105(30):10525-30Expression and regulation of HTRA1 during chick and early mouse development.
Dev Dyn. 237(7):1893-900Role of Growth factors in Bone development and differentiation.
In: The Skeletal System. Ed. Pourquie, O. Cold Spring Harbor Laboratory Press, New York. Chapter:8Sustained TGF beta exposure suppresses Smad and non-Smad signalling in mammary epithelial cells, leading to EMT and inhibition of growth arrest and apoptosis.
Oncogene. 27(9):1218-30When flies and mice develop cancer. Meeting on development and cancer.
EMBO Rep. 9(8):730-4Redundant mechanisms for regulation of midline crossing in Drosophila.
PLoS One. 3(11):e3798Stat5 activation enables erythropoiesis in the absence of EpoR and Jak2.
Blood. 111(9):4511-22Igbp1 is part of a positive feedback loop in stem cell factor-dependent, selective mRNA translation initiation inhibiting erythroid differentiation.
Blood. 112(7):2750-60Di-methyl H4 lysine 20 targets the checkpoint protein Crb2 to sites of DNA damage.
J Biol Chem. 283(48):33168-74The Dam1 ring binds microtubules strongly enough to be a processive as well as energy-efficient coupler for chromosome motion.
Proc Natl Acad Sci U S A. 105(40):15423-8Different assemblies of the DAM1 complex follow shortening microtubules by distinct mechanisms.
Proc Natl Acad Sci U S A. 105(19):6918-23Gata3 acts downstream of beta-catenin signaling to prevent ectopic metanephric kidney induction.
PLoS Genet. 4(12):e1000316Lack of nuclear factor-kappa B2/p100 causes a RelB-dependent block in early B lymphopoiesis.
Blood. 112(3):551-9Targeting c-Jun and JunB proteins as potential anticancer cell therapy.
Oncogene. 27(5):641-52JunB Inhibits ER Stress and Apoptosis in Pancreatic Beta Cells.
PLoS One. 3(8):e3030The role of the transcription factor AP-1 in colitis-associated and beta-catenin-dependent intestinal tumorigenesis in mice.
Oncogene. 27(47):6102-9Transcriptional regulation of EGR-1 by the interleukin-1-JNK-MKK7-c-Jun pathway.
J Biol Chem. 283(18):12120-8Strategies for identifying RNA splicing regulatory motifs and predicting alternative splicing events.
PLoS Comput Biol. 4(1):e21Proliferation of human HCC cells and chemically induced mouse liver cancers requires JNK1-dependent p21 downregulation.
J Clin Invest.Proliferation of human HCC cells and chemically induced mouse liver cancers requires JNK1-dependent p21 downregulation.
J Clin Invest. 118(12):3943-53Disruption of c-Jun reduces cellular migration and invasion through inhibition of c-Src and hyperactivation of ROCK II kinase.
Mol Biol Cell. 19(4):1378-90GraFix: sample preparation for single-particle electron cryomicroscopy.
Nat Methods. 5(1):53-5JunD suppresses bone formation and contributes to low bone mass induced by estrogen depletion.
J Cell Biochem. 103(4):1037-45Stat5 regulates cellular iron uptake of erythroid cells via IRP-2 and TfR-1.
Blood. 112(9):3878-88The Suv39h-HP1 histone methylation pathway is dispensable for enrichment and protection of cohesin at centromeres in mammalian cells.
Chromosoma. 117(2):199-210EGFR signalling as a negative regulator of Notch1 gene transcription and function in proliferating keratinocytes and cancer.
Nat Cell Biol. 10(8):902-11The different functions of Stat5 and chromatin alteration through Stat5 proteins.
Front Biosci. 13:6237-54Novel insights into the flexibility of cell and positional identity during urodele limb regeneration.
Cold Spring Harb Symp Quant Biol. 73:583-92Interplay of PDZ and protease domain of DegP ensures efficient elimination of misfolded proteins.
Proc Natl Acad Sci U S A. 105(22):7702-7Structural basis for the regulated protease and chaperone function of DegP.
Nature. 453(7197):885-90Instructive role of the transcription factor E2A in early B lymphopoiesis and germinal center B cell development.
Immunity. 28(6):751-62Complications of needle electromyography: hematoma risk and correlation with anticoagulation and antiplatelet therapy.
Muscle Nerve. 38(4):1225-30SHOC1, an XPF endonuclease-related protein, is essential for the formation of class I meiotic crossovers.
Curr Biol. 18(18):1432-7Epidermal JunB represses G-CSF transcription and affects haematopoiesis and bone formation.
Nat Cell Biol. 10(8):1003-11Allosteric activation of HtrA protease DegP by stress signals during bacterial protein quality control.
Angew Chem Int Ed Engl. 47(7):1332-4Epithelial Plasticity of Hepatocytes During Liver Tumor Progression
Stem Cells and their Potential for Clinical Application . :123-135DNA double-strand breaks, but not crossovers, are required for the reorganization of meiotic nuclei in Tetrahymena.
J Cell Sci. 121(Pt 13):2148-58Loss of nucleoplasmic LAP2alpha-lamin A complexes causes erythroid and epidermal progenitor hyperproliferation.
Nat Cell Biol. 10(11):1341-8Autophagy in thymic epithelium shapes the T-cell repertoire and is essential for tolerance.
Nature. 455(7211):396-400Mei-P26 regulates microRNAs and cell growth in the Drosophila ovarian stem cell lineage.
Nature. 454(7201):241-5PR-SET7 and SUV4-20H regulate H4 lysine-20 methylation at imprinting control regions in the mouse.
EMBO Rep. 9(10):998-1005Cell-type-specific TEV protease cleavage reveals cohesin functions in Drosophila neurons.
Dev Cell. 14(2):239-51The cohesin complex and its roles in chromosome biology.
Genes Dev. 22(22):3089-114Polo on the Rise-from Mitotic Entry to Cytokinesis with Plk1.
Dev Cell. 14(5):646-59Differential transcriptional modulation of biological processes in adipocyte triglyceride lipase and hormone-sensitive lipase-deficient mice.
Genomics. 92(1):26-32BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals.
Nat Methods. 5(5):409-15Arabidopsis SMG7 protein is required for exit from meiosis.
J Cell Sci. 121(Pt 13):2208-16Efficient adult skeletal muscle regeneration in mice deficient in p38beta, p38gamma and p38delta MAP kinases.
Cell Cycle. 7(14):2208-14Cellular repressor of E1A-stimulated genes is a bona fide lysosomal protein which undergoes proteolytic maturation during its biosynthesis.
Exp Cell Res. 314(16):3036-47Enhanced detection and identification of multiply phosphorylated peptides using TiO2 enrichment in combination with MALDI TOF/TOF MS.
Proteomics. 8(21):4577-92Positional cloning by fast-track SNP-mapping in Drosophila melanogaster.
Nat Protoc. 3(11):1751-65A chromatin-wide transition to H4K20 monomethylation impairs genome integrity and programmed DNA rearrangements in the mouse.
Genes Dev. 22(15):2048-61Synergy of Eed and Tsix in the repression of Xist gene and X-chromosome inactivation.
EMBO J. 27(13):1816-26Unravelling the structure of the lamellipodium.
J Microsc. 231(3):479-85Longitudinal alteration of the occlusal plane and development of different dentoskeletal frames during growth.
Am J Orthod Dentofacial Orthop. 134(5):602.e1-11; discussion 602-3Heads or tails: can Wnt tell which one is up?
Nat Cell Biol. 10(2):122-4Ca2+/Calmodulin-dependent kinase II signaling causes skeletal overgrowth and premature chondrocyte maturation.
Dev Biol. 317(1):132-46Polo and Aurora kinases: lessons derived from chemical biology.
Curr Opin Cell Biol. 20(1):77-84The transmembrane protein Golden goal regulates R8 photoreceptor axon-axon and axon-target interactions.
Neuron. 57(5):691-704Twenty years of cell-cycle conferences in Roscoff.
Nat Cell Biol. 10(8):877-80Antagonistic control of cell fates by JNK and p38-MAPK signaling.
Cell Death Differ. 15(1):89-93Developmentally informed research on the effectiveness of clinical trials: a primer for assessing how developmental issues may influence treatment responses among adolescents with alcohol use problems.
Pediatrics. 121 Suppl 4:S337-47Architecture and flexibility of the yeast Ndc80 kinetochore complex.
J Mol Biol. 383(4):894-903Cohesin mediates transcriptional insulation by CCCTC-binding factor.
Nature. 451(7180):796-80114-3-3 proteins recognize a histone code at histone H3 and are required for transcriptional activation.
EMBO J. 27(1):88-99c-Jun controls histone modifications, NF-kappaB recruitment, and RNA polymerase II function to activate the ccl2 gene.
Mol Cell Biol. 28(13):4407-23A receptor that mediates the post-mating switch in Drosophila reproductive behaviour.
Nature. 451(7174):33-7Identification of the human homolog of the imprinted mouse Air non-coding RNA.
Genomics. 92(6):464-73Activator protein 1 (Fos/Jun) functions in inflammatory bone and skin disease.
Arthritis Res Ther. 10(1):201The transcription factor ZEB1 (deltaEF1) promotes tumour cell dedifferentiation by repressing master regulators of epithelial polarity.
Oncogene. 26(49):6979-88The transcription factor ZEB1 (deltaEF1) represses Plakophilin 3 during human cancer progression.
FEBS Lett. 581(8):1617-24Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch.
Immunity. 27(1):89-99ApoER2/VLDL receptor and Dab1 in the rostral migratory stream function in postnatal neuronal migration independently of Reelin.
Proc Natl Acad Sci U S A. 104(20):8508-13Selection of Foxp3+ regulatory T cells specific for self antigen expressed and presented by Aire+ medullary thymic epithelial cells.
Nat Immunol. 8(4):351-8Role of heterodimerization of c-Fos and Fra1 proteins in osteoclast differentiation.
Bone. 40(4):867-75Differential regulation of Foxo3a target genes in erythropoiesis.
Mol Cell Biol. 27(10):3839-3854Suv4-20h deficiency results in telomere elongation and derepression of telomere recombination.
J Cell Biol. 178(6):925-36In vitro differentiation of murine embryonic stem cells toward a renal lineage.
Differentiation. 75(5):337-49Identification of new targets using expression profiling.
In Antiangiogenic cancer therapy (Davis, D.R., Herbst, R.S., & Abbruzzese, J.L., eds.); CRC Press Taylor & Francis Group, Boca Raton London New York.. :415-41Fra-1 promotes growth and survival in RAS-transformed thyroid cells by controlling cyclin A transcription.
EMBO J. 26(7):1878-90Conversion of mature B cells into T cells by dedifferentiation to uncommitted progenitors.
Nature. 449(7161):473-7Pax5: the guardian of B cell identity and function.
Nat Immunol. 8(5):463-70Ran and Rac in mouse eggs: cortical polarity and spindle positioning.
Dev Cell. 12(2):174-6Acto-myosin reorganization and PAR polarity in C. elegans.
Development. 134(6):1035-43A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila.
Nature. 448(7150):151-6Simultaneous generation of fra-2 conditional and fra-2 knock-out mice.
Genesis. 45(7):447-51PSD-95 is required for activity-driven synapse stabilization.
Proc Natl Acad Sci U S A. 104(10):4176-81The ring between ring fingers (RBR) protein family.
Genome Biol. 8(3):209Posttranslational modifications and subcellular localization signals: indicators of sequence regions without inherent 3D structure?
Curr Protein Pept Sci. 8(2):197-203Direct glucocorticoid receptor-Stat5 interaction in hepatocytes controls body size and maturation-related gene expression.
Genes Dev. 21(10):1157-62PDGF essentially links TGF-beta signaling to nuclear beta-catenin accumulation in hepatocellular carcinoma progression.
Oncogene. 26(23):3395-405Reporter gene insertions reveal a strictly B lymphoid-specific expression pattern of Pax5 in support of its B cell identity function.
J Immunol. 178(12):8222-8Reporter gene insertions reveal a strictly B lymphoid-specific expression pattern of Pax5 in support of its B cell identity function.
J Immunol. 178(5):3031-7Beta-catenin/LEF-1 signalling in breast cancer--central players activated by a plethora of inputs.
Cells Tissues Organs. 185(1-3):51-60The 20S proteasome isolated from Alzheimer's disease brain shows post-translational modifications but unchanged proteolytic activity.
J Neurochem. 101(6):1483-90Tandem affinity purification of functional TAP-tagged proteins from human cells.
Nat Protoc. 2(5):1145-51The kinetochore proteins Pcs1 and Mde4 and heterochromatin are required to prevent merotelic orientation.
Curr Biol. 17(14):1190-200The origins of oncomice: a history of the first transgenic mice genetically engineered to develop cancer.
Genes Dev. 21(18):2258-70Constitutive activation of Stat5 promotes its cytoplasmic localization and association with PI3-kinase in myeloid leukemias.
Blood. 109(4):1678-86MASPECTRAS: a platform for management and analysis of proteomics LC-MS/MS data.
BMC Bioinformatics. 8:197Regulation of the sigmaE stress response by DegS: how the PDZ domain keeps the protease inactive in the resting state and allows integration of different OMP-derived stress signals upon folding stress.
Genes Dev. 21(20):2659-70Hepatocyte survival in acute hepatitis is due to c-Jun/AP-1-dependent expression of inducible nitric oxide synthase.
Proc Natl Acad Sci U S A. 104(43):17105-10Dscam diversity is essential for neuronal wiring and self-recognition.
Nature. 449(7159):223-7Tumor progression induced by the loss of E-cadherin independent of beta-catenin/Tcf-mediated Wnt signaling.
Oncogene. 26(16):2290-8p53 is regulated by the lysine demethylase LSD1.
Nature. 449(7158):105-8p38alpha suppresses normal and cancer cell proliferation by antagonizing the JNK-c-Jun pathway.
Nat Genet. 39(6):741-9p38alpha: a suppressor of cell proliferation and tumorigenesis.
Cell Cycle. 6(20):2429-33A physical assay for sister chromatid cohesion in vitro.
Mol Cell. 27(2):300-10Caenorhabditis elegans prom-1 is required for meiotic prophase progression and homologous chromosome pairing.
Mol Biol Cell. 18(12):4911-20A systematic comparative and structural analysis of protein phosphorylation sites based on the mtcPTM database.
Genome Biol. 8(5):R90Molecular basis for skeletal variation: insights from developmental genetic studies in mice.
Birth Defects Res B Dev Reprod Toxicol. 80(6):425-50Somatic excision demonstrates that c-Jun induces cellular migration and invasion through induction of stem cell factor.
Mol Cell Biol. 27(4):1356-69Drosophila olfactory memory: single genes to complex neural circuits.
Nat Rev Neurosci. 8(5):341-54Function of the Drosophila CPEB protein Orb2 in long-term courtship memory.
Nat Neurosci. 10(12):1587-93Impaired heart contractility in Apelin gene-deficient mice associated with aging and pressure overload.
Circ Res. 101(4):e32-42Reversal of H3K9me2 by a small-molecule inhibitor for the G9a histone methyltransferase.
Mol Cell. 25(3):473-81A single class of olfactory neurons mediates behavioural responses to a Drosophila sex pheromone.
Nature. 446(7135):542-6Ring1B is crucial for the regulation of developmental control genes and PRC1 proteins but not X inactivation in embryonic cells.
J Cell Biol. 178(2):219-29The small-molecule inhibitor BI 2536 reveals novel insights into mitotic roles of polo-like kinase 1.
Curr Biol. 17(4):304-15Aurora B controls the association of condensin I but not condensin II with mitotic chromosomes.
J Cell Sci. 120(Pt 7):1245-55Plasticity of mammalian myotubes upon stimulation with a thrombin-activated serum factor.
Cell Cycle. 6(9):1096-101HOXA10 is a critical regulator for hematopoietic stem cells and erythroid/megakaryocyte development.
Blood. 109(9):3687-96Life beyond cleavage: the case of Ago2 and hematopoiesis.
Genes Dev. 21(16):1983-8Towards complete sets of farnesylated and geranylgeranylated proteins.
PLoS Comput Biol. 3(4):e66Titanium dioxide as a chemo-affinity solid phase in offline phosphopeptide chromatography prior to HPLC-MS/MS analysis.
Nat Protoc. 2(5):1059-69DNA methylation and complete transcriptional silencing of cancer genes persist after depletion of EZH2.
Cancer Res. 67(11):5097-102A clonal analysis of neural progenitors during axolotl spinal cord regeneration reveals evidence for both spatially restricted and multipotent progenitors.
Development. 134(11):2083-93LAP2alpha-binding protein LINT-25 is a novel chromatin-associated protein involved in cell cycle exit.
J Cell Sci. 120(Pt 5):737-47The complete removal of cohesin from chromosome arms depends on separase.
J Cell Sci. 120(Pt 23):4188-96pkaPS: prediction of protein kinase A phosphorylation sites with the simplified kinase-substrate binding model.
Biol Direct. 2:1Xist and the order of silencing.
EMBO Rep. 8(1):34-9Locked nucleic acid-based in situ detection of microRNAs in mouse tissue sections.
Nat Protoc. 2(6):1508-14A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing.
Nat Genet. 39(2):237-42JunB is a gatekeeper for B-lymphoid leukemia.
Oncogene. 26(33):4863-71A chemical proteomics approach to phosphatidylinositol 3-kinase signaling in macrophages.
Mol Cell Proteomics. 6(11):1829-41A conserved function for a Caenorhabditis elegans Com1/Sae2/CtIP protein homolog in meiotic recombination.
EMBO J. 26(24):5071-82The nuclear envelope protein Matefin/SUN-1 is required for homologous pairing in C. elegans meiosis.
Dev Cell. 12(6):873-85Genetic analysis of p38 MAP kinases in myogenesis: fundamental role of p38alpha in abrogating myoblast proliferation.
EMBO J. 26(5):1245-56Polo-like kinase 1 triggers the initiation of cytokinesis in human cells by promoting recruitment of the RhoGEF Ect2 to the central spindle.
Dev Cell. 12(5):713-25c-Myc is required for transformation of FDC-P1 cells by EGFRvIII.
FEBS Lett. 581(13):2549-56Active and repressive chromatin are interspersed without spreading in an imprinted gene cluster in the mammalian genome.
Mol Cell. 27(3):353-66Distinct promoters mediate the regulation of Ebf1 gene expression by interleukin-7 and Pax5.
Mol Cell Biol. 27(2):579-94Heterochromatin formation in Drosophila is initiated through active removal of H3K4 methylation by the LSD1 homolog SU(VAR)3-3.
Mol Cell. 26(1):103-15Transcription factor Pax5 activates the chromatin of key genes involved in B cell signaling, adhesion, migration, and immune function.
Immunity. 27(1):49-63Spatial organization of a ubiquitous eukaryotic kinetochore protein network in Drosophila chromosomes.
Chromosoma. 116(4):385-402Sororin is required for stable binding of cohesin to chromatin and for sister chromatid cohesion in interphase.
Curr Biol. 17(7):630-6The transmembrane protein Kon-tiki couples to Dgrip to mediate myotube targeting in Drosophila.
Dev Cell. 12(5):751-66Annexin A2/P11 interaction: new insights into annexin A2 tetramer structure by chemical crosslinking, high-resolution mass spectrometry, and computational modeling.
Proteins. 69(2):254-69Reversible contraction by looping of the Tcra and Tcrb loci in rearranging thymocytes.
Nat Immunol. 8(4):378-87Oncogenic role of Pax5 in the T-lymphoid lineage upon ectopic expression from the immunoglobulin heavy-chain locus.
Blood. 109(1):281-9BI 2536, a potent and selective inhibitor of polo-like kinase 1, inhibits tumor growth in vivo.
Curr Biol. 17(4):316-22Temporal target restriction of olfactory receptor neurons by Semaphorin-1a/PlexinA-mediated axon-axon interactions.
Neuron. 53(2):185-200Mammalian Polycomb Scmh1 mediates exclusion of Polycomb complexes from the XY body in the pachytene spermatocytes.
Development. 134(3):579-90Signal transducer and activator of transcription 3 activation promotes invasive growth of colon carcinomas through matrix metalloproteinase induction.
Neoplasia. 9(4):279-91A novel plant gene essential for meiosis is related to the human CtIP and the yeast COM1/SAE2 gene.
EMBO J. 26(24):5061-70Role of the polycomb repressive complex 2 in acute promyelocytic leukemia.
Cancer Cell. 11(6):513-25Infarct volume after transient middle cerebral artery occlusion (MCAo) can be reduced by attenuation but not by inactivation of c-Jun action.
Brain Res. 1151:12-9Molecular biology. How and when the genome sticks together.
Science. 317(5835):209-10RNA degradation in fission yeast mitochondria is stimulated by a member of a new family of proteins that are conserved in lower eukaryotes.
J Mol Biol. 367(3):681-91Dimer composition and promoter context contribute to functional cooperation between AP-1 and NFAT.
J Mol Biol. 371(3):569-76Cooperative demethylation by JMJD2C and LSD1 promotes androgen receptor-dependent gene expression.
Nat Cell Biol. 9(3):347-53NF-kappaB p50 and p52 regulate receptor activator of NF-kappaB ligand (RANKL) and tumor necrosis factor-induced osteoclast precursor differentiation by activating c-Fos and NFATc1.
J Biol Chem. 282(25):18245-18253The calmodulin pathway and evolution of elongated beak morphology in Darwin's finches.
Nature. 442(7102):563-7Epigenetics
Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York..Cohesin's ATPase activity is stimulated by the C-terminal Winged-Helix domain of its kleisin subunit.
Curr Biol. 16(20):1998-2008Efficient method to generate single-copy transgenic mice by site-specific integration in embryonic stem cells.
Genesis. 44(1):23-8Protein prenylation: an (almost) comprehensive overview on discovery history, enzymology and significance in physiology and disease.
Chemical Monthly. 137:1241-1281Farnesylation or geranylgeranylation? Efficient assays for testing protein prenylation in vitro and in vivo.
BMC Biochem. 7:6Wiring stability of the adult Drosophila olfactory circuit after lesion.
J Neurosci. 26(13):3367-76Asymmetric segregation of the tumor suppressor brat regulates self-renewal in Drosophila neural stem cells.
Cell. 124(6):1241-53The Drosophila NuMA Homolog Mud regulates spindle orientation in asymmetric cell division.
Dev Cell. 10(6):731-42The histone methyltransferase Suv39h1 increases class switch recombination specifically to IgA.
J Immunol. 177(2):1179-88Netrins guide Drosophila commissural axons at short range.
Nat Neurosci. 9(2):188-94Crystal structure of 12-oxophytodienoate reductase 3 from tomato: self-inhibition by dimerization.
Proc Natl Acad Sci U S A. 103(39):14337-42Histone modification patterns associated with the human X chromosome.
EMBO Rep. 7(6):628-34Epigenetic control of lymphopoiesis.
In Epigenetics (Allis, Jenuwein, Reinberg, eds.); Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York.. :397-414A novel role for Xist RNA in the formation of a repressive nuclear compartment into which genes are recruited when silenced.
Genes Dev. 20(16):2223-37Phosphoproteomics as a tool to unravel plant regulatory mechanisms
Physiologia Plantarum . 126(1):110-119Gene repression by Pax5 in B cells is essential for blood cell homeostasis and is reversed in plasma cells.
Immunity. 24(3):269-81Regulation of commissural axon pathfinding by slit and its Robo receptors.
Annu Rev Cell Dev Biol. 22:651-75Erythroid progenitor renewal versus differentiation: genetic evidence for cell autonomous, essential functions of EpoR, Stat5 and the GR.
Oncogene. 25(20):2890-900Histone modification and the control of heterochromatic gene silencing in Drosophila.
Chromosome Res. 14(4):377-92The polycomb group protein EZH2 is required for mammalian circadian clock function.
J Biol Chem. 281(30):21209-21215Jmjd2b antagonizes H3K9 trimethylation at pericentric heterochromatin in mammalian cells.
Genes Dev. 20(12):1557-62Distinct roles of Polycomb group gene products in transcriptionally repressed and active domains of Hoxb8.
Development. 133(12):2371-81Condensin I stabilizes chromosomes mechanically through a dynamic interaction in live cells.
Curr Biol. 16(4):333-44Live-cell imaging reveals a stable cohesin-chromatin interaction after but not before DNA replication.
Curr Biol. 16(15):1571-8A crucial function of PDGF in TGF-beta-mediated cancer progression of hepatocytes.
Oncogene. 25(22):3170-85The role of human HtrA1 in arthritic disease.
J Biol Chem. 281(10):6124-9High-throughput knockout screen in fission yeast.
Nat Protoc. 1(5):2457-64Pax 2/8-regulated Gata 3 expression is necessary for morphogenesis and guidance of the nephric duct in the developing kidney.
Development. 133(1):53-61Evidence that loading of cohesin onto chromosomes involves opening of its SMC hinge.
Cell. 127(3):523-37Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase.
Science. 312(5774):734-7Bone and Cartilage.
Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine (Ganten, Ruckpaul, eds.). :155-9Acetylation and MAPK phosphorylation cooperate to regulate the degradation of active GATA-1.
EMBO J. 25(14):3264-74Microscopy of the Drosophila facet eye: vademecum for standardized fixation, embedding, and sectioning.
Microsc Res Tech. 69(2):93-8Multiple roles of mesenchymal beta-catenin during murine limb patterning.
Development. 133(7):1219-29Structural analysis of the ZEN-4/CeMKLP1 motor domain and its interaction with microtubules.
J Struct Biol. 153(1):73-84Clarifying the role of Stat5 in lymphoid development and Abelson-induced transformation.
Blood. 107(12):4898-906Repression of p53 activity by Smyd2-mediated methylation.
Nature. 444(7119):629-32Mitotic activation of the kinase Aurora-A requires its binding partner Bora.
Dev Cell. 11(2):147-57Isotope-labeled cross-linkers and Fourier transform ion cyclotron resonance mass spectrometry for structural analysis of a protein/peptide complex.
J Am Soc Mass Spectrom. 17(8):1100-1113Raf plus TGFbeta-dependent EMT is initiated by endocytosis and lysosomal degradation of E-cadherin.
Oncogene. 25(54):7117-30Autocrine PDGFR signaling promotes mammary cancer metastasis.
J Clin Invest. 116(6):1561-70Regulation of cancer cell migration and bone metastasis by RANKL.
Nature. 440(7084):692-6STAT1 acts as a tumor promoter for leukemia development.
Cancer Cell. 10(1):77-87Methods to measure ubiquitin-dependent proteolysis mediated by the anaphase-promoting complex.
Methods. 38(1):39-51The role of histone modifications in epigenetic transitions during normal and perturbed development.
Ernst Schering Res Found Workshop. (57):1-27Resolution of chiasmata in oocytes requires separase-mediated proteolysis.
Cell. 126(1):135-46Wapl controls the dynamic association of cohesin with chromatin.
Cell. 127(5):955-67Shared neural circuitry for female and male sexual behaviours in Drosophila.
Curr Biol. 16(10):R355-6Checkpoint activation: don't get mad too much.
Curr Biol. 16(11):R412-4Cleavage of the siRNA passenger strand during RISC assembly in human cells.
EMBO Rep. 7(3):314-20Silenced tumor suppressor genes reactivated by DNA demethylation do not return to a fully euchromatic chromatin state.
Cancer Res. 66(7):3541-9HPLC techniques for proteomics analysis--a short overview of latest developments.
Brief Funct Genomic Proteomic. 5(4):249-60Phosphoproteomics strategies for the functional analysis of signal transduction.
Proteomics. 6(14):4047-56Cleaning of raw peptide MS/MS spectra: improved protein identification following deconvolution of multiply charged peaks, isotope clusters, and removal of background noise.
Proteomics. 6(19):5117-31DOUTfinder--identification of distant domain outliers using subsignificant sequence similarity.
Nucleic Acids Res. 34(Web Server issue):W214-8Post-transcriptional regulation of microRNA expression.
RNA. 12(7):1161-7The anaphase promoting complex/cyclosome: a machine designed to destroy.
Nat Rev Mol Cell Biol. 7(9):644-56Monopolar attachment of sister kinetochores at meiosis I requires casein kinase 1.
Cell. 126(6):1049-64T-bet negatively regulates autoimmune myocarditis by suppressing local production of interleukin 17.
J Exp Med. 203(8):2009-19Electron Microscopy of Extracted Cytoskeletons: Negative Staining, Cryoelectron Microscopy and Correlation with Light Microscopy.
Cell Biology - A Laboratory Handbook (J. E. Celis, ed.).Protein phosphatase 2A protects centromeric sister chromatid cohesion during meiosis I.
Nature. 441(7089):53-61A balance between Raf-1 and Fas expression sets the pace of erythroid differentiation.
Blood. 108(1):152-9Hematopoietic precursor cells transiently reestablish permissiveness for X inactivation.
Mol Cell Biol. 26(19):7167-77Application of a sensitive collection heuristic for very large protein families: evolutionary relationship between adipose triglyceride lipase (ATGL) and classic mammalian lipases.
BMC Bioinformatics. 7:164Recruitment of PRC1 function at the initiation of X inactivation independent of PRC2 and silencing.
EMBO J. 25(13):3110-22Remodeling the regulation of iron metabolism during erythroid differentiation to ensure efficient heme biosynthesis.
Blood. 107(10):4159-67Silencing by plant Polycomb-group genes requires dispersed trimethylation of histone H3 at lysine 27.
EMBO J. 25(19):4638-49Mutant nuclear lamin A leads to progressive alterations of epigenetic control in premature aging.
Proc Natl Acad Sci U S A. 103(23):8703-8A germline GFP transgenic axolotl and its use to track cell fate: dual origin of the fin mesenchyme during development and the fate of blood cells during regeneration.
Dev Biol. 290(2):386-97Role of canonical Wnt-signalling in joint formation.
Eur Cell Mater. 12:71-80Wnt9a signaling is required for joint integrity and regulation of Ihh during chondrogenesis.
Development. 133(15):3039-49Filopodia formation in the absence of functional WAVE- and Arp2/3-complexes.
Mol Biol Cell. 17(6):2581-91c-Jun/AP-1 controls liver regeneration by repressing p53/p21 and p38 MAPK activity.
Genes Dev. 20(16):2306-14Application of different fragmentation techniques for the analysis of phosphopeptides using a hybrid linear ion trap-FTICR mass spectrometer.
Biochim Biophys Acta. 1764(12):1842-52Reversibility of the differentiated state: regeneration in amphibians.
Artif Organs. 30(10):743-55The mechanism of repression of the myeloid-specific c-fms gene by Pax5 during B lineage restriction.
EMBO J. 25(5):1070-80p14-MP1-MEK1 signaling regulates endosomal traffic and cellular proliferation during tissue homeostasis.
J Cell Biol. 175(6):861-8The adaptor protein X11Lalpha/Dmint1 interacts with the PDZ-binding domain of the cell recognition protein Rst in Drosophila.
Dev Biol. 289(2):296-307fruitless regulates aggression and dominance in Drosophila.
Nat Neurosci. 9(12):1469-71ILEI: a cytokine essential for EMT, tumor formation, and late events in metastasis in epithelial cells.
Cancer Cell. 10(3):227-39Neuronal survival depends on EGFR signaling in cortical but not midbrain astrocytes.
EMBO J. 25(4):752-62Human Scc4 is required for cohesin binding to chromatin, sister-chromatid cohesion, and mitotic progression.
Curr Biol. 16(9):863-74Postnatal development of the murine cerebellar cortex: formation and early dispersal of basket, stellate and Golgi neurons.
Eur J Neurosci. 24(2):466-78Separase: a universal trigger for sister chromatid disjunction but not chromosome cycle progression.
J Cell Biol. 172(6):847-60Sexual behaviour: do a few dead neurons make the difference?
Curr Biol. 16(1):R23-5Jun signalling in the epidermis: From developmental defects to psoriasis and skin tumors.
Int J Biochem Cell Biol. 38(7):1043-9AP-1 dimers regulate transcription of the p14/p19ARF tumor suppressor gene.
Oncogene. 24(14):2298-306Thyroid hormone T3 acting through the thyroid hormone alpha receptor is necessary for implementation of erythropoiesis in the neonatal spleen environment in the mouse.
Development. 132(5):925-34Rapid in vivo analysis of mutant forms of the LAT adaptor using Pax5-Lat double-deficient pro-B cells.
Eur J Immunol. 35(3):977-86Autoamplification of NFATc1 expression determines its essential role in bone homeostasis.
J Exp Med. 202(9):1261-9Initiation of epigenetic reprogramming of the X chromosome in somatic nuclei transplanted to a mouse oocyte.
EMBO Rep. 6(8):748-54The limited role of NH2-terminal c-Jun phosphorylation in neuronal apoptosis: identification of the nuclear pore complex as a potential target of the JNK pathway.
J Cell Biol. 170(3):401-11Phosphorylation-induced autoinhibition regulates the cytoskeletal protein Lethal (2) giant larvae.
Curr Biol. 15(3):276-82Localization-dependent and -independent roles of numb contribute to cell-fate specification in Drosophila.
Curr Biol. 15(17):1583-90Expression of a natural tumor antigen by thymic epithelial cells impairs the tumor-protective CD4+ T-cell repertoire.
Cancer Res. 65(14):6443-9Identification of Pax2-regulated genes by expression profiling of the mid-hindbrain organizer region.
Development. 132(11):2633-43Oncogene-induced senescence as an initial barrier in lymphoma development.
Nature. 436(7051):660-5Specific pathophysiological functions of JNK isoforms in the brain.
Eur J Neurosci. 21(2):363-77Persistent STAT3 activation in colon cancer is associated with enhanced cell proliferation and tumor growth.
Neoplasia. 7(6):545-55Development and function of agonist-induced CD25+Foxp3+ regulatory T cells in the absence of interleukin 2 signaling.
Nat Immunol. 6(11):1152-9Genotyping of Toxoplasma gondii strains isolated from dogs with neurological signs.
Vet Parasitol. 127(1):23-7Essential role of RSK2 in c-Fos-dependent osteosarcoma development.
J Clin Invest. 115(3):664-72Expansion and differentiation of immature mouse and human hematopoietic progenitors.
Methods Mol Med. 105:323-44The erythroid phenotype of EKLF-null mice: defects in hemoglobin metabolism and membrane stability.
Mol Cell Biol. 25(12):5205-14Localization of the coactivator Cdh1 and the cullin subunit Apc2 in a cryo-electron microscopy model of vertebrate APC/C.
Mol Cell. 20(6):867-79Proximodistal patterning during limb regeneration.
Dev Biol. 279(2):391-401DeltaEF1 is a transcriptional repressor of E-cadherin and regulates epithelial plasticity in breast cancer cells.
Oncogene. 24(14):2375-85Bioinformatics: Mystery, Astrology or Service Technology. Preface for "Discovering Biomolecular Mechanisms with Computational Biology"
Georgetown: Landes Biosciences and Eurekah.com. :1-10Discovering Biomolecular Mechanisms with Computational Biology.
Georgetown: Landes Biosciences and Eurekah.com.Prediction of the Protein Function: Two Basic Concepts and One Practical Recipe. Chapter 3 in
Georgetown: Landes Biosciences and Eurekah.com. :38-53Sequence complexity of proteins and its significance in annotation.
"Bioinformatics" in the Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics (Subramaniam, S., ed.).Asymmetric Rab 11 endosomes regulate delta recycling and specify cell fate in the Drosophila nervous system.
Cell. 122(5):763-73Integration of Ras subeffector signaling in TGF-beta mediated late stage hepatocarcinogenesis.
Carcinogenesis. 26(5):931-42Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer.
Nat Genet. 37(4):391-400The molecular clock mediates leptin-regulated bone formation.
Cell. 122(5):803-15Phosphoproteome and transcriptome analysis of the neuronal response to a CDK5 inhibitor.
Proteomics. 5(5):1299-307Separase is required at multiple pre-anaphase cell cycle stages in human cells.
Cell Cycle. 4(11):1576-84Role of the RB1 family in stabilizing histone methylation at constitutive heterochromatin.
Nat Cell Biol. 7(4):420-8Implications of the serine protease HtrA1 in amyloid precursor protein processing.
Proc Natl Acad Sci U S A. 102(17):6021-6Cell size control: new evidence for a general mechanism.
Cell Cycle. 4(3):418-21Novel genes required for meiotic chromosome segregation are identified by a high-throughput knockout screen in fission yeast.
Curr Biol. 15(18):1663-9SNEV is an evolutionarily conserved splicing factor whose oligomerization is necessary for spliceosome assembly.
Nucleic Acids Res. 33(21):6868-83Molecular machines for protein degradation.
Chembiochem. 6(2):222-56Phosphorylation of ZEN-4/MKLP1 by aurora B regulates completion of cytokinesis.
Curr Biol. 15(8):778-86Molecular processes during fat cell development revealed by gene expression profiling and functional annotation.
Genome Biol. 6(13):R108A REC8-dependent plant Shugoshin is required for maintenance of centromeric cohesion during meiosis and has no mitotic functions.
Curr Biol. 15(10):948-54Translation of stable hepadnaviral mRNA cleavage fragments induced by the action of phosphorothioate-modified antisense oligodeoxynucleotides.
Nucleic Acids Res. 33(1):114-25Dissociation of cohesin from chromosome arms and loss of arm cohesion during early mitosis depends on phosphorylation of SA2.
PLoS Biol. 3(3):e69CD44 is a determinant of inflammatory bone loss.
J Exp Med. 201(6):903-14Identification of cell cycle-dependent phosphorylation sites on the anaphase-promoting complex/cyclosome by mass spectrometry.
Methods Enzymol. 398:231-45Large-scale purification of the vertebrate anaphase-promoting complex/cyclosome.
Methods Enzymol. 398:175-95Canonical Wnt/beta-catenin signaling prevents osteoblasts from differentiating into chondrocytes.
Dev Cell. 8(5):727-38Histone H3 serine 10 phosphorylation by Aurora B causes HP1 dissociation from heterochromatin.
Nature. 438(7071):1176-80Molecular requirements for epithelial-mesenchymal transition during tumor progression.
Curr Opin Cell Biol. 17(5):548-58A topological interaction between cohesin rings and a circular minichromosome.
Cell. 122(6):849-60Afamin is a novel human vitamin E-binding glycoprotein characterization and in vitro expression.
J Proteome Res. 4(3):889-99Chemical cross-linking and high-performance Fourier transform ion cyclotron resonance mass spectrometry for protein interaction analysis: application to a calmodulin/target peptide complex.
Anal Chem. 77(2):495-503Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing.
Genes Dev. 19(4):489-501Aurora A phosphorylation of TACC3/maskin is required for centrosome-dependent microtubule assembly in mitosis.
J Cell Biol. 170(7):1047-55The 1.3 A crystal structure of the flavoprotein YqjM reveals a novel class of Old Yellow Enzymes.
J Biol Chem. 280(30):27904-13Selection and behavior of CD4+ CD25+ T cells in vivo: lessons from T cell receptor transgenic models.
Curr Top Microbiol Immunol. 293:73-87JNK1 is not essential for TNF-mediated joint disease.
Arthritis Res Ther. 7(1):R166-73EZH2 and histone 3 trimethyl lysine 27 associated with Il4 and Il13 gene silencing in Th1 cells.
J Biol Chem. 280(36):31470-7The WD40 propeller domain of Cdh1 functions as a destruction box receptor for APC/C substrates.
Mol Cell. 18(5):543-53Different steroids co-regulate long-term expansion versus terminal differentiation in primary human erythroid progenitors.
Blood. 105(1):85-94TGF-beta-induced apoptosis in endothelial cells mediated by M6P/IGFII-R and mini-plasminogen.
J Cell Sci. 118(Pt 19):4577-86The profile of repeat-associated histone lysine methylation states in the mouse epigenome.
EMBO J. 24(4):800-12Tumor cell invasiveness correlates with changes in integrin expression and localization.
Oncogene. 24(12):2032-41Refinement and prediction of protein prenylation motifs.
Genome Biol. 6(6):R55Shugoshin prevents dissociation of cohesin from centromeres during mitosis in vertebrate cells.
PLoS Biol. 3(3):e86Fos and jun proteins are specifically expressed during differentiation of human keratinocytes.
J Invest Dermatol. 124(1):212-20Proximodistal identity during vertebrate limb regeneration is regulated by Meis homeodomain proteins.
Development. 132(18):4131-42Stat5 tetramer formation is associated with leukemogenesis.
Cancer Cell. 7(1):87-99How might cohesin hold sister chromatids together?
Philos Trans R Soc Lond B Biol Sci. 360(1455):483-96The structure and function of SMC and kleisin complexes.
Annu Rev Biochem. 74:595-648Pivotal role of AtSUVH2 in heterochromatic histone methylation and gene silencing in Arabidopsis.
EMBO J. 24(7):1418-29Proteins with two SUMO-like domains in chromatin-associated complexes: the RENi (Rad60-Esc2-NIP45) family.
BMC Bioinformatics. 6:22PhyloDome--visualization of taxonomic distributions of domains occurring in eukaryote protein sequence sets.
Nucleic Acids Res. 33(Web Server issue):W121-5Species specific membrane anchoring of nyctalopin, a small leucine-rich repeat protein.
Hum Mol Genet. 14(13):1877-87Derivation of 2 categories of plasmacytoid dendritic cells in murine bone marrow.
Blood. 105(11):4407-15HOXB4 enforces equivalent fates of ES-cell-derived and adult hematopoietic cells.
Proc Natl Acad Sci U S A. 102(34):12101-6Distinct functions of junD in cardiac hypertrophy and heart failure.
Genes Dev. 19(2):208-13Locus 'decontraction' and centromeric recruitment contribute to allelic exclusion of the immunoglobulin heavy-chain gene.
Nat Immunol. 6(1):31-41I{kappa}B kinase (IKK){beta}, but not IKK{alpha}, is a critical mediator of osteoclast survival and is required for inflammation-induced bone loss.
J Exp Med. 201(10):1677-87Hedgehog signaling controls dorsoventral patterning, blastema cell proliferation and cartilage induction during axolotl tail regeneration.
Development. 132(14):3243-53Quantitative evaluation of morpholino-mediated protein knockdown of GFP, MSX1, and PAX7 during tail regeneration in Ambystoma mexicanum.
Dev Dyn. 232(1):162-70BCR/ABL promotes dendritic cell-mediated natural killer cell activation.
Cancer Res. 65(14):6409-17Control of Shugoshin function during fission-yeast meiosis.
Curr Biol. 15(24):2263-70TIS7 regulation of the beta-catenin/Tcf-4 target gene osteopontin (OPN) is histone deacetylase-dependent.
J Biol Chem. 280(48):39795-801Fos/AP-1 proteins in bone and the immune system.
Immunol Rev. 208:126-40Introduction: dissection and simplification of chromosome segregation.
Philos Trans R Soc Lond B Biol Sci. 360(1455):481An ECT2-centralspindlin complex regulates the localization and function of RhoA.
J Cell Biol. 170(4):571-82Fragile X protein functions with lgl and the par complex in flies and mice.
Dev Cell. 8(1):43-52Psoriasis-like skin disease and arthritis caused by inducible epidermal deletion of Jun proteins.
Nature. 437(7057):369-75Mammalian inscuteable regulates spindle orientation and cell fate in the developing retina.
Neuron. 48(4):539-45The anaphase promoting complex/cyclosome is recruited to centromeres by the spindle assembly checkpoint.
Nat Cell Biol. 6(9):892-8Tissue-wide expression profiling using cDNA subtraction and microarrays to identify tumor-specific genes.
Cancer Res. 64(3):844-56Phosphorylation by cyclin B-Cdk underlies release of mitotic exit activator Cdc14 from the nucleolus.
Science. 305(5683):516-9FoxO3a regulates erythroid differentiation and induces BTG1, an activator of protein arginine methyl transferase 1.
J Cell Biol. 164(2):175-84Comparative analysis of cytokinesis in budding yeast, fission yeast and animal cells.
Curr Biol. 14(18):R806-18Histone hypomethylation is an indicator of epigenetic plasticity in quiescent lymphocytes.
EMBO J. 23(22):4462-72Dare to be different: asymmetric cell division in Drosophila, C. elegans and vertebrates.
Curr Biol. 14(16):R674-85Systematic Investigation of Non-Nucleoside Inhibitors of HIV-1 Reverse Transcriptase (NNRTIs)
Chemical Monthly . 135(8):1047-1059Tissue-specific expression of cre recombinase from the Pax8 locus.
Genesis. 38(3):105-9A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II.
Mol Cell. 14(5):553-7Transcriptional control of early B cell development.
Annu Rev Immunol. 22:55-79Directed differentiation and mass cultivation of pure erythroid progenitors from mouse embryonic stem cells.
Blood. 104(6):1873-80Tlx3 and Tlx1 are post-mitotic selector genes determining glutamatergic over GABAergic cell fates.
Nat Neurosci. 7(5):510-7TM or not TM: transmembrane protein prediction with low false positive rate using DAS-TMfilter.
Bioinformatics. 20(1):136-7Tension between two kinetochores suffices for their bi-orientation on the mitotic spindle.
Nature. 428(6978):93-7Evidence for a size-sensing mechanism in animal cells.
Nat Cell Biol. 6(9):899-905Su(var) genes regulate the balance between euchromatin and heterochromatin in Drosophila.
Genes Dev. 18(23):2973-83The Fos-related antigen Fra-1 is an activator of bone matrix formation.
EMBO J. 23(14):2789-99beta-Catenin and TGFbeta signalling cooperate to maintain a mesenchymal phenotype after FosER-induced epithelial to mesenchymal transition.
Oncogene. 23(15):2672-2680Prediction of sequence signals for lipid post-translational modifications: insights from case studies.
Proteomics. 4(6):1614-25A sensitive predictor for potential GPI lipid modification sites in fungal protein sequences and its application to genome-wide studies for Aspergillus nidulans, Candida albicans, Neurospora crassa, Saccharomyces cerevisiae and Schizosaccharomyces pombe.
J Mol Biol. 337(2):243-53Structural and functional impairment of an Old Yellow Enzyme homologue upon affinity tag incorporation.
Protein Expr Purif. 36(2):280-91Pax5 induces V-to-DJ rearrangements and locus contraction of the immunoglobulin heavy-chain gene.
Genes Dev. 18(4):411-22Epigenetic regulation of telomere length in mammalian cells by the Suv39h1 and Suv39h2 histone methyltransferases.
Nat Genet. 36(1):94-9Mice with a fra-1 knock-in into the c-fos locus show impaired spatial but regular contextual learning and normal LTP.
Brain Res Mol Brain Res. 130(1-2):16-22Regulation of sister chromatid cohesion between chromosome arms.
Curr Biol. 14(13):1187-93Arthritis induces lymphocytic bone marrow inflammation and endosteal bone formation.
J Bone Miner Res. 19(6):990-8Molecular aspects of epithelial cell plasticity: implications for local tumor invasion and metastasis.
Mutat Res. 566(1):9-20An Ambystoma mexicanum EST sequencing project: analysis of 17,352 expressed sequence tags from embryonic and regenerating blastema cDNA libraries.
Genome Biol. 5(9):R67Structure and stability of cohesin's Smc1-kleisin interaction.
Mol Cell. 15(6):951-64Activated Fps/Fes partially rescues the in vivo developmental potential of Flk1-deficient vascular progenitor cells.
Blood. 103(3):912-20The Drosophila meiotic kleisin C(2)M functions before the meiotic divisions.
Chromosoma. 113(4):177-87Hypoxic induction of Ctgf is directly mediated by Hif-1.
Am J Physiol Renal Physiol. 287(6):F1223-32[Setting the stage for mitosis: kinase regulation of prophase].
Tanpakushitsu Kakusan Koso. 49(8):1183-94Distinct functions of condensin I and II in mitotic chromosome assembly.
J Cell Sci. 117(Pt 26):6435-45Analysis of Notch1 function by in vitro T cell differentiation of Pax5 mutant lymphoid progenitors.
J Immunol. 173(6):3935-44NF-kappaB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression.
J Clin Invest. 114(4):569-81Epithelial-mesenchymal transition: NF-kappaB takes center stage.
Cell Cycle. 3(12):1477-80Sequential roles of Cdc42, Par-6, aPKC, and Lgl in the establishment of epithelial polarity during Drosophila embryogenesis.
Dev Cell. 6(6):845-54Dimethylation of histone H3 lysine 9 is a critical mark for DNA methylation and gene silencing in Arabidopsis thaliana.
Chromosoma. 112(6):308-15Targeted gene knockout reveals a role in meiotic recombination for ZHP-3, a Zip3-related protein in Caenorhabditis elegans.
Mol Cell Biol. 24(18):7998-8006Translational control of putative protooncogene Nm23-M2 by cytokines via phosphoinositide 3-kinase signaling.
J Biol Chem. 279(37):38169-76The AP1 transcription factor Fra2 is required for efficient cartilage development.
Development. 131(22):5717-25Maintenance of cohesin at centromeres after meiosis I in budding yeast requires a kinetochore-associated protein related to MEI-S332.
Curr Biol. 14(7):560-72Spo13 facilitates monopolin recruitment to kinetochores and regulates maintenance of centromeric cohesion during yeast meiosis.
Curr Biol. 14(24):2183-96Mice lacking JunB are osteopenic due to cell-autonomous osteoblast and osteoclast defects.
J Cell Biol. 164(4):613-23Polyomavirus tumorantigens have a profound effect on gene expression in mouse fibroblasts.
Oncogene. 23(27):4707-21A chromosomal memory triggered by Xist regulates histone methylation in X inactivation.
PLoS Biol. 2(7):E171Catecholamine synthesizing enzymes and their modulation by immobilization stress in knockout mice.
Ann N Y Acad Sci. 1018:458-65Crystal structure of the p14/MP1 scaffolding complex: how a twin couple attaches mitogen-activated protein kinase signaling to late endosomes.
Proc Natl Acad Sci U S A. 101(30):10984-9Different EZH2-containing complexes target methylation of histone H1 or nucleosomal histone H3.
Mol Cell. 14(2):183-93Trilogies of histone lysine methylation as epigenetic landmarks of the eukaryotic genome.
Cold Spring Harb Symp Quant Biol. 69:209-18Corecruitment of the Grg4 repressor by PU.1 is critical for Pax5-mediated repression of B-cell-specific genes.
EMBO Rep. 5(3):291-6Dual histone H3 methylation marks at lysines 9 and 27 required for interaction with CHROMOMETHYLASE3.
EMBO J. 23(21):4286-96S. pombe meiotic linear elements contain proteins related to synaptonemal complex components.
J Cell Sci. 117(Pt 15):3343-51FGF signaling is required for initiation of feather placode development.
Development. 131(14):3333-43Enhanced tenascin-C expression and matrix deposition during Ras/TGF-beta-induced progression of mammary tumor cells.
Oncogene. 23(20):3622-33The E2-C vihar is required for the correct spatiotemporal proteolysis of cyclin B and itself undergoes cyclical degradation.
Curr Biol. 14(19):1723-33Nuclear factor of activated T-cells (NFAT) rescues osteoclastogenesis in precursors lacking c-Fos.
J Biol Chem. 279(25):26475-80Myristoylation of viral and bacterial proteins.
Trends Microbiol. 12(4):178-85MYRbase: analysis of genome-wide glycine myristoylation enlarges the functional spectrum of eukaryotic myristoylated proteins.
Genome Biol. 5(3):R21JunD regulates lymphocyte proliferation and T helper cell cytokine expression.
EMBO J. 23(6):1325-35Immortalized p19ARF null hepatocytes restore liver injury and generate hepatic progenitors after transplantation.
Hepatology. 39(3):628-34Cell cycle regulation of central spindle assembly.
Nature. 430(7002):908-13Automated, on-line two-dimensional nano liquid chromatography tandem mass spectrometry for rapid analysis of complex protein digests.
Proteomics. 4(9):2545-57From a single double helix to paired double helices and back.
Philos Trans R Soc Lond B Biol Sci. 359(1441):99-108Hidden localization motifs: naturally occurring peroxisomal targeting signals in non-peroxisomal proteins.
Genome Biol. 5(12):R97SUMO conjugation in plants.
Planta. 220(1):1-8Linking transcriptional mediators via the GACKIX domain super family.
Curr Biol. 14(2):R54-5JunB deficiency leads to a myeloproliferative disorder arising from hematopoietic stem cells.
Cell. 119(3):431-43Generation and characterization of methyl-lysine histone antibodies.
Methods Enzymol. 376:234-54Sister-chromatid cohesion mediated by the alternative RF-CCtf18/Dcc1/Ctf8, the helicase Chl1 and the polymerase-alpha-associated protein Ctf4 is essential for chromatid disjunction during meiosis II.
J Cell Sci. 117(Pt 16):3547-59Two fission yeast homologs of Drosophila Mei-S332 are required for chromosome segregation during meiosis I and II.
Curr Biol. 14(4):287-301The AP-1 transcription factor c-Jun is required for efficient axonal regeneration.
Neuron. 43(1):57-67Requirement of JNK2 for scavenger receptor A-mediated foam cell formation in atherogenesis.
Science. 306(5701):1558-61Is chromatin remodeling required to build sister-chromatid cohesion?
Trends Biochem Sci. 29(8):389-92Normal mineralization and nanostructure of sclerotic bone in mice overexpressing Fra-1.
Bone. 34(5):776-82Loss of vascular endothelial growth factor a activity in murine epidermal keratinocytes delays wound healing and inhibits tumor formation.
Cancer Res. 64(10):3508-16Distinct roles for JNK1 and JNK2 in regulating JNK activity and c-Jun-dependent cell proliferation.
Mol Cell. 15(5):713-25JNK2: a negative regulator of cellular proliferation.
Cell Cycle. 3(12):1520-3Btk is required for an efficient response to erythropoietin and for SCF-controlled protection against TRAIL in erythroid progenitors.
J Exp Med. 199(6):785-95The indexing potential of histone lysine methylation.
Novartis Found Symp. 259:22-37; discussion 37-47, 163-9A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin.
Genes Dev. 18(11):1251-62Human Rif1, ortholog of a yeast telomeric protein, is regulated by ATM and 53BP1 and functions in the S-phase checkpoint.
Genes Dev. 18(17):2108-19Plasticity and reprogramming of differentiated cells in amphibian regeneration: partial purification of a serum factor that triggers cell cycle re-entry in differentiated muscle cells.
Cloning Stem Cells. 6(4):333-44Cdc14 phosphatase induces rDNA condensation and resolves cohesin-independent cohesion during budding yeast anaphase.
Cell. 117(4):471-82Roles of polo-like kinase 1 in the assembly of functional mitotic spindles.
Curr Biol. 14(19):1712-22Epigenetic silencing of the c-fms locus during B-lymphopoiesis occurs in discrete steps and is reversible.
EMBO J. 23(21):4275-85IL-4 confers NK stimulatory capacity to murine dendritic cells: a signaling pathway involving KARAP/DAP12-triggering receptor expressed on myeloid cell 2 molecules.
J Immunol. 172(10):5957-66Glucocorticoid receptor function in hepatocytes is essential to promote postnatal body growth.
Genes Dev. 18(5):492-7Sheet preparations expose the dermal nerve plexus of human skin and render the dermal nerve end organ accessible to extensive analysis.
J Invest Dermatol. 122(1):177-82Muscle regeneration and myogenic differentiation defects in mice lacking TIS7.
Mol Cell Biol. 24(8):3514-25The Btk inhibitor LFM-A13 is a potent inhibitor of Jak2 kinase activity.
Biol Chem. 385(5):409-13APC/C and SCF: controlling each other and the cell cycle.
Curr Biol. 14(18):R787-96Control of erythropoiesis by erythropoietin and stem cell factor: a novel role for Bruton's tyrosine kinase.
Cell Cycle. 3(7):876-9MKK7 couples stress signalling to G2/M cell-cycle progression and cellular senescence.
Nat Cell Biol. 6(3):215-26Inhibitory effect of TIS7 on Sp1-C/EBPalpha transcription factor module activity.
J Mol Biol. 336(3):589-95GermOnline, a cross-species community knowledgebase on germ cell differentiation.
Nucleic Acids Res. 32(Database issue):D560-7Crystal structure of the DegS stress sensor: How a PDZ domain recognizes misfolded protein and activates a protease.
Cell. 117(4):483-94Loss of the anaphase-promoting complex in quiescent cells causes unscheduled hepatocyte proliferation.
Genes Dev. 18(1):88-98Heat shock protein 70 (Hsp70) subtype expression in neuroendocrine tissue and identification of a neuroendocrine tumour-specific Hsp70 truncation.
Endocr Relat Cancer. 11(2):377-89Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase.
Science. 306(5700):1383-6Wnt signalling regulates myogenic differentiation in the developing avian wing.
Development. 130(15):3503-14ATP hydrolysis is required for cohesin's association with chromosomes.
Curr Biol. 13(22):1941-53Impaired intervertebral disc formation in the absence of Jun.
Development. 130(1):103-9The Par complex directs asymmetric cell division by phosphorylating the cytoskeletal protein Lgl.
Nature. 422(6929):326-30Interaction of activator of G-protein signaling 3 (AGS3) with LKB1, a serine/threonine kinase involved in cell polarity and cell cycle progression: phosphorylation of the G-protein regulatory (GPR) motif as a regulatory mechanism for the interaction of GPR motifs with Gi alpha.
J Biol Chem. 278(26):23217-20Mesenchymal patterning by Hoxa2 requires blocking Fgf-dependent activation of Ptx1.
Development. 130(15):3403-14Division of the nucleolus and its release of CDC14 during anaphase of meiosis I depends on separase, SPO12, and SLK19.
Dev Cell. 4(5):727-39Maintenance of stable heterochromatin domains by dynamic HP1 binding.
Science. 299(5607):721-5Polo-like kinase Cdc5 promotes chiasmata formation and cosegregation of sister centromeres at meiosis I.
Nat Cell Biol. 5(5):480-5The MEK-1/ERKs signalling pathway is differentially involved in the self-renewal of early and late avian erythroid progenitor cells.
Oncogene. 22(58):9205-16Centrosome separation and central spindle assembly act in redundant pathways that regulate microtubule density and trigger cleavage furrow formation.
Dev Cell. 4(3):333-44Electroporation as a tool to study in vivo spinal cord regeneration.
Dev Dyn. 226(2):418-25Liver tumor development. c-Jun antagonizes the proapoptotic activity of p53.
Cell. 112(2):181-92AP-1: a double-edged sword in tumorigenesis.
Nat Rev Cancer. 3(11):859-68Enzymes and auxiliary factors for GPI lipid anchor biosynthesis and post-translational transfer to proteins.
Bioessays. 25(4):367-85Glycosylphosphatidylinositol lipid anchoring of plant proteins. Sensitive prediction from sequence- and genome-wide studies for Arabidopsis and rice.
Plant Physiol. 133(4):1691-701Prediction of Post-translational modifications from amino acid sequence: Problems, pitfalls, methodological hints.
Bioinformatics and Genomes: Current Perspectives (Andrade, MM., ed.). :81-105Prediction of lipid posttranslational modifications and localization signals from protein sequences: big-Pi, NMT and PTS1.
Nucleic Acids Res. 31(13):3631-4Measuring Generality of Knowledge-Based Potential Extracted from Protein Structure Sets.
Frontiers in Computational Genomics (Galperin, M., Koonin, E., eds.). :64-93Consequences of the depletion of zygotic and embryonic enhancer of zeste 2 during preimplantation mouse development.
Development. 130(18):4235-48Impaired long-term memory and NR2A-type NMDA receptor-dependent synaptic plasticity in mice lacking c-Fos in the CNS.
J Neurosci. 23(27):9116-22Rhabdomyosarcoma development in mice lacking Trp53 and Fos: tumor suppression by the Fos protooncogene.
Cancer Cell. 4(6):477-82Early mitotic degradation of the homeoprotein HOXC10 is potentially linked to cell cycle progression.
EMBO J. 22(14):3715-24Formation of facultative heterochromatin in the absence of HP1.
EMBO J. 22(20):5540-50Replication-coupled topoisomerase II templates the mitotic chromosome scaffold?
Cell Cycle. 2(3):230-2Molecular shredders: how proteasomes fulfill their role.
Curr Opin Struct Biol. 13(6):665-73Diverse cellular and molecular mechanisms contribute to epithelial plasticity and metastasis.
Nat Rev Mol Cell Biol. 4(8):657-65Building and breaking bridges between sister chromatids.
Bioessays. 25(12):1178-91Cortical and retinal defects caused by dosage-dependent reductions in VEGF-A paracrine signaling.
Dev Biol. 262(2):225-41Wnts in limb bud development.
Wnt Signalling in Development (Kühl, M., ed.). :156-169The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpoint.
J Cell Biol. 161(2):281-94Myeloid lineage switch of Pax5 mutant but not wild-type B cell progenitors by C/EBPalpha and GATA factors.
EMBO J. 22(15):3887-97Genome-wide analysis of gene expression regulated by the HAT cofactor Trrap in conditional knockout cells.
Nucleic Acids Res. 31(23):7011-23Normal incidence of diabetes in NOD mice tolerant to glutamic acid decarboxylase.
J Exp Med. 197(12):1635-44Expression profiling of epithelial plasticity in tumor progression.
Oncogene. 22(46):7155-69Snapshots of the cystine lyase C-DES during catalysis. Studies in solution and in the crystalline state.
J Biol Chem. 278(1):357-65Cooperative signaling between cytokine receptors and the glucocorticoid receptor in the expansion of erythroid progenitors: molecular analysis by expression profiling.
Blood. 102(9):3136-46Mitotic regulation of the human anaphase-promoting complex by phosphorylation.
EMBO J. 22(24):6598-609Evolution of eukaryotic cell cycle regulation: stepwise addition of regulatory kinases and late advent of the CDKs.
Curr Biol. 13(2):173-7An epigenetic road map for histone lysine methylation.
J Cell Sci. 116(Pt 11):2117-24Up-regulation of SLAP in FLI-1-transformed erythroblasts interferes with EpoR signaling.
Blood. 102(13):4555-62Suv39h-mediated histone H3 lysine 9 methylation directs DNA methylation to major satellite repeats at pericentric heterochromatin.
Curr Biol. 13(14):1192-200Lymphatic microvessels in the rat remnant kidney model of renal fibrosis: aminopeptidase p and podoplanin are discriminatory markers for endothelial cells of blood and lymphatic vessels.
J Am Soc Nephrol. 14(8):1981-9The Tudor domain 'Royal Family': Tudor, plant Agenet, Chromo, PWWP and MBT domains.
Trends Biochem Sci. 28(2):69-74Protein prenyltransferases.
Genome Biol. 4(4):212Protein prenyltransferases: anchor size, pseudogenes and parasites.
Biol Chem. 384(7):977-89N-ras mutation in a canine lymphoma: short communication.
Acta Vet Hung. 51(1):91-4K-ras mutations in canine pancreatic cancers.
Vet Rec. 153(3):87-9K-ras protooncogene mutations in feline pancreatic adenocarcinomas.
Vet Rec. 153(15):468-9N-ras mutations in canine malignant melanomas.
Vet J. 165(2):169-71The proto-oncoprotein c-Fos negatively regulates hepatocellular tumorigenesis.
Oncogene. 22(43):6725-38An improved method for tracking and reducing the void volume in nano HPLC-MS with micro trapping columns.
Anal Bioanal Chem. 376(7):946-51Prediction of peroxisomal targeting signal 1 containing proteins from amino acid sequence.
J Mol Biol. 328(3):581-92Motif refinement of the peroxisomal targeting signal 1 and evaluation of taxon-specific differences.
J Mol Biol. 328(3):567-79The STIR-domain superfamily in signal transduction, development and immunity.
Trends Biochem Sci. 28(5):226-9Partitioning and plasticity of repressive histone methylation states in mammalian chromatin.
Mol Cell. 12(6):1577-89Emi1 proteolysis: how SCF(beta-Trcp1) helps to activate the anaphase-promoting complex.
Mol Cell. 11(6):1420-1Un ménage à quatre: the molecular biology of chromosome segregation in meiosis.
Cell. 112(4):423-40Kinetochore recruitment of two nucleolar proteins is required for homolog segregation in meiosis I.
Dev Cell. 4(4):535-48Rheumatoid arthritis therapy after tumor necrosis factor and interleukin-1 blockade.
Arthritis Rheum. 48(12):3308-19The human phosphatidylinositol phosphatase SAC1 interacts with the coatomer I complex.
J Biol Chem. 278(52):52689-99CSC-1: a subunit of the Aurora B kinase complex that binds to the survivin-like protein BIR-1 and the incenp-like protein ICP-1.
J Cell Biol. 161(2):229-36Epigenetic marking correlates with developmental potential in cloned bovine preimplantation embryos.
Curr Biol. 13(13):1116-21Induction of DNA synthesis in primary mouse hepatocytes is associated with nuclear pro-transforming growth factor alpha and erbb-1 and is independent of c-jun.
Carcinogenesis. 24(5):835-41Kleisins: a superfamily of bacterial and eukaryotic SMC protein partners.
Mol Cell. 11(3):571-5Profile of gene expression induced by the tumour promotor TPA in murine epithelial cells.
Int J Cancer. 104(6):699-708Granulocyte-macrophage colony-stimulating factor-based melanoma cell vaccines immunize syngeneic and allogeneic recipients via host dendritic cells.
J Immunol. 171(10):5180-7Flamingo regulates R8 axon-axon and axon-target interactions in the Drosophila visual system.
Curr Biol. 13(10):828-32Mice humanised for the EGF receptor display hypomorphic phenotypes in skin, bone and heart.
Development. 130(19):4515-25Establishment of histone h3 methylation on the inactive X chromosome requires transient recruitment of Eed-Enx1 polycomb group complexes.
Dev Cell. 4(4):481-95Shortstop recruits EB1/APC1 and promotes microtubule assembly at the muscle-tendon junction.
Curr Biol. 13(13):1086-95Conserved and divergent functions of Drosophila atonal, amphibian, and mammalian Ath5 genes.
Evol Dev. 5(5):532-41JunB inhibits proliferation and transformation in B-lymphoid cells.
Blood. 102(12):4159-65Cell differentiation and cell fate during urodele tail and limb regeneration.
Curr Opin Genet Dev. 13(5):497-501The meiosis I-to-meiosis II transition in mouse oocytes requires separase activity.
Curr Biol. 13(20):1797-802Anomalous diffusion on dynamical networks: a model for interacting epithelial cell migration
Physica A: Statistical Mechanics and its Applications. 320:475-484A central role for the JNK pathway in mediating the antagonistic activity of pro-inflammatory cytokines against transforming growth factor-beta-driven SMAD3/4-specific gene expression.
J Biol Chem. 278(3):1585-93TPR subunits of the anaphase-promoting complex mediate binding to the activator protein CDH1.
Curr Biol. 13(17):1459-68Thymic selection revisited: how essential is it?
Immunol Rev. 191:62-78Signalling in osteoclasts and the role of Fos/AP1 proteins.
Ann Rheum Dis. 62 Suppl 2:ii83-5Reannotation of the CELO genome characterizes a set of previously unassigned open reading frames and points to novel modes of host interaction in avian adenoviruses.
BMC Bioinformatics. 4:55JNK phosphorylation relieves HDAC3-dependent suppression of the transcriptional activity of c-Jun.
EMBO J. 22(14):3686-95Activation of ERK1/2 by deltaRaf-1:ER* represses Bim expression independently of the JNK or PI3K pathways.
Oncogene. 22(9):1281-93Induction of short interspersed nuclear repeat-containing transcripts in epithelial cells upon infection with a chicken adenovirus.
J Mol Biol. 328(4):779-90Quantitative measurement of cell migration using time-lapse videomicroscopy and non-linear system analysis.
Histochem Cell Biol. 119(1):15-20Xist RNA associates with chromatin and causes gene silencing.
Non coding RNAs: Molecular biology and molecular (Landes Bioscience) (Barciszewski, J., Erdmann, V., eds.).RNAs templating chromatin structure for dosage compensation in animals.
Bioessays. 25(5):434-42Identification of a subunit of a novel Kleisin-beta/SMC complex as a potential substrate of protein phosphatase 2A.
Curr Biol. 13(23):2058-64c-Jun regulates eyelid closure and skin tumor development through EGFR signaling.
Dev Cell. 4(6):879-89Promoter specificity and biological activity of tethered AP-1 dimers.
Mol Cell Biol. 22(13):4952-64Impaired postnatal hepatocyte proliferation and liver regeneration in mice lacking c-jun in the liver.
EMBO J. 21(7):1782-90Drosophila Aurora-A is required for centrosome maturation and actin-dependent asymmetric protein localization during mitosis.
Curr Biol. 12(8):640-7The endocytic protein alpha-Adaptin is required for numb-mediated asymmetric cell division in Drosophila.
Dev Cell. 3(2):221-31Nephric lineage specification by Pax2 and Pax8.
Genes Dev. 16(22):2958-70Cadherins and the tumour progression: is it all in a switch?
Cancer Lett. 176(2):123-8On filtering false positive transmembrane protein predictions.
Protein Eng. 15(9):745-52JNK1 modulates osteoclastogenesis through both c-Jun phosphorylation-dependent and -independent mechanisms.
J Cell Sci. 115(Pt 22):4317-25Axon guidance: growth cones make an unexpected turn.
Curr Biol. 12(6):R218-20Apoptosis protection by the Epo target Bcl-X(L) allows factor-independent differentiation of primary erythroblasts.
Curr Biol. 12(13):1076-85Ectoderm to mesoderm lineage switching during axolotl tail regeneration.
Science. 298(5600):1993-6Mechanisms of muscle dedifferentiation during regeneration.
Semin Cell Dev Biol. 13(5):353-60FGF signaling regulates expression of Tbx2, Erm, Pea3, and Pax3 in the early nasal region.
Dev Biol. 247(2):237-50Overexpression of vascular endothelial growth factor-A165 enhances tumor angiogenesis but not metastasis during beta-cell carcinogenesis.
Cancer Res. 62(2):603-8Inhibition of proliferation and expression of T1 and cyclin D1 genes by thyroid hormone in mammary epithelial cells.
Mol Carcinog. 34(1):25-34Hepatocytes convert to a fibroblastoid phenotype through the cooperation of TGF-beta1 and Ha-Ras: steps towards invasiveness.
J Cell Sci. 115(Pt 6):1189-202The CeCDC-14 phosphatase is required for cytokinesis in the Caenorhabditis elegans embryo.
J Cell Biol. 158(5):901-14Hormone-sensitive lipase deficiency in mice causes diglyceride accumulation in adipose tissue, muscle, and testis.
J Biol Chem. 277(7):4806-15Molecular architecture of SMC proteins and the yeast cohesin complex.
Mol Cell. 9(4):773-88Human securin proteolysis is controlled by the spindle checkpoint and reveals when the APC/C switches from activation by Cdc20 to Cdh1.
J Cell Biol. 157(7):1125-37Rac function and regulation during Drosophila development.
Nature. 416(6879):438-42Recent advances in cancer research: mouse models of tumorigenesis.
Biochim Biophys Acta. 1602(2):97-113The c-Jun N-terminal kinases in cerebral microglia: immunological functions in the brain.
Biochem Pharmacol. 64(5-6):781-8Differential effects of JNK1 and JNK2 on signal specific induction of apoptosis.
Oncogene. 21(15):2441-5Eco1 is a novel acetyltransferase that can acetylate proteins involved in cohesion.
Curr Biol. 12(4):323-8Ras and TGF[beta] cooperatively regulate epithelial cell plasticity and metastasis: dissection of Ras signaling pathways.
J Cell Biol. 156(2):299-313Oncogenic Ras/Her-2 mediate hyperproliferation of polarized epithelial cells in 3D cultures and rapid tumor growth via the PI3K pathway.
Oncogene. 21(33):5148-59Mechanisms in epithelial plasticity and metastasis: insights from 3D cultures and expression profiling.
J Mammary Gland Biol Neoplasia. 7(4):415-32Molecular biology. An RNA-guided pathway for the epigenome.
Science. 297(5590):2215-8The aurora B kinase AIR-2 regulates kinetochores during mitosis and is required for separation of homologous Chromosomes during meiosis.
Curr Biol. 12(10):798-812A ubiquitin C-terminal hydrolase is required to maintain osmotic balance and execute actin-dependent processes in the early C. elegans embryo.
J Cell Sci. 115(Pt 11):2293-302Reaching a genetic and molecular understanding of skeletal development.
Dev Cell. 2(4):389-406Comm sorts robo to control axon guidance at the Drosophila midline.
Cell. 110(4):415-27Raf-1 antagonizes erythroid differentiation by restraining caspase activation.
J Exp Med. 196(10):1347-53The many faces of histone lysine methylation.
Curr Opin Cell Biol. 14(3):286-98Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression.
EMBO J. 21(11):2672-81Transferrin receptor hyperexpression in primary erythroblasts is lost on transformation by avian erythroblastosis virus.
Blood. 100(1):289-98Mammalian septins nomenclature.
Mol Biol Cell. 13(12):4111-3Higher-order structure in pericentric heterochromatin involves a distinct pattern of histone modification and an RNA component.
Nat Genet. 30(3):329-34N-terminal N-myristoylation of proteins: prediction of substrate proteins from amino acid sequence.
J Mol Biol. 317(4):541-57N-terminal N-myristoylation of proteins: refinement of the sequence motif and its taxon-specific differences.
J Mol Biol. 317(4):523-40Canine N-ras oncogene-mutation in a case of malignant melanoma in the brain.
Folia Veterinaria . 46:161-2Feline tumour suppressor gene p53 - Mutation in a case of bronchial gland carcinoma
Folia Veterinaria . 46:49-51N-ras mutation in a feline lymphoma. Low frequency of N-ras mutations in a series of feline, canine and bovine lymphomas.
Vet J. 163(3):326-8Tumour suppressor gene p53 mutation in a case of haemangiosarcoma of a dog.
Acta Vet Hung. 50(2):157-60GTP binding induces filament assembly of a recombinant septin.
Curr Biol. 12(21):1858-63Histone H3 lysine 9 methylation occurs rapidly at the onset of random X chromosome inactivation.
Curr Biol. 12(3):247-51Reversion of B cell commitment upon loss of Pax5 expression.
Science. 297(5578):110-3Central spindle assembly and cytokinesis require a kinesin-like protein/RhoGAP complex with microtubule bundling activity.
Dev Cell. 2(1):41-54Segregating sister genomes: the molecular biology of chromosome separation.
Science. 297(5581):559-65Rac GTPases control axon growth, guidance and branching.
Nature. 416(6879):442-7A CH domain-containing N terminus in NuMA?
Protein Sci. 11(10):2281-4JunB can substitute for Jun in mouse development and cell proliferation.
Nat Genet. 30(2):158-66Histone H3 lysine 9 methylation is an epigenetic imprint of facultative heterochromatin.
Nat Genet. 30(1):77-80The anaphase-promoting complex: proteolysis in mitosis and beyond.
Mol Cell. 9(5):931-43The activation and maintenance of Pax2 expression at the mid-hindbrain boundary is controlled by separate enhancers.
Development. 129(2):307-18Osteoclasts are essential for TNF-alpha-mediated joint destruction.
J Clin Invest. 110(10):1419-27Transcriptional control of B-cell development.
Curr Opin Immunol. 14(2):216-23Control of pre-BCR signaling by Pax5-dependent activation of the BLNK gene.
Immunity. 17(4):473-85Central role of Drosophila SU(VAR)3-9 in histone H3-K9 methylation and heterochromatic gene silencing.
EMBO J. 21(5):1121-31MLL-ENL cooperates with SCF to transform primary avian multipotent cells.
EMBO J. 21(16):4297-306Selective interactions between vertebrate polycomb homologs and the SUV39H1 histone lysine methyltransferase suggest that histone H3-K9 methylation contributes to chromosomal targeting of Polycomb group proteins.
Mol Cell Biol. 22(15):5539-53High troughput mass-spectrometry for proteomics analysis.
Transkript 2002. 7:37Pax5 promotes B lymphopoiesis and blocks T cell development by repressing Notch1.
Immunity. 17(6):781-93FIP-2, an IkappaB-kinase-gamma-related protein, is associated with the Golgi apparatus and translocates to the marginal band during chicken erythroblast differentiation.
Exp Cell Res. 278(2):133-45The dissociation of cohesin from chromosomes in prophase is regulated by Polo-like kinase.
Mol Cell. 9(3):515-25Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts.
Dev Cell. 3(6):889-901RANKL maintains bone homeostasis through c-Fos-dependent induction of interferon-beta.
Nature. 416(6882):744-9Evidence that the Ipl1-Sli15 (Aurora kinase-INCENP) complex promotes chromosome bi-orientation by altering kinetochore-spindle pole connections.
Cell. 108(3):317-29Localization of the MP1-MAPK scaffold complex to endosomes is mediated by p14 and required for signal transduction.
Dev Cell. 3(6):803-14Dcas is required for importin-alpha3 nuclear export and mechano-sensory organ cell fate specification in Drosophila.
Dev Biol. 244(2):396-406Novel colon cancer cell lines leading to better understanding of the diversity of respective primary cancers.
Oncogene. 21(30):4646-62Distinct involvement of the Jun-N-terminal kinase and NF-kappaB pathways in the repression of the human COL1A2 gene by TNF-alpha.
EMBO Rep. 3(11):1069-74TIS7 interacts with the mammalian SIN3 histone deacetylase complex in epithelial cells.
EMBO J. 21(17):4621-31Conspiracy to disarm APC in interphase.
Nat Cell Biol. 4(5):E119-20Identification of vaccine candidate antigens of Staphylococcus aureus by serological proteome analysis.
Proteomics. 2(5):580-90Regulation of human separase by securin binding and autocleavage.
Curr Biol. 12(16):1368-78Fra-1 substitutes for c-Fos in AP-1-mediated signal transduction in retinal apoptosis.
J Neurochem. 80(6):1089-94Cytoprotective function of keratinocyte growth factor in tumour therapy-induced tissue damage.
Br J Haematol. 116(3):505-10Amino-terminal phosphorylation of c-Jun regulates apoptosis in the retinal ganglion cells by optic nerve transection.
Invest Ophthalmol Vis Sci. 43(5):1631-5Phosphorylation of the cohesin subunit Scc1 by Polo/Cdc5 kinase regulates sister chromatid separation in yeast.
Cell. 105(4):459-72Expression of members of the Fgf family and their receptors during midfacial development.
Mech Dev. 100(2):313-6Ubiquitylation in plants: a post-genomic look at a post-translational modification.
Trends Plant Sci. 6(10):463-70Nuclear receptors in hematopoietic development: cooperation with growth factor receptors in regulation of proliferation and differentiation.
Hematopoiesis. A developmental approach (Zon, L., ed.). :368-390Jun N-terminal kinase 2 modulates thymocyte apoptosis and T cell activation through c-Jun and nuclear factor of activated T cell (NF-AT).
Proc Natl Acad Sci U S A. 98(4):1769-74Genetic mapping with SNP markers in Drosophila.
Nat Genet. 29(4):475-81Keratinocyte-specific onset of serine protease BSSP expression in experimental carcinogenesis.
J Invest Dermatol. 117(3):634-40Inscuteable-dependent apical localization of the microtubule-binding protein Cornetto suggests a role in asymmetric cell division.
J Cell Sci. 114(Pt 20):3655-62Cell adhesion in tumor invasion and metastasis: loss of the glue is not enough.
Biochim Biophys Acta. 1552(1):39-45N-CAM modulates tumour-cell adhesion to matrix by inducing FGF-receptor signalling.
Nat Cell Biol. 3(7):650-7Molecular cloning and characterization of endosialin, a C-type lectin-like cell surface receptor of tumor endothelium.
J Biol Chem. 276(10):7408-14Molecular cloning and characterization of EndoGlyx-1, an EMILIN-like multisubunit glycoprotein of vascular endothelium.
J Biol Chem. 276(51):48588-95Cdk1 triggers association of RNA polymerase to cell cycle promoters only after recruitment of the mediator by SBF.
Mol Cell. 7(6):1213-20Preparation of adenovirus-polylysine-DNA complexes.
Curr Protoc Hum Genet. Chapter 12:Unit 12.3Over-expression of the SUV39H1 histone methyltransferase induces altered proliferation and differentiation in transgenic mice.
Mech Dev. 107(1-2):141-53Making connections. Meeting: axon guidance and neural plasticity.
EMBO Rep. 2(3):182-6MHC class II presentation of endogenously expressed antigens by transfected dendritic cells.
Gene Ther. 8(6):487-93Establishment of normal, terminally differentiating mouse erythroid progenitors: molecular characterization by cDNA arrays.
FASEB J. 15(8):1442-4In vivo imaging indicates muscle fiber dedifferentiation is a major contributor to the regenerating tail blastema.
Dev Biol. 236(1):151-64Post-translational GPI lipid anchor modification of proteins in kingdoms of life: analysis of protein sequence data from complete genomes.
Protein Eng. 14(1):17-25The Brix domain protein family -- a key to the ribosomal biogenesis pathway?
Trends Biochem Sci. 26(6):345-7The transcriptional repressor CDP (Cutl1) is essential for epithelial cell differentiation of the lung and the hair follicle.
Genes Dev. 15(17):2307-19Anaphase-promoting complex/cyclosome-dependent proteolysis of human cyclin A starts at the beginning of mitosis and is not subject to the spindle assembly checkpoint.
J Cell Biol. 153(1):137-48Three-dimensional structure of the anaphase-promoting complex.
Mol Cell. 7(4):907-13Microtubule-independent motility and nuclear targeting of adenoviruses with fluorescently labeled genomes.
J Virol. 75(5):2421-34AP-1 mediated retinal photoreceptor apoptosis is independent of N-terminal phosphorylation of c-Jun.
Cell Death Differ. 8(8):859-67Cohesin cleavage by separase required for anaphase and cytokinesis in human cells.
Science. 293(5533):1320-3E-cadherin
Cancer Research, an Encyclopedic Reference (Schwab, M., ed.). :277-281G1-Cdk activity is required for both proliferation and viability of cytokine-dependent myeloid and erythroid cells.
Oncogene. 20(31):4198-208The role of PAX5 (BSAP) in early and late B-cell development.
Transcription Factors: Normal and Malignant Development of Blood Cells (Ravid, K., Licht, Jd., eds.). :217-228Pax5/BSAP maintains the identity of B cells in late B lymphopoiesis.
Immunity. 14(6):779-90Bazooka and PAR-6 are required with PAR-1 for the maintenance of oocyte fate in Drosophila.
Curr Biol. 11(11):901-6Mammalian sprouty-1 and -2 are membrane-anchored phosphoprotein inhibitors of growth factor signaling in endothelial cells.
J Cell Biol. 152(5):1087-98Securin is required for chromosomal stability in human cells.
Cell. 105(4):445-57Re-SET-ting heterochromatin by histone methyltransferases.
Trends Cell Biol. 11(6):266-73Protective role of Raf-1 in Salmonella-induced macrophage apoptosis.
J Exp Med. 193(3):353-64AP-1 in mouse development and tumorigenesis.
Oncogene. 20(19):2401-12Short- and long-range repulsion by the Drosophila Unc5 netrin receptor.
Neuron. 32(4):605-17The Drosophila nervous system as a model for asymmetric cell division.
Symp Soc Exp Biol. (53):75-89Asymmetric cell division during animal development.
Nat Rev Mol Cell Biol. 2(1):11-20Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins.
Nature. 410(6824):116-20FGF signaling is necessary for the specification of the odontogenic mesenchyme.
Dev Biol. 240(2):548-59Vascular endothelial growth factor-C-mediated lymphangiogenesis promotes tumour metastasis.
EMBO J. 20(4):672-82Cell-autonomous and -nonautonomous functions of LAR in R7 photoreceptor axon targeting.
Neuron. 32(2):225-35Lack of sequence variation in sporadic bovine leucosis in regions of tumour suppressor genes p53 and p16.
J Vet Med A Physiol Pathol Clin Med. 48(6):365-71Embryonic lethality and fetal liver apoptosis in mice lacking the c-raf-1 gene.
EMBO J. 20(8):1952-62Correction of hyperglycemia in diabetic mice transplanted with reversibly immortalized pancreatic beta cells controlled by the tet-on regulatory system.
Cell Transplant. 10(7):645-50Disseminating the genome: joining, resolving, and separating sister chromatids during mitosis and meiosis.
Annu Rev Genet. 35:673-745Splitting the chromosome: cutting the ties that bind sister chromatids.
Novartis Found Symp. 237:113-33; discussion 133-8, 158-63Exciting future planned for birthplace of genetics.
Nature. 413(6856):565Rb targets histone H3 methylation and HP1 to promoters.
Nature. 412(6846):561-5Can molecular mechanisms of biological processes be extracted from expression profiles? Case study: endothelial contribution to tumor-induced angiogenesis.
Bioessays. 23(12):1159-75Pax5 determines the identity of B cells from the beginning to the end of B-lymphopoiesis.
Int Rev Immunol. 20(1):65-82The polycomb-group gene Ezh2 is required for early mouse development.
Mol Cell Biol. 21(13):4330-6DNA/polyethylenimine transfection particles: influence of ligands, polymer size, and PEGylation on internalization and gene expression.
AAPS PharmSci. 3(3):E21A Caenorhabditis elegans cohesion protein with functions in meiotic chromosome pairing and disjunction.
Genes Dev. 15(11):1349-60Chronic myeloid leukemia with increased granulocyte progenitors in mice lacking junB expression in the myeloid lineage.
Cell. 104(1):21-32Modes of spindle pole body inheritance and segregation of the Bfa1p-Bub2p checkpoint protein complex.
EMBO J. 20(22):6359-70Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability.
Cell. 107(3):323-37DmPAR-6 directs epithelial polarity and asymmetric cell division of neuroblasts in Drosophila.
Nat Cell Biol. 3(1):43-9Translation control: bridging the gap between genomics and proteomics?
Trends Biochem Sci. 26(4):225-9A screen for genes required for meiosis and spore formation based on whole-genome expression.
Curr Biol. 11(13):1001-9Degradation of a cohesin subunit by the N-end rule pathway is essential for chromosome stability.
Nature. 410(6831):955-9Mammary gland development and lactation are controlled by different glucocorticoid receptor activities.
Eur J Endocrinol. 145(4):519-27Emi1 is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex.
Cell. 105(5):645-55c-Jun NH2-terminal kinase (JNK)1 and JNK2 have similar and stage-dependent roles in regulating T cell apoptosis and proliferation.
J Exp Med. 193(3):317-28Protein localization during asymmetric cell division.
Exp Cell Res. 271(1):66-74Heterotrimeric G proteins direct two modes of asymmetric cell division in the Drosophila nervous system.
Cell. 107(2):183-94Separase is required for chromosome segregation during meiosis I in Caenorhabditis elegans.
Curr Biol. 11(23):1825-35Sister chromatid cohesion is required for postreplicative double-strand break repair in Saccharomyces cerevisiae.
Curr Biol. 11(12):991-5Scc1/Rad21/Mcd1 is required for sister chromatid cohesion and kinetochore function in vertebrate cells.
Dev Cell. 1(6):759-70Overexpression of Pax5 is not sufficient for neoplastic transformation of mouse neuroectoderm.
Int J Cancer. 93(4):459-67E-cadherin regulates cell growth by modulating proliferation-dependent beta-catenin transcriptional activity.
J Cell Biol. 154(6):1185-96Listeria monocytogenes modulates macrophage cytokine responses through STAT serine phosphorylation and the induction of suppressor of cytokine signaling 3.
J Immunol. 166(1):466-72Differential utilization and localization of ErbB receptor tyrosine kinases in skin compared to normal and malignant keratinocytes.
Neoplasia. 3(4):339-50A conserved cyclin-binding domain determines functional interplay between anaphase-promoting complex-Cdh1 and cyclin A-Cdk2 during cell cycle progression.
Mol Cell Biol. 21(11):3692-703Defining CAR as a cellular receptor for the avian adenovirus CELO using a genetic analysis of the two viral fibre proteins.
J Gen Virol. 82(Pt 6):1465-1472The Drosophila tuberous sclerosis complex gene homologs restrict cell growth and cell proliferation.
Cell. 105(3):345-55Expression of collagenase-3 (MMP-13) in c-fos-induced osteosarcomas and chondrosarcomas is restricted to a subset of cells of the osteo-/chondrogenic lineage.
Differentiation. 69(1):49-57Perturbation of the tight junction permeability barrier by occludin loop peptides activates beta-catenin/TCF/LEF-mediated transcription.
EMBO Rep. 2(4):306-12Cell cycle: Waiters serving the Destruction machinery.
Curr Biol. 11(20):R834-7Leukemic transformation of normal murine erythroid progenitors: v- and c-ErbB act through signaling pathways activated by the EpoR and c-Kit in stress erythropoiesis.
Oncogene. 20(28):3651-64Genetic control of skeletal development.
Curr Opin Genet Dev. 11(5):527-32Crystal structure of the APC10/DOC1 subunit of the human anaphase-promoting complex.
Nat Struct Biol. 8(9):784-8Taxonomy workbench.
Bioinformatics. 17(12):1179-82A novel 14-kilodalton protein interacts with the mitogen-activated protein kinase scaffold mp1 on a late endosomal/lysosomal compartment.
J Cell Biol. 152(4):765-76Non-imprinted Igf2r expression decreases growth and rescues the Tme mutation in mice.
Development. 128(10):1881-7Distinct regulators control the expression of the mid-hindbrain organizer signal FGF8.
Nat Neurosci. 4(12):1175-81Mitotic phosphorylation of SUV39H1, a novel component of active centromeres, coincides with transient accumulation at mammalian centromeres.
J Cell Sci. 113 ( Pt 5):817-29Oncogenic transformation by ras and fos is mediated by c-Jun N-terminal phosphorylation.
Oncogene. 19(22):2657-63Cloning and characterization of the murine glucosamine-6-phosphate acetyltransferase EMeg32. Differential expression and intracellular membrane association.
J Biol Chem. 275(17):12821-32Functional equivalence of the transcription factors Pax2 and Pax5 in mouse development.
Development. 127(17):3703-13Cell cycle dependence of gene transfer by lipoplex, polyplex and recombinant adenovirus.
Gene Ther. 7(5):401-7Disjunction of homologous chromosomes in meiosis I depends on proteolytic cleavage of the meiotic cohesin Rec8 by separin.
Cell. 103(3):387-98Lineage commitment in lymphopoiesis.
Curr Opin Immunol. 12(2):151-8Molecular mechanisms of tumor angiogenesis and tumor progression.
J Neurooncol. 50(1-2):63-70Cohesin's binding to chromosomes depends on a separate complex consisting of Scc2 and Scc4 proteins.
Mol Cell. 5(2):243-54Recent advances in research on multistage tumorigenesis.
Br J Cancer. 83(1):1-5Fibroblast growth factors are required for efficient tumor angiogenesis.
Cancer Res. 60(24):7163-9Characterisation of the rubber elongation factor from ammoniated latex by electrophoresis and mass spectrometry.
J Chromatogr A. 890(1):145-58Transcriptional repression by Pax5 (BSAP) through interaction with corepressors of the Groucho family.
EMBO J. 19(10):2292-303Epithelial mesenchymal transition by c-Fos estrogen receptor activation involves nuclear translocation of beta-catenin and upregulation of beta-catenin/lymphoid enhancer binding factor-1 transcriptional activity.
J Cell Biol. 148(1):173-88Automated annotation of GPI anchor sites: case study C. elegans.
Trends Biochem Sci. 25(7):340-1Fra-1 replaces c-Fos-dependent functions in mice.
Genes Dev. 14(21):2695-700The recycling endosome of Madin-Darby canine kidney cells is a mildly acidic compartment rich in raft components.
Mol Biol Cell. 11(8):2775-91Erythroid cell development and leukemic transformation: interplay between signal transduction, cell cycle control and oncogenes.
Pathol Biol (Paris). 48(3):211-26Cullins and cell cycle control.
Protoplasma. 211:20-28Activation of heat-shock response by an adenovirus is essential for virus replication.
Nature. 407(6801):207-11The RING-H2 finger protein APC11 and the E2 enzyme UBC4 are sufficient to ubiquitinate substrates of the anaphase-promoting complex.
Proc Natl Acad Sci U S A. 97(16):8973-8Altered subcellular distribution of cadherin-5 in endothelial cells caused by the serum of pre-eclamptic patients.
Mol Hum Reprod. 6(11):1027-32Conditional inactivation of VEGF-A in areas of collagen2a1 expression results in embryonic lethality in the heterozygous state.
Development. 127(7):1445-53Transgenic activation of Ras in neurons promotes hypertrophy and protects from lesion-induced degeneration.
J Cell Biol. 151(7):1537-48The puzzle of size control in organisms.
B.I.F. Futura . 15:81-90Both calmodulin and the unconventional myosin Myr4 regulate membrane trafficking along the recycling pathway of MDCK cells.
Traffic. 1(6):494-503CYK-4: A Rho family gtpase activating protein (GAP) required for central spindle formation and cytokinesis.
J Cell Biol. 149(7):1391-404Increased bone formation and osteosclerosis in mice overexpressing the transcription factor Fra-1.
Nat Med. 6(9):980-4Incenp and an aurora-like kinase form a complex essential for chromosome segregation and efficient completion of cytokinesis.
Curr Biol. 10(19):1172-81Antiapoptotic activity of Stat5 required during terminal stages of myeloid differentiation.
Genes Dev. 14(2):232-44Epithelial polarity: the ins and outs of the fly epidermis.
Curr Biol. 10(21):R791-4c-Jun-dependent CD95-L expression is a rate-limiting step in the induction of apoptosis by alkylating agents.
Mol Cell Biol. 20(2):575-82Mitotic regulation of the APC activator proteins CDC20 and CDH1.
Mol Biol Cell. 11(5):1555-69Osteoclast lineage commitment of bone marrow precursors through expression of membrane-bound TRANCE.
Bone. 27(1):29-40Raf induces TGFbeta production while blocking its apoptotic but not invasive responses: a mechanism leading to increased malignancy in epithelial cells.
Genes Dev. 14(20):2610-22Fosl1 is a transcriptional target of c-Fos during osteoclast differentiation.
Nat Genet. 24(2):184-7Presence of p53 mutations in feline neoplasms.
Res Vet Sci. 68(1):63-70Comparative studies in the promoter and exon 1 regions of tumour suppressor p53 in several mammalian species: absence of mutations in a panel of spontaneous domestic animal tumours.
J Vet Med A Physiol Pathol Clin Med. 47(10):593-7Activation of the beta globin locus by transcription factors and chromatin modifiers.
EMBO J. 19(18):4986-96Structure-function analysis of SUV39H1 reveals a dominant role in heterochromatin organization, chromosome segregation, and mitotic progression.
Mol Cell Biol. 20(10):3728-41Isolation of translationally controlled mRNAs by differential screening.
FASEB J. 14(11):1641-52Regulation of ferritin mRNA translation in primary erythroblasts: exogenous c-Kit plus EpoR signaling mimics v-ErbA oncoprotein activity.
Biochem Biophys Res Commun. 275(2):292-4Splitting the chromosome: cutting the ties that bind sister chromatids.
Science. 288(5470):1379-85Analysis of Drosophila photoreceptor axon guidance in eye-specific mosaics.
Development. 127(4):851-60Trio combines with dock to regulate Pak activity during photoreceptor axon pathfinding in Drosophila.
Cell. 101(3):283-94Isolation and characterization of Suv39h2, a second histone H3 methyltransferase gene that displays testis-specific expression.
Mol Cell Biol. 20(24):9423-33A versatile assay to study cellular uptake of gene transfer complexes by flow cytometry.
Biochim Biophys Acta. 1474(2):237-43Hyaluronic acid (HA) binding to CD44 activates Rac1 and induces lamellipodia outgrowth.
J Cell Biol. 148(6):1159-64Pds5 cooperates with cohesin in maintaining sister chromatid cohesion.
Curr Biol. 10(24):1557-64JunB suppresses cell proliferation by transcriptional activation of p16(INK4a) expression.
EMBO J. 19(12):2969-79Cell cycle- and cell growth-regulated proteolysis of mammalian CDC6 is dependent on APC-CDH1.
Genes Dev. 14(18):2330-43TGF-beta inhibits p70 S6 kinase via protein phosphatase 2A to induce G(1) arrest.
Genes Dev. 14(24):3093-101Pax2 and homeodomain proteins cooperatively regulate a 435 bp enhancer of the mouse Pax5 gene at the midbrain-hindbrain boundary.
Development. 127(5):1017-28Crossing the midline: roles and regulation of Robo receptors.
Neuron. 28(3):767-77Selecting a longitudinal pathway: Robo receptors specify the lateral position of axons in the Drosophila CNS.
Cell. 103(7):1033-45Regulation of chromatin structure by site-specific histone H3 methyltransferases.
Nature. 406(6796):593-9A syndrome involving intrauterine growth retardation, microcephaly, cerebellar hypoplasia, B lymphocyte deficiency, and progressive pancytopenia.
Pediatrics. 105(3):E39Fidelity and infidelity in commitment to B-lymphocyte lineage development.
Immunol Rev. 175:104-11Destruction of the securin Pds1p occurs at the onset of anaphase during both meiotic divisions in yeast.
Chromosoma. 109(1-2):27-34A protein complex containing Inscuteable and the Galpha-binding protein Pins orients asymmetric cell divisions in Drosophila.
Curr Biol. 10(7):353-62Placental vascularisation requires the AP-1 component fra1.
Development. 127(22):4937-48brakeless is required for lamina targeting of R1-R6 axons in the Drosophila visual system.
Development. 127(11):2291-301The mammalian UV response: c-Jun induction is required for exit from p53-imposed growth arrest.
Cell. 103(6):897-907The EGF receptor provides an essential survival signal for SOS-dependent skin tumor development.
Cell. 102(2):211-20Nonperiodic activity of the human anaphase-promoting complex-Cdh1 ubiquitin ligase results in continuous DNA synthesis uncoupled from mitosis.
Mol Cell Biol. 20(20):7613-23Characterization of vertebrate cohesin complexes and their regulation in prophase.
J Cell Biol. 151(4):749-62Intramedullary and extramedullary B lymphopoiesis in osteopetrotic mice.
Blood. 95(11):3363-70Cohesin ensures bipolar attachment of microtubules to sister centromeres and resists their precocious separation.
Nat Cell Biol. 2(8):492-9Characterization of fission yeast cohesin: essential anaphase proteolysis of Rad21 phosphorylated in the S phase.
Genes Dev. 14(21):2757-70Functional genomics identifies monopolin: a kinetochore protein required for segregation of homologs during meiosis i.
Cell. 103(7):1155-68Cleavage of cohesin by the CD clan protease separin triggers anaphase in yeast.
Cell. 103(3):375-86Targeting of N-CoR and histone deacetylase 3 by the oncoprotein v-erbA yields a chromatin infrastructure-dependent transcriptional repression pathway.
EMBO J. 19(15):4074-90Generation of mononucleate cells from post-mitotic myotubes proceeds in the absence of cell cycle progression.
Differentiation. 66(4-5):239-46Protein kinase C alpha controls erythropoietin receptor signaling.
J Biol Chem. 275(44):34719-27Two distinct pathways remove mammalian cohesin from chromosome arms in prophase and from centromeres in anaphase.
Cell. 103(3):399-410JunD protects cells from p53-dependent senescence and apoptosis.
Mol Cell. 6(5):1109-19Functional mammalian homologues of the Drosophila PEV-modifier Su(var)3-9 encode centromere-associated proteins which complex with the heterochromatin component M31.
EMBO J. 18(7):1923-38Sister chromatid separation and chromosome re-duplication are regulated by different mechanisms in response to spindle damage.
EMBO J. 18(10):2707-21Variations of p53 in cultured fibroblasts of patients with lung cancer who have a presumed genetic predisposition.
Am J Clin Oncol. 22(3):278-82The glucocorticoid receptor is required for stress erythropoiesis.
Genes Dev. 13(22):2996-3002A putative role for c-Fos in the pathophysiology of Paget's disease.
J Bone Miner Res. 14 Suppl 2:21-8Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation.
Nat Genet. 21(3):326-9Transient transfection of mammary epithelial cells with a PEI/DNA/adenovirus system.
Biol Chem. 380(2):269-73Mice lacking the poly(ADP-ribose) polymerase gene are resistant to pancreatic beta-cell destruction and diabetes development induced by streptozocin.
Nat Med. 5(3):314-9The IGF/IGF-1 receptor signaling pathway as a potential target for cancer therapy.
Drug Resist Updat. 2(1):3-8An insulin-like growth factor-mediated, phosphatidylinositol 3' kinase-independent survival signaling pathway in beta tumor cells.
Cancer Res. 59(16):3923-6The role of the cell-adhesion molecule E-cadherin as a tumour-suppressor gene.
Trends Biochem Sci. 24(2):73-6Ordered recruitment of transcription and chromatin remodeling factors to a cell cycle- and developmentally regulated promoter.
Cell. 97(3):299-311Receptor-mediated gene delivery strategies.
The Development of Human Gene Therapy (ed. Friedmann, T.). :261-77twin of eyeless, a second Pax-6 gene of Drosophila, acts upstream of eyeless in the control of eye development.
Mol Cell. 3(3):297-307Role of the ATFa/JNK2 complex in Jun activation.
Oncogene. 18(23):3491-500Mannose polyethylenimine conjugates for targeted DNA delivery into dendritic cells.
J Biol Chem. 274(27):19087-94Efficient gene delivery into human dendritic cells by adenovirus polyethylenimine and mannose polyethylenimine transfection.
Hum Gene Ther. 10(5):775-86The partial homeodomain of the transcription factor Pax-5 (BSAP) is an interaction motif for the retinoblastoma and TATA-binding proteins.
Cancer Res. 59(7 Suppl):1716s-1724s; discussion 1724s-1725sFunctions of c-Jun in liver and heart development.
J Cell Biol. 145(5):1049-61Prediction of potential GPI-modification sites in proprotein sequences.
J Mol Biol. 292(3):741-58Hydrophobic regions on protein surfaces.
Perspectives in Drug Discovery and Design. v. 17(N1):27-42Neural cell adhesion molecule (N-CAM) is required for cell type segregation and normal ultrastructure in pancreatic islets.
J Cell Biol. 144(2):325-37Endocytic organelles: Methods for preparation.
Encyclopedia of Life Sciences (www.els.net).Loss of epithelial polarity is accompanied by differential association of proteins with intracellular membranes.
Electrophoresis. 20(2):331-43Identification of syntenin as a protein of the apical early endocytic compartment in Madin-Darby canine kidney cells.
J Biol Chem. 274(37):26233-9The MYC dualism in growth and death.
Mutat Res. 437(3):205-17TGF-beta cooperates with TGF-alpha to induce the self-renewal of normal erythrocytic progenitors: evidence for an autocrine mechanism.
EMBO J. 18(10):2764-81Expression of the CDH1-associated form of the anaphase-promoting complex in postmitotic neurons.
Proc Natl Acad Sci U S A. 96(20):11317-22Chromosome segregation: Samurai separation of Siamese sisters.
Curr Biol. 9(14):R531-4ASH1 mRNA localization in yeast involves multiple secondary structural elements and Ash1 protein translation.
Curr Biol. 9(6):337-40Characterization of the DOC1/APC10 subunit of the yeast and the human anaphase-promoting complex.
J Biol Chem. 274(20):14500-7An unexpected role for p53 in augmenting SV40 large T antigen-mediated tumorigenesis.
Biol Chem. 380(2):203-11The use of in vitro expanded erythroid cells in a model system for the isolation of fetal cells from maternal blood.
Prenat Diagn. 19(4):323-9Depletion of syntaxins in the early Caenorhabditis elegans embryo reveals a role for membrane fusion events in cytokinesis.
Curr Biol. 9(14):738-45[Loss of junB expression causes a myeloproliferative syndrome resembling chronic myeloid leukemia].
Verh Dtsch Ges Pathol. 83:216-7GRC5 and NMD3 function in translational control of gene expression and interact genetically.
Curr Genet. 34(6):419-29A central role for cohesins in sister chromatid cohesion, formation of axial elements, and recombination during yeast meiosis.
Cell. 98(1):91-103Deletion analysis of the Drosophila Inscuteable protein reveals domains for cortical localization and asymmetric localization.
Curr Biol. 9(3):155-8Epitope tagging of yeast genes using a PCR-based strategy: more tags and improved practical routines.
Yeast. 15(10B):963-72T cell activation-associated epitopes of CD147 in regulation of the T cell response, and their definition by antibody affinity and antigen density.
Int Immunol. 11(5):777-86Molecular cloning and expression of the human and mouse homologues of the Drosophila dachshund gene.
Dev Genes Evol. 209(9):537-45The murine polycomb-group genes Ezh1 and Ezh2 map close to Hox gene clusters on mouse chromosomes 11 and 6.
Mamm Genome. 10(3):311-4Molecular calculations on the conformation of the HIV-1 reverse transcriptase inhibitor 1-[(2-Hydroxyethoxy)methyl]-6-[phenylthio]-thymine [HEPT].
Monatshefte für Chemie. 130:1347-63Conformational study of the HIV-1 reverse transcriptase inhibitor 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine (HEPT).
Biol Chem. 380(2):265-7Characterization of CELO virus proteins that modulate the pRb/E2F pathway.
J Virol. 73(8):6517-25Self-renewal, maturation, and differentiation of the rat myelomonocytic hematopoietic stem cell.
FASEB J. 13(2):263-72Accumulation of cyclin B1 requires E2F and cyclin-A-dependent rearrangement of the anaphase-promoting complex.
Nature. 401(6755):815-8Function of Fos proteins in bone cell differentiation.
Bone. 25(1):141Mutational analysis of the avian adenovirus CELO, which provides a basis for gene delivery vectors.
J Virol. 73(2):1399-410Impaired ferritin mRNA translation in primary erythroid progenitors: shift to iron-dependent regulation by the v-ErbA oncoprotein.
Blood. 94(12):4321-32Post-transcriptional control via iron-responsive elements: the impact of aberrations in hereditary disease.
Mutat Res. 437(3):219-30Vertebrate Sprouty genes are induced by FGF signaling and can cause chondrodysplasia when overexpressed.
Development. 126(20):4465-75Formation of transformed endothelial cells in the absence of VEGFR-2/Flk-1 by Polyoma middle T oncogene.
Oncogene. 18(29):4200-10The IMP and European molecular biology: moving the centre eastwards. Institute of Molecular Pathology.
Biol Chem. 380(2):113-4Finishing the cell cycle.
J Theor Biol. 199(2):223-33Monoallelic expression of Pax5: a paradigm for the haploinsufficiency of mammalian Pax genes?
Biol Chem. 380(6):601-11Commitment to the B-lymphoid lineage depends on the transcription factor Pax5.
Nature. 401(6753):556-62The molecular basis of B-cell lineage commitment.
Cold Spring Harb Symp Quant Biol. 64:51-9Independent regulation of the two Pax5 alleles during B-cell development.
Nat Genet. 21(4):390-5Analysis of CD44-containing lipid rafts: Recruitment of annexin II and stabilization by the actin cytoskeleton.
J Cell Biol. 146(4):843-54Fra-1 potentiates osteoclastic differentiation in osteoclast-macrophage precursor cell lines.
J Cell Physiol. 179(2):170-8Subcellular fractionation, electromigration analysis and mapping of organelles.
J Chromatogr B Biomed Sci Appl. 722(1-2):89-102FLI-1 inhibits differentiation and induces proliferation of primary erythroblasts.
Oncogene. 18(8):1597-608Reduced expression of neural cell adhesion molecule induces metastatic dissemination of pancreatic beta tumor cells.
Nat Med. 5(3):286-91Subunits and substrates of the anaphase-promoting complex.
Exp Cell Res. 248(2):339-49Differentiation, dedifferentiation, and redifferentiation of B-lineage lymphocytes: roles of the surrogate light chain and the Pax5 gene.
Cold Spring Harb Symp Quant Biol. 64:21-5Long-term in vivo reconstitution of T-cell development by Pax5-deficient B-cell progenitors.
Nature. 401(6753):603-6JNK2 is required for efficient T-cell activation and apoptosis but not for normal lymphocyte development.
Curr Biol. 9(3):116-25Defective neural tube morphogenesis and altered apoptosis in the absence of both JNK1 and JNK2.
Mech Dev. 89(1-2):115-24Bazooka recruits Inscuteable to orient asymmetric cell divisions in Drosophila neuroblasts.
Nature. 402(6761):548-51JunB is essential for mammalian placentation.
EMBO J. 18(4):934-48Control of cell cycle progression by c-Jun is p53 dependent.
Genes Dev. 13(5):607-19Immunotherapy of metastatic malignant melanoma by a vaccine consisting of autologous interleukin 2-transfected cancer cells: outcome of a phase I study.
Hum Gene Ther. 10(6):983-93Pax2/5 and Pax6 subdivide the early neural tube into three domains.
Mech Dev. 82(1-2):29-39Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34.
Genes Dev. 13(12):1614-26APC(Cdc20) promotes exit from mitosis by destroying the anaphase inhibitor Pds1 and cyclin Clb5.
Nature. 402(6758):203-7Lipopolysaccharide induces in macrophages the synthesis of the suppressor of cytokine signaling 3 and suppresses signal transduction in response to the activating factor IFN-gamma.
J Immunol. 163(5):2640-7Thrombin regulates S-phase re-entry by cultured newt myotubes.
Curr Biol. 9(15):792-9Identification of cohesin association sites at centromeres and along chromosome arms.
Cell. 98(6):847-58Yeast cohesin complex requires a conserved protein, Eco1p(Ctf7), to establish cohesion between sister chromatids during DNA replication.
Genes Dev. 13(3):320-33Distinct neural stem cells proliferate in response to EGF and FGF in the developing mouse telencephalon.
Dev Biol. 208(1):166-88Sister-chromatid separation at anaphase onset is promoted by cleavage of the cohesin subunit Scc1.
Nature. 400(6739):37-42Fibroblast growth factors in tumor progression and angiogenesis.
Antiangiogenic Agents in Cancer Therapy (ed. Teicher, BA.). :83-118The glucocorticoid receptor cooperates with the erythropoietin receptor and c-Kit to enhance and sustain proliferation of erythroid progenitors in vitro.
Blood. 94(2):550-9Genetically modified mice as tolls for cancer research.
Development-Genetics, Epigenetics and Environmental Regulation (eds. Russo, D., Cove, L., Edgar, R., Jaenisch, Salamini, F. . :471-85A novel way to induce erythroid progenitor self renewal: cooperation of c-Kit with the erythropoietin receptor.
Biol Chem. 380(2):187-202Whose end is destruction: cell division and the anaphase-promoting complex.
Genes Dev. 13(16):2039-58The thyroid hormone receptor functions as a ligand-operated developmental switch between proliferation and differentiation of erythroid progenitors.
EMBO J. 17(15):4291-303recessive spotting: a linked locus that interacts with W/Kit but is not allelic.
Genes Cells. 3(4):235-44Chemically defined, cell-free cancer vaccines: use of tumor antigen-derived peptides or polyepitope proteins for vaccination.
Gene Therapy and Molecular Biology. 1:309-21Role of the transcription factor BSAP [Pax-5] in B-cell development.
Molecular Biology of B-Cell and T-Cell Development (eds. Monroe, JG., Rothenberg, EV.). :83-110The implications of angiogenesis on tumor invasiveness.
Angiogenesis. 2(1):21-3Leukemic transformation by the v-ErbA oncoprotein entails constitutive binding to and repression of an erythroid enhancer in vivo.
EMBO J. 17(24):7382-94An ESP1/PDS1 complex regulates loss of sister chromatid cohesion at the metaphase to anaphase transition in yeast.
Cell. 93(6):1067-76Transfection complexes generated with adenovirus and polyethylenimine-condensed DNA.
Methods in Molecular Biology; Adenovirus Methods and Protocols (ed. Wold, WSM.). :295-307Transformation of hematopoietic cells by the Ski oncoprotein involves repression of retinoic acid receptor signaling.
Proc Natl Acad Sci U S A. 95(19):11187-92Gene-modified dendritic cells by receptor-mediated transfection.
Adv Exp Med Biol. 451:449-55Three-dimensional organotypic growth of epithelial cells in reconstituted extracellular matrix.
Cell Biology - A Laboratory Handbook (ed. Celis, JE.). 1:107-12Cell multiplication - editorial overview.
Current Opinion in Cell Biology . 10:739-41Preparation and purification of post-golgi vesicles from perforated Madin-Darby Canine Kidney Cells.
Cell Biology - A Laboratory Handbook (ed. Celis, JE.). 1:56-62SET domain proteins modulate chromatin domains in eu- and heterochromatin.
Cell Mol Life Sci. 54(1):80-93Activation of the human anaphase-promoting complex by proteins of the CDC20/Fizzy family.
Curr Biol. 8(22):1207-10Impairment of survival factor function potentiates chemotherapy-induced apoptosis in tumor cells.
Cancer Res. 58(4):801-7A multithreaded Java framework for solving linear elliptic partial differential equations in 3D.
Lecture Notes in Computer Science. 1343:121-8PAX8 mutations associated with congenital hypothyroidism caused by thyroid dysgenesis.
Nat Genet. 19(1):83-6Novel p53 tumour suppressor mutations in cases of spindle cell sarcoma, pleomorphic sarcoma and fibrosarcoma in cats.
Vet Res Commun. 22(4):249-55Deregulated PAX-5 transcription from a translocated IgH promoter in marginal zone lymphoma.
Blood. 92(10):3865-78Loss- and gain-of-function mutations reveal an important role of BSAP (Pax-5) at the start and end of B cell differentiation.
Semin Immunol. 10(2):133-42Neisseria gonorrhoeae porin modulates phagosome maturation.
J Biol Chem. 273(52):35332-8Model scenarios for evolution of the eukaryotic cell cycle.
Philos Trans R Soc Lond B Biol Sci. 353(1378):2063-76Identification of BSAP (Pax-5) target genes in early B-cell development by loss- and gain-of-function experiments.
EMBO J. 17(8):2319-33TGFbeta signaling is necessary for carcinoma cell invasiveness and metastasis.
Curr Biol. 8(23):1243-52The size of DNA/transferrin-PEI complexes is an important factor for gene expression in cultured cells.
Gene Ther. 5(10):1425-33Embryonic overexpression of the c-Fos protooncogene. A murine stem cell chimera applicable to the study of fibrodysplasia ossificans progressiva in humans.
Clin Orthop Relat Res. (346):81-94Assignment of the gene encoding the core promoter element binding protein (COPEB) to human chromosome 10p15 by somatic hybrid analysis and fluorescence in situ hybridization.
Genomics. 48(1):143-4Molecular cloning and expression analysis of five novel genes in chromosome 1p36.
Genomics. 50(2):187-98A causal role for E-cadherin in the transition from adenoma to carcinoma.
Nature. 392(6672):190-3SCF and APC: the Yin and Yang of cell cycle regulated proteolysis.
Curr Opin Cell Biol. 10(6):759-68Cell cycle control by ubiquitin-dependent proteolysis.
Ubiquitin and the biology of the cell (eds. Peters, JM., Harris, JR., Finley, D.) . :345-87Characterization of three novel members of the zebrafish Pax2/5/8 family: dependency of Pax5 and Pax8 expression on the Pax2.1 (noi) function.
Development. 125(16):3063-74The tumor-suppressor function of E-cadherin.
Am J Hum Genet. 63(6):1588-93The Polo-like kinase Cdc5p and the WD-repeat protein Cdc20p/fizzy are regulators and substrates of the anaphase promoting complex in Saccharomyces cerevisiae.
EMBO J. 17(5):1336-49A strain-independent postnatal neurodegeneration in mice lacking the EGF receptor.
EMBO J. 17(3):719-31A target of thrombin activation promotes cell cycle re-entry by urodele muscle cells.
Wound Repair Regen. 6(4):371-81Association of RPA with chromosomal replication origins requires an Mcm protein, and is regulated by Rad53, and cyclin- and Dbf4-dependent kinases.
EMBO J. 17(17):5182-91Early function of Pax5 (BSAP) before the pre-B cell receptor stage of B lymphopoiesis.
J Exp Med. 188(4):735-44Cohesion between sister chromatids must be established during DNA replication.
Curr Biol. 8(20):1095-101Translational fidelity: error-prone versus hyper-accurate ribosomes.
Chem Biol. 5(1):R3-6The transactivation domain AF-2 but not the DNA-binding domain of the estrogen receptor is required to inhibit differentiation of avian erythroid progenitors.
Mol Endocrinol. 12(2):263-77Regulation of the cyclin B degradation system by an inhibitor of mitotic proteolysis.
Mol Biol Cell. 9(7):1817-31Mammalian granulocyte-macrophage colony-stimulating factor receptor expressed in primary avian hematopoietic progenitors: lineage-specific regulation of proliferation and differentiation.
J Cell Biol. 141(4):1041-51Identification of a cullin homology region in a subunit of the anaphase-promoting complex.
Science. 279(5354):1219-22Control of cyclin ubiquitination by CDK-regulated binding of Hct1 to the anaphase promoting complex.
Science. 282(5394):1721-4Mass spectrometric analysis of the anaphase-promoting complex from yeast: identification of a subunit related to cullins.
Science. 279(5354):1216-9Defective induction but normal activation and function of p53 in mouse cells lacking poly-ADP-ribose polymerase.
Oncogene. 15(9):1035-41Delivery of bacterial artificial chromosomes into mammalian cells with psoralen-inactivated adenovirus carrier.
Nucleic Acids Res. 25(10):1950-6Polyethylenimine (PEI) is a simple, inexpensive and effective reagent for condensing and linking plasmid DNA to adenovirus for gene delivery.
Gene Ther. 4(8):773-82Analysis of the requirement for beta 2-microglobulin for expression and formation of human CD1 antigens.
Eur J Immunol. 27(6):1366-73Mechanism of transformation by v-ErbA: substitution for steroid hormone receptor function in self renewal induction.
Oncogene. 15(6):701-15Cell Biologists sort things out: Analysis and purification of intracellular organelles by flow cytometry.
Trends Cell Biology. 7: 499-503Fluorescence activated sorting of endocytic organelles.
Cell Biology - a laboratory handbook. 2:63-69Cell biologists sort things out: Analysis and purification of intracellular organelles by flow cytometry.
Trends Cell Biol. 7(12):499-503Isolation and amino acid sequence analysis reveal an ancient evolutionary origin of the cleavage stage (CS) histones of the sea urchin.
Eur J Biochem. 247(3):784-91Podoplanin, novel 43-kd membrane protein of glomerular epithelial cells, is down-regulated in puromycin nephrosis.
Am J Pathol. 151(4):1141-52Transloading of tumor antigen-derived peptides into antigen-presenting cells.
Proc Natl Acad Sci U S A. 94(7):3256-61Identification of a novel antiapoptotic protein, GAM-1, encoded by the CELO adenovirus.
J Virol. 71(4):3168-77ICE-proteases mediate HTLV-I Tax-induced apoptotic T-cell death.
Oncogene. 14(19):2265-72The role of fibroblast growth factors in tumor progression and angiogenesis.
Tumour Angiogenesis (eds. Bicknell, R., Lewis, CE., Ferrara, N.). :201-38Novel forms of acidic fibroblast growth factor-1 are constitutively exported by beta tumor cell lines independent from conventional secretion and apoptosis.
Angiogenesis. 1(1):55-70In vitro targeting and specific transfection of human neuroblastoma cells by chCE7 antibody-mediated gene transfer.
Gene Ther. 4(2):156-61Intracellular delivery of lipopolysaccharide during DNA transfection activates a lipid A-dependent cell death response that can be prevented by polymyxin B.
Hum Gene Ther. 8(5):555-61The characterization of novel Pax genes of the sea urchin and Drosophila reveal an ancient evolutionary origin of the Pax2/5/8 subfamily.
Mech Dev. 67(2):179-92Regulation of human epsilon germline transcription: role of B-cell-specific activator protein.
Int Arch Allergy Immunol. 113(1-3):35-8A requirement for Rho and Cdc42 during cytokinesis in Xenopus embryos.
Curr Biol. 7(1):12-23Subcellular fractionation of polarized epithelial cells and identification of organelle-specific proteins by two-dimensional gel electrophoresis.
Electrophoresis. 18(14):2582-90Structure and erythroid cell-restricted expression of a chicken cDNA encoding a novel zinc finger protein of the Cys + His class.
Gene. 195(2):277-84The absence of c-fos prevents light-induced apoptotic cell death of photoreceptors in retinal degeneration in vivo.
Nat Med. 3(3):346-9The anaphase-promoting complex is required in G1 arrested yeast cells to inhibit B-type cyclin accumulation and to prevent uncontrolled entry into S-phase.
J Cell Sci. 110 ( Pt 13):1523-31Extension of chromatin accessibility by nuclear matrix attachment regions.
Nature. 385(6613):269-72APC-mediated proteolysis of Ase1 and the morphogenesis of the mitotic spindle.
Science. 275(5304):1311-4Influence of membrane-active peptides on lipospermine/DNA complex mediated gene transfer.
Bioconjug Chem. 8(2):213-21Mechanisms of asymmetric cell division during animal development.
Curr Opin Cell Biol. 9(6):833-41Alternatively spliced insertions in the paired domain restrict the DNA sequence specificity of Pax6 and Pax8.
EMBO J. 16(22):6793-803Mammalian homologues of the Polycomb-group gene Enhancer of zeste mediate gene silencing in Drosophila heterochromatin and at S. cerevisiae telomeres.
EMBO J. 16(11):3219-32A rapid, quantitative and inexpensive method for detecting apoptosis by flow cytometry in transiently transfected cells.
Nucleic Acids Res. 25(23):4855-7Plasminogen-dependent and -independent proteolytic activity of murine endothelioma cells with targeted inactivation of fibrinolytic genes.
Thromb Haemost. 77(2):362-7Mating type switching in yeast controlled by asymmetric localization of ASH1 mRNA.
Science. 277(5324):383-7The five cleavage-stage (CS) histones of the sea urchin are encoded by a maternally expressed family of replacement histone genes: functional equivalence of the CS H1 and frog H1M (B4) proteins.
Mol Cell Biol. 17(3):1189-200Canine tumour suppressor gene p53--mutation in a case of adenoma of circumanal glands.
Vet Res Commun. 21(5):369-73Long-range interactions at the HO promoter.
Mol Cell Biol. 17(5):2669-78Gene transfer mediated by influenza virus peptides: the role of peptide sequences.
New J. Chem. . 21:105-11Cohesins: chromosomal proteins that prevent premature separation of sister chromatids.
Cell. 91(1):35-45Dynamics of cell cycle regulators: artifact-free analysis by recultivation of cells synchronized by centrifugal elutriation.
DNA Cell Biol. 16(7):849-59Genetic interaction between PARP and DNA-PK in V(D)J recombination and tumorigenesis.
Nat Genet. 17(4):479-82The cytoskeleton in mRNA localization and cell differentiation.
Curr Opin Cell Biol. 9(3):396-400Permeabilization of mammalian cells to proteins: poliovirus 2A(pro) as a probe to analyze entry of proteins into cells.
Exp Cell Res. 232(1):186-90Essential functions of Pax-5 (BSAP) in pro-B cell development.
Immunobiology. 198(1-3):227-35Essential functions of Pax5 (BSAP) in pro-B cell development: difference between fetal and adult B lymphopoiesis and reduced V-to-DJ recombination at the IgH locus.
Genes Dev. 11(4):476-91Preparative two-dimensional gel electrophoresis of membrane proteins.
Electrophoresis. 18(14):2573-81Endothelial cells transformed by polyomavirus middle-T oncogene: A model for hemangiomas and other vascular tumors.
Tumour Angiogenesis (eds. Bicknell, R., Lewis, CE., Ferrara, N.). :309-31Is the yeast anaphase promoting complex needed to prevent re-replication during G2 and M phases?
EMBO J. 16(19):5988-97Cooperation of Spi-1/PU.1 with an activated erythropoietin receptor inhibits apoptosis and Epo-dependent differentiation in primary erythroblasts and induces their Kit ligand-dependent proliferation.
EMBO J. 16(18):5639-53Regulation of ES cell differentiation by functional and conformational modulation of p53.
EMBO J. 16(20):6217-29Polyoma middle T-induced vascular tumor formation: the role of the plasminogen activator/plasmin system.
J Cell Biol. 137(4):953-63Cell-free tumor antigen peptide-based cancer vaccines.
Proc Natl Acad Sci U S A. 94(7):3262-7Generation of effective cancer vaccines genetically engineered to secrete cytokines using adenovirus-enhanced transferrinfection (AVET).
Gene. 190(1):211-6Structure and chromosomal assignment of the mouse fra-1 gene, and its exclusion as a candidate gene for oc (osteosclerosis).
Oncogene. 15(10):1171-8Cloning and functional characterization of the ornithokinin receptor. Recognition of the major kinin receptor antagonist, HOE140, as a full agonist.
J Biol Chem. 272(19):12475-81Conserved biological function between Pax-2 and Pax-5 in midbrain and cerebellum development: evidence from targeted mutations.
Proc Natl Acad Sci U S A. 94(26):14518-23Two-dimensional gel electrophoresis analysis of endovacuolar organelles.
Electrophoresis. 18(14):2566-72Phase I study to the immunotherapy of metastatic malignant melanoma by a cancer vaccine consisting of autologous cancer cells transfected with the human IL-2 gene.
J Mol Med (Berl). 75(4):297-9Stabilization of gene delivery systems by freeze-drying.
Int J Pharm. 157(2):233-238Newt myotubes reenter the cell cycle by phosphorylation of the retinoblastoma protein.
J Cell Biol. 136(1):155-65Loading of an Mcm protein onto DNA replication origins is regulated by Cdc6p and CDKs.
Cell. 90(4):649-60Two-dimensional mapping of the endogenous proteins of the rat hepatocyte Golgi complex cleared of proteins in transit.
Electrophoresis. 18(14):2601-12The transcription factor B cell-specific activator protein (BSAP) enhances both IL-4- and CD40-mediated activation of the human epsilon germline promoter.
J Immunol. 158(12):5874-82Cooperation of Pax2 and Pax5 in midbrain and cerebellum development.
Proc Natl Acad Sci U S A. 94(11):5703-8Stem cell factor stimulates chicken osteoclast activity in vitro.
FASEB J. 11(4):287-93Arrest of mycobacterial phagosome maturation is caused by a block in vesicle fusion between stages controlled by rab5 and rab7.
J Biol Chem. 272(20):13326-31In search of differentially expressed genes and proteins.
Biochim Biophys Acta. 1359(3):187-99Generation of completely embryonic stem cell-derived mutant mice using tetraploid blastocyst injection.
Mech Dev. 62(2):137-45PARP is important for genomic stability but dispensable in apoptosis.
Genes Dev. 11(18):2347-58The glucocorticoid receptor is a key regulator of the decision between self-renewal and differentiation in erythroid progenitors.
EMBO J. 16(2):267-80Distinct roles of the receptor tyrosine kinases c-ErbB and c-Kit in regulating the balance between erythroid cell proliferation and differentiation.
Cell Growth Differ. 8(5):481-93CDK1 inactivation regulates anaphase spindle dynamics and cytokinesis in vivo.
J Cell Biol. 138(2):385-93STAT5 involvement in the differentiation response of primary chicken myeloid progenitor cells to chicken myelomonocytic growth factor.
J Immunol. 159(2):877-86[Receptor mediated gene transfer in squamous epithelial carcinoma of the head-neck area].
Laryngorhinootologie. 76(7):411-4Imprinted expression of the Igf2r gene depends on an intronic CpG island.
Nature. 389(6652):745-9Crystal structure of the DNA-binding domain of Mbp1, a transcription factor important in cell-cycle control of DNA synthesis.
Structure. 5(3):349-58Glycerol and polylysine synergize in their ability to rupture vesicular membranes: a mechanism for increased transferrin-polylysine-mediated gene transfer.
Exp Cell Res. 232(1):137-45Topogenesis of a nucleolar protein: determination of molecular segments directing nucleolar association.
Mol Biol Cell. 8(2):231-48Avian stem cell factor (SCF): production and characterization of the recombinant His-tagged SCF of chicken and its neutralizing antibody.
Cytokine. 8(1):14-20Avian erythropoiesis and erythroleukemia: towards understanding the role of the biomolecules involved.
Biochim Biophys Acta. 1288(3):M35-47Self renewal and differentiation in primary avian hematopoietic cells: an alternative to mammalian in vitro models?
Curr Top Microbiol Immunol. 211:29-39Inhibition of HIV-1 replication in lymphocytes by mutants of the Rev cofactor eIF-5A.
Science. 271(5257):1858-60Asymmetric accumulation of Ash1p in postanaphase nuclei depends on a myosin and restricts yeast mating-type switching to mother cells.
Cell. 84(5):699-709Regulation and function of transcription factor GATA-1 during red blood cell differentiation.
Development. 122(12):3839-50Deregulation of PAX-5 by translocation of the Emu enhancer of the IgH locus adjacent to two alternative PAX-5 promoters in a diffuse large-cell lymphoma.
Proc Natl Acad Sci U S A. 93(12):6129-34Cellular responses to adenovirus entry.
Gene Therapy for Diseases of the Lung (ed. Brigham, KL.).The complete DNA sequence and genomic organization of the avian adenovirus CELO.
J Virol. 70(5):2939-49An essential role for the Cdc6 protein in forming the pre-replicative complexes of budding yeast.
Nature. 379(6561):180-2Receptor-mediated gene delivery.
Falk Symposium no. 88, Molecular Diagnosis and Gene Therapy.High primer concentration improves PCR amplification from random pools.
Nucleic Acids Res. 24(5):985-6C-terminal activating and inhibitory domains determine the transactivation potential of BSAP (Pax-5), Pax-2 and Pax-8.
EMBO J. 15(8):1971-82Cell cycle regulation of p70 S6 kinase and p42/p44 mitogen-activated protein kinases in Swiss mouse 3T3 fibroblasts.
J Biol Chem. 271(2):963-71Cloning and characterization of CpG islands of the human chromosome 1p36 region.
Genomics. 32(1):155-8The estrogen-dependent c-JunER protein causes a reversible loss of mammary epithelial cell polarity involving a destabilization of adherens junctions.
J Cell Biol. 132(6):1115-32Regulation of bone cell differentiation and bone remodelling by the c-Fos/AP-1 transcription factor.
Principles of Bone Biology. :15-24Transgenic mouse models of tumour angiogenesis: the angiogenic switch, its molecular controls, and prospects for preclinical therapeutic models.
Eur J Cancer. 32A(14):2386-93Development of a rapid means of estimating the haemoglobin F content of candidate fetal cells isolated from maternal blood using HPLC.
Prenat Diagn. 16(11):1011-9Endosomal fractions from viral K-ras-transformed MDCK cells reveal transformation specific changes on two-dimensional gel maps.
Electrophoresis. 17(11):1734-40Mother cell-specific HO expression in budding yeast depends on the unconventional myosin myo4p and other cytoplasmic proteins.
Cell. 84(5):687-97The transcription factor Swi5 regulates expression of the cyclin kinase inhibitor p40SIC1.
Mol Cell Biol. 16(10):5701-7Switching transcription on and off during the yeast cell cycle: Cln/Cdc28 kinases activate bound transcription factor SBF (Swi4/Swi6) at start, whereas Clb/Cdc28 kinases displace it from the promoter in G2.
Genes Dev. 10(2):129-41EGT2 gene transcription is induced predominantly by Swi5 in early G1.
Mol Cell Biol. 16(7):3264-74p72: a human nuclear DEAD box protein highly related to p68.
Nucleic Acids Res. 24(19):3739-47The Saccharomyces cerevisiae zinc finger proteins Msn2p and Msn4p are required for transcriptional induction through the stress response element (STRE).
EMBO J. 15(9):2227-35Activation of Stat 5b in erythroid progenitors correlates with the ability of ErbB to induce sustained cell proliferation.
Proc Natl Acad Sci U S A. 93(18):9600-5Extrachromosomal recombination occurs efficiently in cells defective in various DNA repair systems.
Nucleic Acids Res. 24(11):2053-8Cell cycle regulation and erythroid differentiation.
Curr Top Microbiol Immunol. 212:175-94Multiple roles for DNA methylation in gametic imprinting.
Curr Opin Genet Dev. 6(2):159-63Hybrid proteins between Pseudomonas aeruginosa exotoxin A and poliovirus 2Apro cleave p220 in HeLa cells.
J Virol. 70(5):3319-24Stochastic dynamics of the nerve growth cone and its microtubules during neurite outgrowth.
Biotechnol Bioeng. 50(4):452-61TGF-beta1 and Ha-Ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells.
Genes Dev. 10(19):2462-77Antiangiogenic therapy of transgenic mice impairs de novo tumor growth.
Proc Natl Acad Sci U S A. 93(5):2002-7Activation of S-phase-promoting CDKs in late G1 defines a "point of no return" after which Cdc6 synthesis cannot promote DNA replication in yeast.
Genes Dev. 10(12):1516-31Activation of the complement system by synthetic DNA complexes: a potential barrier for intravenous gene delivery.
Hum Gene Ther. 7(12):1437-46Normal brainstem auditory evoked potentials in Pax5-deficient mice despite morphologic alterations in the auditory midbrain region.
Audiology. 35(1):55-61Transloading of tumor cells with foreign major histocompatibility complex class I peptide ligand: a novel general strategy for the generation of potent cancer vaccines.
Proc Natl Acad Sci U S A. 93(18):9759-63The human ubiquitin C promoter directs high ubiquitous expression of transgenes in mice.
Nucleic Acids Res. 24(9):1787-8The Lx1 gene maps to mouse chromosome 17 and codes for a protein that is homologous to glucose and polyspecific transmembrane transporters.
Mamm Genome. 7(10):735-40Tumor cells expressing a recall antigen are powerful cancer vaccines.
Eur J Immunol. 26(11):2559-64Adenovirus-enhanced receptor-mediated transferrinfection for the generation of tumor vaccines.
Cytokines Mol Ther. 2(3):185-91Depletion of naive T cells of the peripheral lymph nodes abrogates systemic antitumor protection conferred by IL-2 secreting cancer vaccines.
Gene Ther. 3(9):819-24Cell cycle control of DNA replication in Saccharomyces cerevisiae.
Eukaryotic DNA Replication - Frontiers in Molecular Biology - OUP. :165-96The Saccharomyces cerevisiae Start-specific transcription factor Swi4 interacts through the ankyrin repeats with the mitotic Clb2/Cdc28 kinase and through its conserved carboxy terminus with Swi6.
Mol Cell Biol. 16(6):2647-55Analysis of location and integrity of the human PITSLRE (p58CDC2L1) genes in neuroblastoma cell genomes. evidence against involvement in tumorigenesis.
Int. J. Oncol.. 8:1137-42Structural requirements for low-pH-induced rearrangements in the envelope glycoprotein of tick-borne encephalitis virus.
J Virol. 70(11):8142-7Adenovirus enhanced receptor mediated transferrinfection (AVET) applied to the generation of tumor vaccines.
OECD Biotechnology, Gene Delivery Systems, A state-of-the-Art Review. :153-62Receptor-mediated gene delivery with synthetic virus-like particles.
Targeting of Drugs 5: Strategies for Oligonucleotide and Gene Delivery in Therapy (eds. Gregoriadis, McCormack).Report of the second international workshop on human chromosome 1 mapping 1995.
Cytogenet Cell Genet. 72(2-3):114-44TPR proteins required for anaphase progression mediate ubiquitination of mitotic B-type cyclins in yeast.
Mol Biol Cell. 7(5):791-801Identification of subunits of the anaphase-promoting complex of Saccharomyces cerevisiae.
Science. 274(5290):1201-4Glycerol enhancement of ligand-polylysine/DNA transfection.
Biotechniques. 20(5):905-13On the biological role of the nuclear polymerizing NAD+: protein(ADP-ribosyl) transferase (ADPRT): ADPRT from Dictyostelium discoideum and inactivation of the ADPRT gene in the mouse.
Biochimie. 77(6):444-9Determination and regional assignment of grouped sets of microclones in chromosome 1pter-p35.
Genomics. 29(3):607-15Transcriptional activation of the fra-1 gene by AP-1 is mediated by regulatory sequences in the first intron.
Mol Cell Biol. 15(7):3748-58In vitro growth of factor-dependent multipotential hematopoietic cells is induced by the nuclear oncoprotein v-Ski.
Oncogene. 11(1):59-72Transformation of erythroid progenitors by viral and cellular tyrosine kinases.
Cell Growth Differ. 6(8):999-1008Avian hematopoietic cell culture: in vitro model systems to study oncogenic transformation of hematopoietic cells.
Methods Enzymol. 254:41-76Dendritic cell progenitor is transformed by a conditional v-Rel estrogen receptor fusion protein v-RelER.
Cell. 80(2):341-52v-rel protects transformed chicken bone marrow cells from apoptosis: A study with the conditional v-rel estrogen receptor fusion oncoprotein v-rel ER.
Advances in Avian Immunology Research (eds. Davison, TF., Bumstead, N., Kaiser, P.). :65-73Cell proliferation and cell cycle progression are not impaired in fibroblasts and ES cells lacking c-Fos.
Oncogene. 10(1):79-86Receptor-mediated gene transfer into human T lymphocytes via binding of DNA/CD3 antibody particles to the CD3 T cell receptor complex.
Hum Gene Ther. 6(6):753-61The role of BSAP (Pax-5) in B-cell development.
Curr Opin Genet Dev. 5(5):595-601Immediate effects of reversible HTLV-1 tax function: T-cell activation and apoptosis.
Oncogene. 10(2):269-77The entry mechanism of adenovirus and some solutions to the toxicity problems associated with adenovirus-augmented, receptor-mediated gene delivery.
The Molecular Repertoire of Adenoviruses III (eds. Doerfler, W., Böhm, P.).Adenovirus-augmented, receptor-mediated gene delivery and some solutions to the common toxicity problems.
Curr Top Microbiol Immunol. 199 ( Pt 3):283-95The adenovirus protease is required for virus entry into host cells.
Virology. 213(2):494-502Ste20-like protein kinases are required for normal localization of cell growth and for cytokinesis in budding yeast.
Genes Dev. 9(15):1817-30DNA-binding and transactivation properties of Pax-6: three amino acids in the paired domain are responsible for the different sequence recognition of Pax-6 and BSAP (Pax-5).
Mol Cell Biol. 15(5):2858-71S-phase-promoting cyclin-dependent kinases prevent re-replication by inhibiting the transition of replication origins to a pre-replicative state.
Curr Biol. 5(11):1257-69Induction of the mitogen-activated p70 S6 kinase by adenovirus E1A.
Oncogene. 10(3):543-8Roles and regulation of Cln-Cdc28 kinases at the start of the cell cycle of Saccharomyces cerevisiae.
EMBO J. 14(19):4803-13Terminal differentiation of normal chicken erythroid progenitors: shortening of G1 correlates with loss of D-cyclin/cdk4 expression and altered cell size control.
Cell Growth Differ. 6(11):1341-52Expression of the helix-loop-helix gene Id3 during murine embryonic development.
Dev Dyn. 203(2):163-73Expression of interstitial collagenase during skeletal development of the mouse is restricted to osteoblast-like cells and hypertrophic chondrocytes.
Cell Growth Differ. 6(6):759-67Fos and bone cell development: lessons from a nuclear oncogene.
Trends Genet. 11(11):436-41Inactivation of the poly(ADP-ribose) polymerase gene affects oxygen radical and nitric oxide toxicity in islet cells.
J Biol Chem. 270(19):11176-80Genes involved in sister chromatid separation are needed for B-type cyclin proteolysis in budding yeast.
Cell. 81(2):269-78Cyclin-dependent kinase site-regulated signal-dependent nuclear localization of the SW15 yeast transcription factor in mammalian cells.
J Biol Chem. 270(29):17064-7A novel class of autoantigens of anti-neutrophil cytoplasmic antibodies in necrotizing and crescentic glomerulonephritis: the lysosomal membrane glycoprotein h-lamp-2 in neutrophil granulocytes and a related membrane protein in glomerular endothelial cells.
J Exp Med. 181(2):585-97Deregulated expression of PAX5 in medulloblastoma.
Proc Natl Acad Sci U S A. 92(12):5709-13Thyroid hormone regulates stromelysin expression, protease secretion and the morphogenetic potential of normal polarized mammary epithelial cells.
EMBO J. 14(6):1145-55Priming of tumor-specific T cells in the draining lymph nodes after immunization with interleukin 2-secreting tumor cells: three consecutive stages may be required for successful tumor vaccination.
Proc Natl Acad Sci U S A. 92(12):5540-4Tumor vaccines: effects and fate of IL-2 transfected murine melanoma cells in vivo.
Int J Immunopharmacol. 17(2):65-73Cell cycle-regulated transcription of the CLB2 gene is dependent on Mcm1 and a ternary complex factor.
Mol Cell Biol. 15(6):3129-37Activation of HIV transcription by human foamy virus in transgenic mice.
Lab Invest. 73(1):103-10Sequence of an exon of tumour suppressor p53 gene--a comparative study in domestic animals: mutation in a feline solid mammary carcinoma.
Br Vet J. 151(3):325-9Mutations in tumour suppressor gene p53 in two feline fibrosarcomas.
Br Vet J. 151(6):707-13Direct microdissection and microcloning of a translocation breakpoint region, t(1;11)(q42.2;q21), associated with schizophrenia.
Cytogenet Cell Genet. 70(1-2):35-40Evolution of the cell cycle.
Philos Trans R Soc Lond B Biol Sci. 349(1329):271-81Characteristics of imprinted genes.
Nat Genet. 9(1):12-3Activation of p70 S6 kinase and erk-encoded mitogen-activated protein kinases is resistant to high cyclic nucleotide levels in Swiss 3T3 fibroblasts.
J Biol Chem. 270(44):26619-25Selective inhibition of p70 S6 kinase activation by phosphatidylinositol 3-kinase inhibitors.
Eur J Biochem. 230(2):431-8Cdc6 is an unstable protein whose de novo synthesis in G1 is important for the onset of S phase and for preventing a 'reductional' anaphase in the budding yeast Saccharomyces cerevisiae.
EMBO J. 14(15):3788-99A versatile quick-prep of genomic DNA from gram-positive bacteria.
Trends Genet. 11(6):217-8Spi-1 and mutant p53 regulate different aspects of the proliferation and differentiation control of primary erythroid progenitors.
Oncogene. 11(7):1229-39Low affinity binding of interleukin-1 beta and intracellular signaling via NF-kappa B identify Fit-1 as a distant member of the interleukin-1 receptor family.
J Biol Chem. 270(30):17645-8Cancer vaccines: the interleukin 2 dosage effect.
Proc Natl Acad Sci U S A. 92(10):4711-4Fos is an essential component of the mammalian UV response.
EMBO J. 14(21):5338-49Strain-dependent epithelial defects in mice lacking the EGF receptor.
Science. 269(5221):234-8Conservation of a maternal-specific methylation signal at the human IGF2R locus.
Hum Mol Genet. 4(10):1945-52The gene coding for the B cell surface protein CD19 is localized on human chromosome 16p11.
Hum Genet. 95(2):223-5Primary, self-renewing erythroid progenitors develop through activation of both tyrosine kinase and steroid hormone receptors.
Curr Biol. 5(2):191-204Generation of high-titer retroviral vectors following receptor-mediated, adenovirus-augmented transfection.
Biotechniques. 18(3):484-9The PAX5 gene: a linkage and mutation analysis in candidate human primary immunodeficiencies.
Immunogenetics. 42(2):149-52Mice lacking ADPRT and poly(ADP-ribosyl)ation develop normally but are susceptible to skin disease.
Genes Dev. 9(5):509-20c-fos-induced osteosarcoma formation in transgenic mice: cooperativity with c-jun and the role of endogenous c-fos.
Cancer Res. 55(24):6244-51Genomic imprinting: the parental connection.
Applied Cytogenetics. 21:145-52Elicitation of a systemic and protective anti-melanoma immune response by an IL-2-based vaccine. Assessment of critical cellular and molecular parameters.
J Immunol. 154(7):3406-19Rhinovirus-mediated endosomal release of transfection complexes.
J Virol. 69(2):1085-92Closing the cell cycle circle in yeast: G2 cyclin proteolysis initiated at mitosis persists until the activation of G1 cyclins in the next cycle.
Cell. 77(7):1037-50Receptor-mediated gene delivery employing lectin-binding specificity.
Gene Ther. 1(4):255-60An improved pair potential to recognize native protein folds.
Proteins. 18(3):254-61Alternative promoter usage of the Fos-responsive gene Fit-1 generates mRNA isoforms coding for either secreted or membrane-bound proteins related to the IL-1 receptor.
EMBO J. 13(5):1176-88Insights into erythroid differentiation obtained from studies on avian erythroblastosis virus.
Curr Opin Cell Biol. 6(6):816-24Structure and expression of the chicken retinoblastoma gene.
Cell Growth Differ. 5(2):221-30Identification of AP-1-regulated genes.
The Fos and Jun families of transcription factors (eds. Angel, PE., Herrlich, PA.). :133-50Generation of normal T and B lymphocytes by c-jun deficient embryonic stem cells.
Immunity. 1(1):65-72NK-kappa B subunit-specific regulation of the I kappa B alpha promoter.
J Biol Chem. 269(18):13551-7Lipopolysaccharide is a frequent contaminant of plasmid DNA preparations and can be toxic to primary human cells in the presence of adenovirus.
Gene Ther. 1(4):239-46Psoralen treatment of adenovirus particles eliminates virus replication and transcription while maintaining the endosomolytic activity of the virus capsid.
Virology. 205(1):254-61Efficient foreign gene expression in Epstein-Barr virus-transformed human B-cells.
Virology. 198(2):577-85Positive regulation of the cAMP-responsive activator CREM by the p70 S6 kinase: an alternative route to mitogen-induced gene expression.
Cell. 79(1):81-91Report and abstracts of the First International Workshop on Human Chromosome 1 Mapping 1994. Bethesda, Maryland, March 25-27, 1994.
Cytogenet Cell Genet. 67(3):144-65Introduction: oncogenes and differentiation.
Semin Cancer Biol. 5(2):91-4Characterization of a region-specific library of microclones in the vicinity of the Bcg and splotch loci on mouse chromosome 1.
Genomics. 19(1):163-6High-level expression of various apolipoprotein(a) isoforms by "transferrinfection": the role of kringle IV sequences in the extracellular association with low-density lipoprotein.
Biochemistry. 33(40):12329-39Down-regulation of wild-type p53 activity interferes with apoptosis of IL-3-dependent hematopoietic cells following IL-3 withdrawal.
EMBO J. 13(6):1368-74c-Fos: a key regulator of osteoclast-macrophage lineage determination and bone remodeling.
Science. 266(5184):443-8Thymocyte apoptosis induced by elevated endogenous corticosterone levels.
Eur J Immunol. 24(5):1115-21Two-dimensional gel mapping of small GTPases reveals transformation-specific changes during oncogenesis.
Electrophoresis. 15(3-4):469-73The H1A histone variant is an in vivo repressor of oocyte-type 5S gene transcription in Xenopus laevis embryos.
Proc Natl Acad Sci U S A. 91(15):7257-61Expression of three- and four-repeat tau isoforms in mouse liver.
Hepatology. 20(4 Pt 1):1086-9Endothelial cell transformation by polyomavirus middle T antigen in mice lacking Src-related kinases.
Curr Biol. 4(2):100-9Oncogenic properties of the middle T antigens of polyomaviruses.
Adv Cancer Res. 64:125-57Cell cycle regulated transcription in yeast.
Curr Opin Cell Biol. 6(3):451-9Electroporation of cosmid DNA into bacterial cells.
Trends Genet. 10(1):5Mouse embryonic germ (EG) cell lines: transmission through the germline and differences in the methylation imprint of insulin-like growth factor 2 receptor (Igf2r) gene compared with embryonic stem (ES) cell lines.
Development. 120(11):3197-204Embryonic germ cell lines and their derivation from mouse primordial germ cells.
Ciba Found Symp. 182:157-68; discussion 168-78Generation of alphoid DNA probes for fluorescence in situ hybridization (FISH) using the polymerase chain reaction.
Methods Mol Biol. 33:51-61Large-scale isolation of human 1p36-specific P1 clones and their use for fluorescence in situ hybridization.
Genet Anal Tech Appl. 11(5-6):140-7FISH of Alu-PCR-amplified YAC clones and applications in tumor cytogenetics.
Methods Mol Biol. 33:85-94The transcription factor BSAP (NF-HB) is essential for immunoglobulin germ-line epsilon transcription.
J Immunol. 152(6):2904-11Generation of tumor vaccines by adenovirus-enhanced transfection of cytokine genes into tumor cells.
NATO ASI Series. H88:467-79Degeneration of neural cells in the central nervous system of mice deficient in the gene for the adhesion molecule on Glia, the beta 2 subunit of murine Na,K-ATPase.
J Cell Biol. 127(3):835-45A physical map of the region encompassing the human interleukin-1 alpha, interleukin-1 beta, and interleukin-1 receptor antagonist genes.
Genomics. 19(2):382-4Mice lacking c-fos have normal hematopoietic stem cells but exhibit altered B-cell differentiation due to an impaired bone marrow environment.
Mol Cell Biol. 14(1):382-90The influence of endosome-disruptive peptides on gene transfer using synthetic virus-like gene transfer systems.
J Biol Chem. 269(17):12918-24Molecular cloning and characterization of a human PAX-7 cDNA expressed in normal and neoplastic myocytes.
Nucleic Acids Res. 22(22):4574-82The B-type cyclin kinase inhibitor p40SIC1 controls the G1 to S transition in S. cerevisiae.
Cell. 79(2):233-44Recombinant murine erythropoietin receptor expressed in avian erythroid progenitors mediates terminal erythroid differentiation in vitro.
Growth Factors. 10(1):1-16Carbohydrate receptor-mediated gene transfer to human T leukaemic cells.
Glycobiology. 4(4):429-35Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAP.
Cell. 79(5):901-12Retroviral capture of c-erbB proto-oncogene sequences: rapid evolution of distinct viral genomes carrying mutant v-erbB genes with different transforming capacities.
Oncogene. 9(5):1307-20An intragenic TaqI RFLP at the PAX5 locus.
Hum Mol Genet. 3(4):681SSCP/SacI polymorphism in the PAX5 gene.
Hum Mol Genet. 3(5):839Delivery of drugs, proteins and genes into cells using transferrin as a ligand for receptor-mediated endocytosis.
Advanced Drug Delivery Reviews. 14:113-36Embryonic stem cell as a tool for analyzing mammalian hematopoietic development and disease.
Schering Res. Foundation Workshop. 11:58-67Oncogenes in the study of endothelial cell growth and differentiation.
Semin Cancer Biol. 5(2):137-45Regulation of embryonic growth and lysosomal targeting by the imprinted Igf2/Mpr gene.
Nature. 372(6505):464-7The analysis of disease-specific chromosomal rearrangements with microcloned DNA markers.
Methods in Molecular Genetics (ed. Adolph, K.). 5: Gene and Chromosome Analysis, Part C:169-94In vivo production of human factor VII in mice after intrasplenic implantation of primary fibroblasts transfected by receptor-mediated, adenovirus-augmented gene delivery.
Proc Natl Acad Sci U S A. 91(11):5148-52Genetic modification of cells by receptor-mediated adenovirus-augmented gene delivery: a new approach for immunotherapy of cancer.
Verh Dtsch Ges Pathol. 78:171-6Synthesis and anti-HIV activity of thiocholesteryl-coupled phosphodiester antisense oligonucleotides incorporated into immunoliposomes.
Antiviral Res. 25(1):13-25pct1+, which encodes a new DNA-binding partner of p85cdc10, is required for meiosis in the fission yeast Schizosaccharomyces pombe.
Genes Dev. 8(8):885-98Human foamy virus proteins accumulate in neurons and induce multinucleated giant cells in the brain of transgenic mice.
Am J Pathol. 142(4):1061-71Mechanisms that help the yeast cell cycle clock tick: G2 cyclins transcriptionally activate G2 cyclins and repress G1 cyclins.
Cell. 74(6):993-1007Unliganded T3R, but not its oncogenic variant, v-erbA, suppresses RAR-dependent transactivation by titrating out RXR.
EMBO J. 12(4):1343-54Methylation and imprinting: from host defense to gene regulation?
Science. 260(5106):309-10A hormone-inducible v-rel estrogen receptor fusion as a means to transform early hematopoietic progenitor cells and to study their differentiation pathway.
Les Colloques de I' I.N.R.A.. 62:337-41A selective transcriptional induction system for mammalian cells based on Gal4-estrogen receptor fusion proteins.
Proc Natl Acad Sci U S A. 90(5):1657-61Identification of a gene encoding a novel zinc finger protein in Saccharomyces cerevisiae.
Yeast. 9(5):551-6Ectopic expression of a conditional GATA-2/estrogen receptor chimera arrests erythroid differentiation in a hormone-dependent manner.
Genes Dev. 7(6):1097-109Non-viral approaches to gene therapy.
Curr Opin Biotechnol. 4(6):705-10Receptor-mediated transport of DNA into eukaryotic cells.
Methods Enzymol. 217:618-44Chicken adenovirus (CELO virus) particles augment receptor-mediated DNA delivery to mammalian cells and yield exceptional levels of stable transformants.
J Virol. 67(7):3777-85Yeast G1 cyclins CLN1 and CLN2 and a GAP-like protein have a role in bud formation.
EMBO J. 12(13):5277-86DNA sequence recognition by Pax proteins: bipartite structure of the paired domain and its binding site.
Genes Dev. 7(10):2048-61MAP kinase-related FUS3 from S. cerevisiae is activated by STE7 in vitro.
Nature. 362(6417):261-4Direct in vivo gene transfer to airway epithelium employing adenovirus-polylysine-DNA complexes.
Hum Gene Ther. 4(1):17-24Titin antibodies in myasthenia gravis: identification of a major immunogenic region of titin.
Neurology. 43(8):1581-5Osteoblasts are target cells for transformation in c-fos transgenic mice.
J Cell Biol. 122(3):685-701c-Fos oncogene expression in cartilage and bone tissues of transgenic and chimaeric mice.
Cell. and Mol. of the Bone (ed. Noda, M.). :497-537Self-renewal and differentiation of normal avian erythroid progenitor cells: regulatory roles of the TGF alpha/c-ErbB and SCF/c-kit receptors.
Cell. 74(1):157-69c-jun is essential for normal mouse development and hepatogenesis.
Nature. 365(6442):179-81Encyclopedia of the mouse genome III. October 1993. Mouse chromosome 17.
Mamm Genome. 4 Spec No:S230-52A role for the transcription factors Mbp1 and Swi4 in progression from G1 to S phase.
Science. 261(5128):1551-7Alternative splicing of Pax-8 gene transcripts is developmentally regulated and generates isoforms with different transactivation properties.
Mol Cell Biol. 13(10):6024-35Kettin, a large modular protein in the Z-disc of insect muscles.
EMBO J. 12(7):2863-71Transformation of chicken bone marrow cells by the v-ski oncogene.
Oncogene. 8(12):3221-8Mutational analysis of the role of the carboxy-terminal region of the v-erbB protein in erythroid cell transformation.
Oncogene. 8(5):1317-27Binding-incompetent adenovirus facilitates molecular conjugate-mediated gene transfer by the receptor-mediated endocytosis pathway.
J Biol Chem. 268(10):6866-9Yeast origin recognition complex is involved in DNA replication and transcriptional silencing.
Nature. 366(6450):87-9Transcription factors important for starting the cell cycle in yeast.
Philos Trans R Soc Lond B Biol Sci. 340(1293):351-60Thyroid hormone receptor/c-erbA: control of commitment and differentiation in the neuronal/chromaffin progenitor line PC12.
J Cell Biol. 121(2):423-38Control of the yeast cell cycle by the Cdc28 protein kinase.
Curr Opin Cell Biol. 5(2):166-79Identification of pol-related gene products of human foamy virus.
Virology. 192(1):336-8The glycerol kinase (GUT1) gene of Saccharomyces cerevisiae: cloning and characterization.
Curr Genet. 24(1-2):21-5A conserved C-terminal sequence that is deleted in v-ErbA is essential for the biological activities of c-ErbA (the thyroid hormone receptor).
Mol Cell Biol. 13(6):3675-85The estrogen receptor cooperates with the TGF alpha receptor (c-erbB) in regulation of chicken erythroid progenitor self-renewal.
EMBO J. 12(3):951-60CLB5 and CLB6, a new pair of B cyclins involved in DNA replication in Saccharomyces cerevisiae.
Genes Dev. 7(7A):1160-75Switching genes on at the START of the yeast cell cycle.
The pharmacology of cell differentiation. Esteve Foundation Symposium Volume (ed. Rifkind, RA.). :107-21Chromosomal localization of seven PAX genes and cloning of a novel family member, PAX-9.
Nat Genet. 3(4):292-8Maternal-specific methylation of the imprinted mouse Igf2r locus identifies the expressed locus as carrying the imprinting signal.
Cell. 73(1):61-71Destruction of the CDC28/CLB mitotic kinase is not required for the metaphase to anaphase transition in budding yeast.
EMBO J. 12(5):1969-78SWI5 instability may be necessary but is not sufficient for asymmetric HO expression in yeast.
Genes Dev. 7(3):517-28Induction of tumor formation and cell transformation by polyoma middle T antigen in the absence of Src.
Oncogene. 8(9):2521-9Rescue of W-associated mast cell defects in W/Wv bone marrow cells by ectopic expression of normal and mutant epidermal growth factor receptors.
Blood. 82(5):1463-70Exploring the pathogenic potential of polyoma middle T, c-fos and human foamy virus in transgenic mice.
Transgenic animals as models for human diseases (eds. Theuring, F., Wagner, EF.). 6:109-28Stable murine chondrogenic cell lines derived from c-fos-induced cartilage tumors.
J Bone Miner Res. 8(7):839-47Towards physical linkage map of the human chromosome 1p36 region.
Human Neuroblastoma (ed. Schwab, M.). :251-61Direct transcriptional stimulation of the ornithine decarboxylase gene by Fos in PC12 cells but not in fibroblasts.
Mol Cell Biol. 13(8):4657-69Somatic gene therapy for cancer: the utility of transferrinfection in generating 'tumor vaccines'.
Gene. 135(1-2):199-207Pax-5 encodes the transcription factor BSAP and is expressed in B lymphocytes, the developing CNS, and adult testis.
Genes Dev. 6(9):1589-607Expression of human foamy virus is differentially regulated during development in transgenic mice.
New Biol. 4(3):225-37Human foamy virus: an underestimated neuropathogen?
Brain Pathol. 2(1):61-9Dominant and recessive molecular changes in neuroblastomas.
Brain Pathol. 2(3):195-208Regulation of p34CDC28 tyrosine phosphorylation is not required for entry into mitosis in S. cerevisiae.
Nature. 355(6358):368-71Preparation, restriction and hybridization analysis of mammalian genomic DNA for pulsed-field gel electrophoresis.
Methods, Applications and Theories in Pulsed-Field gel Electrophoresis (eds. Burmeister, M., Ulanovsky, L.). :107-28Independent modulation of differentiation and proliferation in erythroid progenitors.
Nuclear Processes and Oncogenes. :53-84Molecular modeling on garuganin-I.
Monatshefte für Chemie. 123:417-23Hormone-regulated v-rel estrogen receptor fusion protein: reversible induction of cell transformation and cellular gene expression.
EMBO J. 11(12):4641-52A chimaeric mouse model for autosomal-dominant polycystic kidney disease.
Contrib Nephrol. 97:60-70Repression of genes by DNA methylation depends on CpG density and promoter strength: evidence for involvement of a methyl-CpG binding protein.
EMBO J. 11(1):327-33Identification of Fos target genes by the use of selective induction systems.
J Cell Sci Suppl. 16:97-109Angiogenic activity of the K-fgf/hst oncogene in neural transplants.
Oncogene. 7(6):1177-83High-efficiency receptor-mediated delivery of small and large (48 kilobase gene constructs using the endosome-disruption activity of defective or chemically inactivated adenovirus particles.
Proc Natl Acad Sci U S A. 89(13):6094-8Gene transfer to respiratory epithelial cells via the receptor-mediated endocytosis pathway.
Am J Respir Cell Mol Biol. 6(3):247-52High-efficiency gene transfer mediated by adenovirus coupled to DNA-polylysine complexes.
Hum Gene Ther. 3(2):147-54A central role for SWI6 in modulating cell cycle Start-specific transcription in yeast.
Nature. 357(6378):508-13Evolutionary conserved multiprotein complexes interact with the 3' untranslated region of histone transcripts.
Nucleic Acids Res. 20(5):1023-30Mutually exclusive expression of a helix-loop-helix gene and N-myc in human neuroblastomas and in normal development.
EMBO J. 11(7):2563-71cis and trans regulation of tissue-specific transcription.
J Cell Sci Suppl. 16:21-31Characterization of four B-type cyclin genes of the budding yeast Saccharomyces cerevisiae.
Mol Biol Cell. 3(7):805-18Transcriptional repression of band 3 and CAII in v-erbA transformed erythroblasts accounts for an important part of the leukaemic phenotype.
EMBO J. 11(9):3355-65Signal transduction in Saccharomyces cerevisiae requires tyrosine and threonine phosphorylation of FUS3 and KSS1.
Genes Dev. 6(7):1280-92The leukaemia oncogene v-erbA: a dominant negative version of ligand dependent transcription factors that regulates red cell differentiation?
Cancer Surv. 14:169-80Avian erythroblastosis: a model system to study oncogene co-operation in leukemia.
Cancer Surv. 15:53-68Embryonic stem (ES) cells lacking functional c-jun: consequences for growth and differentiation, AP-1 activity and tumorigenicity.
Oncogene. 7(12):2371-80Dexamethasone selectively regulates the activity of enzymatic markers of cerebral endothelial cell lines.
In Vitro Cell Dev Biol. 28A(7-8):537-43Factor-dependent erythroid cell lines derived from mice transplanted with hematopoietic cells expressing the v-src oncogene.
Blood. 79(1):180-90Characterization of early and late endocytic compartments of the transferrin cycle. Transferrin receptor antibody blocks erythroid differentiation by trapping the receptor in the early endosome.
J Cell Sci. 103 ( Pt 1):211-32The promoter of the CD19 gene is a target for the B-cell-specific transcription factor BSAP.
Mol Cell Biol. 12(6):2662-72The v-ski oncogene cooperates with the v-sea oncogene in erythroid transformation by blocking erythroid differentiation.
Oncogene. 7(10):1903-11Histone H4 mRNA levels are down-regulated by 3' RNA processing during terminal differentiation of myoblasts.
Biochim Biophys Acta. 1131(2):139-44SWI6 is a regulatory subunit of two different cell cycle START-dependent transcription factors in Saccharomyces cerevisiae.
J Cell Sci Suppl. 16:87-96Mutations in the rel-homology domain alter the biochemical properties of v-rel and render it transformation defective in chicken embryo fibroblasts.
Oncogene. 7(6):1137-47How do cells control the timing of DNA replication and mitosis?
Harvey Lect. 88:141-71Effective incorporation of 2'-O-methyl-oligoribonucleotides into liposomes and enhanced cell association through modification with thiocholesterol.
Nucleic Acids Res. 20(3):533-8A new method for the isolation of recombinant baculovirus.
Nucleic Acids Res. 20(1):97-104Amphibian oocytes and sphere organelles: are the U snRNA genes amplified?
Chromosoma. 101(9):549-56Analysis of a gene cluster coding for the Xenopus laevis U7 snRNA.
Biochim Biophys Acta. 1131(1):95-8Gene transfer into hepatocytes using asialoglycoprotein receptor mediated endocytosis of DNA complexed with an artificial tetra-antennary galactose ligand.
Bioconjug Chem. 3(6):533-9Anatomy of a transcription factor important for the start of the cell cycle in Saccharomyces cerevisiae.
Nature. 358(6387):593-7Constitutive myc expression impairs hypertrophy and calcification in cartilage.
Dev Biol. 149(1):168-76Anti-oncogenic activity of signalling-defective epidermal growth factor receptor mutants.
Mol Cell Biol. 12(2):491-8Activation of an inducible c-FosER fusion protein causes loss of epithelial polarity and triggers epithelial-fibroblastoid cell conversion.
Cell. 71(7):1103-16The v-erbA oncogene requires cooperation with tyrosine kinases to arrest erythroid differentiation induced by ligand-activated endogenous c-erbA and retinoic acid receptor.
Oncogene. 7(2):203-16Modulation of normal erythroid differentiation by the endogenous thyroid hormone and retinoic acid receptors: a possible target for v-erbA oncogene action.
Oncogene. 7(2):217-27The mouse plasminogen locus maps to the recombination breakpoints of the tLub2 and TtOrl partial t haplotypes but is not at the tw73 locus.
Mamm Genome. 2(4):260-8Mouse Chromosome 17
Mammalian Genome. 3(1 Supplement):S241-S260Mouse chromosome 17.
Mamm Genome. 3 Spec No:S241-60The SRF and MCM1 transcription factors.
Curr Opin Genet Dev. 2(2):221-6Immortalization of conditionally transformed chicken cells: loss of normal p53 expression is an early step that is independent of cell transformation.
Genes Dev. 6(5):876-87Identification and mapping of six microdissected genomic DNA probes to the proximal region of mouse chromosome 1.
Genomics. 14(1):32-7Development of a lethal mast cell disease in mice reconstituted with bone marrow cells expressing the v-erbB oncogene.
Blood. 79(12):3145-58Influenza virus hemagglutinin HA-2 N-terminal fusogenic peptides augment gene transfer by transferrin-polylysine-DNA complexes: toward a synthetic virus-like gene-transfer vehicle.
Proc Natl Acad Sci U S A. 89(17):7934-8Coupling of adenovirus to transferrin-polylysine/DNA complexes greatly enhances receptor-mediated gene delivery and expression of transfected genes.
Proc Natl Acad Sci U S A. 89(13):6099-103Towards a molecular understanding of mammalian development and disease?
Proc. of the 10th Discoveries Symposium "Basic Life Sciences and Human Society", Alexander von Humboldt Foundation. :63-71Bone and haematopoietic defects in mice lacking c-fos.
Nature. 360(6406):741-5Oncogene complementation in fetal brain transplants.
Cancer Res. 52(13):3760-7Retrovirus-mediated oncogene transfer into neural transplants.
Brain Pathol. 2(1):47-59Transferrinfection: a highly efficient way to express gene constructs in eukaryotic cells.
Ann N Y Acad Sci. 660:136-53Homologous recombination in embryonic stem cells as a means to generate mice with defined mutations.
Mechanisms of Eukaryotic DNA Recombination (eds. Gottesman, ME., Vogel, HZ.). :29-40Maps of mouse chromosome 17: first report. Committee for Mouse Chromosome 17.
Mamm Genome. 1(1):5-29Cell type-specific tumor induction in neural transplants by retrovirus-mediated oncogene transfer.
Oncogene. 6(1):113-8Expression of functional c-kit receptors rescues the genetic defect of W mutant mast cells.
EMBO J. 10(12):3683-91Mouse chromosome 17.
Mamm Genome. 1 Spec No:S280-300The mouse insulin-like growth factor type-2 receptor is imprinted and closely linked to the Tme locus.
Nature. 349(6304):84-7Primary structure and expression of a chicken cDNA encoding a protein with zinc-finger motifs.
Gene. 106(2):207-12Avian erythroleukemia: Possible mechanisms involved in v-erbA oncogene function.
Nuclear Hormone Receptors (ed. Parker, MD.). :355-75Expression of v-src induces aberrant development and twinning in chimaeric mice.
Development. 111(2):357-66DNA methylation inhibits transcription indirectly via a methyl-CpG binding protein.
Cell. 64(6):1123-34Early fetal hematopoietic development from in vitro differentiated embryonic stem cells.
New Biol. 3(7):698-7082'-O-methyl, 2'-O-ethyl oligoribonucleotides and phosphorothioate oligodeoxyribonucleotides as inhibitors of the in vitro U7 snRNP-dependent mRNA processing event.
Nucleic Acids Res. 19(10):2629-35Non-methylated islands in fish genomes are GC-poor.
Nucleic Acids Res. 19(7):1469-74Adenovirus enhancement of transferrin-polylysine-mediated gene delivery.
Proc Natl Acad Sci U S A. 88(19):8850-4Positive feedback in the activation of G1 cyclins in yeast.
Nature. 351(6329):754-7v-erbA overexpression is required to extinguish c-erbA function in erythroid cell differentiation and regulation of the erbA target gene CAII.
Genes Dev. 5(11):2033-47The v-erbA oncoprotein efficiently suppresses erythrocyte-specific CA II expression.
Proceedings on carbonic anhydrases (ed. Botrè, F., Gros, G., Storey, BT.. :139-43Transcripts from amplified sequences of an inherited homogeneously staining region in chromosome 1 of the house mouse (Mus musculus).
Mol Cell Biol. 11(4):2229-35Mature mRNA 3' end formation stimulates RNA export from the nucleus.
EMBO J. 10(11):3513-22Localization of regulatory elements controlling human MYCN expression.
Oncogene. 6(6):969-77EGF promotes in vivo tumorigenic growth of primary chicken embryo fibroblasts expressing v-myc and enhances in vitro transformation by the v-erbA oncogene.
Oncogene. 6(1):21-8Fractionation of mouse bone marrow by adherence separates primitive hematopoietic stem cells from in vitro colony-forming cells and spleen colony-forming cells.
Blood. 78(10):2577-82Painting of defined chromosomal regions by in situ suppression hybridization of libraries from laser-microdissected chromosomes.
Cytogenet Cell Genet. 56(1):27-30A new role for MCM1 in yeast: cell cycle regulation of SW15 transcription.
Genes Dev. 5(12B):2405-19The role of phosphorylation and the CDC28 protein kinase in cell cycle-regulated nuclear import of the S. cerevisiae transcription factor SWI5.
Cell. 66(4):743-58Expression of v-rel in a replication competent virus: transformation and biochemical characterization.
Oncogene. 6(9):1657-66Genetic maps of mouse chromosome 17 including 12 new anonymous DNA loci and 25 anchor loci.
Genomics. 9(1):78-89Cell cycle research proliferates. The Research Institute of Molecular Pathology (I.M.P.). Fourth International Conference on the Control of Proliferation in Normal and Malignant Cells, Vienna, Austria, May 3-5, 1991.
New Biol. 3(10):955-8The role of SWI4 and SWI6 in the activity of G1 cyclins in yeast.
Cell. 66(5):995-1013Some facts and thoughts on cell cycle control in yeast.
Cold Spring Harb Symp Quant Biol. 56:9-20A single site mutation in a truncated Fos protein allows it to interact with the TRE in vitro.
Oncogene. 6(1):173-9A general approach to the isolation of cell cycle-regulated genes in the budding yeast, Saccharomyces cerevisiae.
J Mol Biol. 218(3):543-56The DNA binding and oligomerization domain of MCM1 is sufficient for its interaction with other regulatory proteins.
EMBO J. 10(13):4209-18Abnormalities of chromosome 1 and loss of heterozygosity on 1p in primary hepatomas.
Oncogene. 6(5):765-70Two-step affinity purification of U7 small nuclear ribonucleoprotein particles using complementary biotinylated 2'-O-methyl oligoribonucleotides.
Proc Natl Acad Sci U S A. 88(21):9784-8Hormone-dependent transcriptional regulation and cellular transformation by Fos-steroid receptor fusion proteins.
Proc Natl Acad Sci U S A. 88(12):5114-8The role of CDC28 and cyclins during mitosis in the budding yeast S. cerevisiae.
Cell. 65(1):145-61Changes in a SWI4,6-DNA-binding complex occur at the time of HO gene activation in yeast.
Genes Dev. 5(11):2000-13Microtubule behavior in the growth cones of living neurons during axon elongation.
J Cell Biol. 115(2):345-63Biological effects of the v-erbA oncogene in transformation of avian erythroid cells.
Molecular Mechanisms in Cellular Growth and Differentiation (eds. Bellve, AR., Vogel, JH.). :137-47Expression of human CSF-1 receptor induces CSF-1-dependent proliferation in murine myeloid but not in T-lymphoid cells.
Leukemia. 5(1):3-7Transgenic mouse models for bone and vascular diseases and gene transfer into hematopoietic cells.
Human Gene Transfer (eds. Cohen-Haguenauer, O., Boiron, M.). 219:227-34Transferrin-polycation-DNA complexes: the effect of polycations on the structure of the complex and DNA delivery to cells.
Proc Natl Acad Sci U S A. 88(10):4255-9DNA-binding transferrin conjugates as functional gene-delivery agents: synthesis by linkage of polylysine or ethidium homodimer to the transferrin carbohydrate moiety.
Bioconjug Chem. 2(4):226-31A simple procedure for the preparation of protected 2'-O-methyl or 2'-O-ethyl ribonucleoside-3'-O-phosphoramidites.
Nucleic Acids Res. 19(21):5965-71Analysis of oncogene function in ES cells and chimaeric mice.
Origins of Human Cancer (CSH Lab Press). :1030-6A novel target cell for c-fos-induced oncogenesis: development of chondrogenic tumours in embryonic stem cell chimeras.
EMBO J. 10(9):2437-50V-myc-transformed macrophages expressing the normal human EGF receptor are induced to proliferate by EGF via a non-autocrine mechanism.
Molecular Biology of Haematopiesis (eds. Sachs, I., Abraham, NG., Weidemann, C., Konwalinka, G.. :453-67Sympathetic hyperplasia and neuroblastomas in transgenic mice expressing polyoma middle T antigen.
New Biol. 2(6):533-43High levels of de novo methylation and altered chromatin structure at CpG islands in cell lines.
Cell. 62(3):503-14A novel B-cell lineage-specific transcription factor present at early but not late stages of differentiation.
Genes Dev. 4(5):849-59Partial Not 1 digests, generated by low enzyme concentration or the presence of ethidium bromide, can be used to extend the range of pulsed-field gel mapping.
Technique. 2:79-87Internal dynamics of flexible molecules.
Cyclohexane, Monatshefte f. Chemie . 1212:2339/349Transferrin-polycation-mediated introduction of DNA into human leukemic cells: stimulation by agents that affect the survival of transfected DNA or modulate transferrin receptor levels.
Proc Natl Acad Sci U S A. 87(11):4033-7Requirement for the C-terminal domain of the v-erbA oncogene protein for biological function and transcriptional repression.
Oncogene. 5(3):309-16Ectopic expression of the erythrocyte band 3 anion exchange protein, using a new avian retrovirus vector.
J Virol. 64(12):5891-902Phosphorylation of the v-erbA protein is required for its function as an oncogene.
Genes Dev. 4(10):1663-76Characterization of fos-induced osteogenic tumours and tumour-derived murine cell lines.
Differentiation. 44(2):122-31Lesion-induced increase in nerve growth factor mRNA is mediated by c-fos.
Proc Natl Acad Sci U S A. 87(10):3899-903Cell cycle-dependent regulation of histone precursor mRNA processing by modulation of U7 snRNA accessibility.
Nature. 346(6285):665-8A regular pattern of two types of 100-residue motif in the sequence of titin.
Nature. 345(6272):273-6A nuclear protein that binds preferentially to methylated DNA in vitro may play a role in the inaccessibility of methylated CpGs in mammalian nuclei.
Philos Trans R Soc Lond B Biol Sci. 326(1235):199-205Increased proteolytic activity is responsible for the aberrant morphogenetic behavior of endothelial cells expressing the middle T oncogene.
Cell. 62(3):435-45The identification of a second cell cycle control on the HO promoter in yeast: cell cycle regulation of SW15 nuclear entry.
Cell. 62(4):631-47The v-erb A oncogene causes repression of erythrocyte-specific genes and an immature, aberrant differentiation phenotype in normal erythroid progenitors.
Oncogene. 5(10):1445-53The expected equilibrium of the CpG dinucleotide in vertebrate genomes under a mutation model.
Proc Natl Acad Sci U S A. 87(12):4692-6A conserved sequence in histone H2A which is a ubiquitination site in higher eucaryotes is not required for growth in Saccharomyces cerevisiae.
Mol Cell Biol. 10(9):4905-113 processing of histone RNA precursors.
Mol Biol Rep. 14(2-3):211-2Transferrin-polycation conjugates as carriers for DNA uptake into cells.
Proc Natl Acad Sci U S A. 87(9):3410-4EMBO medal review. On transferring genes into stem cells and mice.
EMBO J. 9(10):3024-32Oncogenes and transgenic mice.
Growth factors, differentiaion factors and cytokines (ed. Habenicht, A.). :662-83Mouse genetics meets molecular biology at Cold Spring Harbor. Mouse Molecular Genetics sponsored by the Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA, August 29-September 2, 1990.
New Biol. 2(12):1071-4Activity and tissue-specific expression of the transcription factor NF-E1 multigene family.
Genes Dev. 4(10):1650-62v-erbA oncogene activation entails the loss of hormone-dependent regulator activity of c-erbA.
Cell. 61(6):1035-49Receptor-mediated endocytosis of transferrin-polycation conjugates: an efficient way to introduce DNA into hematopoietic cells.
Proc Natl Acad Sci U S A. 87(10):3655-9The testis-specific octamer-binding protein of the sea urchin has a molecular weight of 85 kDa.
Nucleic Acids Res. 17(17):7114Developmental and tissue-specific regulation of a novel transcription factor of the sea urchin.
Genes Dev. 3(5):663-75Co-operation between viral oncogenes in avian erythroid and myeloid leukaemia.
Eur J Clin Invest. 19(6):491-502Two classes of observed frequency for rare-cutter sites in CpG islands.
Nucleic Acids Res. 17(22):9485Dangerous liaisons: spermatozoa as natural vectors for foreign DNA?
Cell. 57(5):701-2Ribozyme mediated destruction of RNA in vivo.
EMBO J. 8(12):3861-6Ribozyme, antisense RNA, and antisense DNA inhibition of U7 small nuclear ribonucleoprotein-mediated histone pre-mRNA processing in vitro.
Mol Cell Biol. 9(10):4479-87Cloning of cDNAs coding for human HMG I and HMG Y proteins: both are capable of binding to the octamer sequence motif.
Nucleic Acids Res. 17(15):5947-59The mutated, myeloid cell-specific growth factor receptor v-fms transforms avian erythroid but not myeloid cells.
Genes Dev. 3(12B):2072-82Mating-type control in Saccharomyces cerevisiae: isolation and characterization of mutants defective in repression by a1-alpha 2.
Mol Cell Biol. 9(10):4523-30In situ analysis of c-fos expression in transgenic mice.
Current Communications in Molecular Biology: Molecular Genetics of Early Drosophila and Mouse Development (ed. Capecchi, MR.). :117-29Expression of v-src induces a myeloproliferative disease in bone-marrow-reconstituted mice.
Genes Dev. 3(6):827-37Identification of a mammalian protein that binds specifically to DNA containing methylated CpGs.
Cell. 58(3):499-507c-fos expression induces bone tumors in transgenic mice.
Oncogene. 4(7):861-5The specific consequences of c-fos expression in transgenic mice.
Prog Nucleic Acid Res Mol Biol. 36:235-45In vivo and in vitro expression of U7 snRNA genes: cis- and trans-acting elements required for RNA polymerase II-directed transcription.
EMBO J. 8(2):539-49The protein CDP, but not CP1, footprints on the CCAAT region of the gamma-globin gene in unfractionated B-cell extracts.
Biochim Biophys Acta. 1007(2):237-42Expression of v-src arrests murine glial cell differentiation.
Oncogene. 4(4):457-64Conserved terminal hairpin sequences of histone mRNA precursors are not involved in duplex formation with the U7 RNA but act as a target site for a distinct processing factor.
Proc Natl Acad Sci U S A. 86(12):4345-9c-fos and polyoma middle T oncogene expression in transgenic mice and embroyonal stem cell chimaeras.
NATO ASI Series. H26, Cell to cell signals in mammalian development (ed. de Laat, SW.):301-10Tumour induction in fetal brain transplants exposed to the viral oncogenes polyoma middle T and v-src.
IARC Sci Publ. (96):267-74Endothelioma cells expressing the polyoma middle T oncogene induce hemangiomas by host cell recruitment.
Cell. 57(6):1053-63Promoter of a somatic histone H2B gene of the sea urchin.
Nucleic Acids Res. 16(9):4175Specific contacts between mammalian U7 snRNA and histone precursor RNA are indispensable for the in vitro 3' RNA processing reaction.
EMBO J. 7(3):801-8A point mutation in the DNA binding domain of the v-myb oncogene of E26 virus confers temperature sensitivity for transformation of myelomonocytic cells.
Oncogene Res. 3(4):313-22Functional analysis of the sea urchin U7 small nuclear RNA.
Mol Cell Biol. 8(3):1076-84Cooperativity of viral oncogenes in avian leukaemia.
IARC Sci Publ. (92):165-70Abnormal glycosylation of the env-sea oncogene product inhibits its proteolytic cleavage and blocks its transforming ability.
Oncogene. 2(4):317-26The -117 mutation in Greek HPFH affects the binding of three nuclear factors to the CCAAT region of the gamma-globin gene.
EMBO J. 7(10):3099-107